3.4.22.55	C303A	catalytically inactive	665588	
3.4.22.55	C303A	inactive	664882	
3.4.22.55	C320A	catalytic residue, inactive mutant enzyme	713154	
3.4.22.55	C320A	catalytically inactive	732048	
3.4.22.55	C320A	forms a dimer only when cell are treated with DRB	664753	
3.4.22.55	D152A	pro-caspase mutant, like the wild-type, this mutant is efficiently processed between the large and the small subunit, however, it is not further processed to seperate the prodomain from the large subunit	664882	
3.4.22.55	D316A	fusion of the linker to the large subunit, toxic when expressed in yeast	664882	
3.4.22.55	D316A/D330A	abolishes auto-processing and reduces enzymatic activity dramatically, 840fold decrease in activity	664882	
3.4.22.55	D316G	uncleavable	665588	
3.4.22.55	D330A	fusion of the linker to the small subunit, slightly greater deleterious effect on enzyme activity than fusion to the large subunit (D316A), toxic when expressed in yeast	664882