2.3.1.167 D166A decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA 755829 2.3.1.167 D34E decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA 755829 2.3.1.167 D372E decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA 755829 2.3.1.167 D390H catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is 96% of the wild-type value 757640 2.3.1.167 D390R catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is improved by 2.3fold 757640 2.3.1.167 F160A mutation negatively affects activity 757765 2.3.1.167 F301A activity against 10-deacetyltaxol is 1.6times more active than wild-type activity, activitys against 10-deacetylbaccatin III is degraded 757765 2.3.1.167 F301V mutant enzyme is 2.85times more active against 10-deacetyltaxol than the wild-type enzyme 757765 2.3.1.167 F400A mutation negatively affects activity 757765 2.3.1.167 F44A activity against 10-deacetyltaxol is nearly undetectable 757765