3.5.1.106 D125A mutation leads to a complete loss of the deformylase activity 3.5.1.106 E221A 70% of wild-type deformylase acticity 3.5.1.106 H245A mutation leads to a complete loss of the deformylase activity 3.5.1.106 S101A mutation leads to a complete loss of the deformylase activity