3.4.22.53 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19251930&form=6&db=m Influence of glutamine infusion on ubiquitin, caspase-3, cathepsins L and B, and m-calpain expression in sheep with nutritionally induced metabolic acidosis. ongoing research,unassigned 1,0 3.4.22.53 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11516996&form=6&db=m The calpain family and human disease. causal interaction,diagnostic usage,unassigned 4,1,0 3.4.22.53 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23889979&form=6&db=m Hypoxia-Triggered m-Calpain Activation Evokes Endoplasmic Reticulum Stress and Neuropathogenesis in a Transgenic Mouse Model of Alzheimer's Disease. ongoing research,unassigned 2,0 3.4.22.53 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30177812&form=6&db=m Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects. causal interaction,ongoing research,unassigned 3,2,0 3.4.22.53 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32937436&form=6&db=m Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment. unassigned - 3.4.22.53 Anthrax http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24085852&form=6&db=m Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis. therapeutic application,unassigned 1,0 3.4.22.53 Aortic Aneurysm http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19720936&form=6&db=m Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms. causal interaction,unassigned 1,0 3.4.22.53 Aortic Aneurysm, Abdominal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33761765&form=6&db=m Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice. causal interaction,ongoing research,therapeutic application,unassigned 2,3,1,0 3.4.22.53 Arsenic Poisoning http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24641850&form=6&db=m [Effects of arsenic poisoning on neuronal cell apoptosis and mRNA and protein expression of calpain 1, calpain 2, and cdk5/p25]. diagnostic usage,ongoing research,unassigned 1,3,0 3.4.22.53 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15501405&form=6&db=m Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs. ongoing research,unassigned 4,0