3.4.18.1	Acquired Immunodeficiency Syndrome	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28078176&form=6&db=m	The function of cathepsins B, D, and X in atherosclerosis.	therapeutic application,unassigned	1,0	
3.4.18.1	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15162377&form=6&db=m	Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.	causal interaction,diagnostic usage,therapeutic application,unassigned	4,4,1,0	
3.4.18.1	Alagille Syndrome	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30087368&form=6&db=m	Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis.	causal interaction,diagnostic usage,unassigned	1,3,0	
3.4.18.1	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23621429&form=6&db=m	Neuroprotective role of ?-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X.	unassigned	-	
3.4.18.1	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30459560&form=6&db=m	Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1?E9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease.	causal interaction,ongoing research,unassigned	1,4,0	
3.4.18.1	Bone Diseases, Metabolic	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31278293&form=6&db=m	Cathepsin Z as a novel potential biomarker for osteoporosis.	causal interaction,diagnostic usage,ongoing research,therapeutic application	3,4,3,4	
3.4.18.1	Breast Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20133781&form=6&db=m	Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.	ongoing research,therapeutic application,unassigned	1,1,0	
3.4.18.1	Carcinogenesis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15162377&form=6&db=m	Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia.	causal interaction,diagnostic usage,therapeutic application,unassigned	4,4,1,0	
3.4.18.1	Carcinogenesis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16025436&form=6&db=m	Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.	causal interaction,diagnostic usage,ongoing research,unassigned	3,1,4,0	
3.4.18.1	Carcinogenesis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23152410&form=6&db=m	IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells.	causal interaction,therapeutic application,unassigned	4,1,0