6.3.4.2 Arthritis, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30334466&form=6&db=m Acellular Fish Skin Grafts and Pig Urinary Bladder Matrix Assessed in the Collagen-Induced Arthritis Mouse Model. ongoing research,therapeutic application,unassigned 2,1,0 6.3.4.2 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21464199&form=6&db=m Cyclopentenyl cytosine induces senescence in breast cancer cells through the nucleolar stress response and activation of p53. ongoing research,unassigned 3,0 6.3.4.2 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1699659&form=6&db=m Enhancement of the toxicity and DNA incorporation of arabinosyl-5-azacytosine and 1-beta-D-arabinofuranosylcytosine by cyclopentenyl cytosine. ongoing research,therapeutic application,unassigned 3,1,0 6.3.4.2 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32209435&form=6&db=m IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors. causal interaction,diagnostic usage,unassigned 1,4,0 6.3.4.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1779227&form=6&db=m The effect of some platinum compounds on the activity of the CTP synthetase of Ehrlich ascites tumor cells: in vitro and in vivo studies. ongoing research,therapeutic application,unassigned 2,2,0 6.3.4.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3593352&form=6&db=m Synthesis of N4-substituted CTP by mammalian CTP synthetase. ongoing research,unassigned 2,0 6.3.4.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3995044&form=6&db=m CTP synthetase from Ehrlich ascites tumor cells. Subunit stoichiometry and regulation of activity. diagnostic usage,unassigned 2,0 6.3.4.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7150287&form=6&db=m Role of GTP in CTP synthetase from Ehrlich ascites tumor cells. unassigned - 6.3.4.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7306558&form=6&db=m Purification and properties of CTP synthetase from Ehrlich ascites tumor cells. diagnostic usage,unassigned 2,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1381200&form=6&db=m Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy. causal interaction,ongoing research,unassigned 4,1,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2347042&form=6&db=m Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride. unassigned - 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3835819&form=6&db=m Potentiation of antimetabolite action by dibromodulcitol in cell culture. causal interaction,unassigned 1,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6180609&form=6&db=m Multi-enzyme-targeted chemotherapy by acivicin and actinomycin. causal interaction,therapeutic application,unassigned 1,2,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6722778&form=6&db=m Origin of increased deoxycytidine excretion into urine of rats bearing Yoshida ascites sarcoma. ongoing research,unassigned 3,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6789025&form=6&db=m Increased concentration of CTP synthetase in hepatoma 3924A: immunological evidence. unassigned - 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7078346&form=6&db=m Rapid in vivo inactivation by acivicin of CTP synthetase, carbamoyl-phosphate synthetase II, and amidophosphoribosyltransferase in hepatoma. unassigned - 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7150366&form=6&db=m Biochemical pharmacology of acivicin in rat hepatoma cells. causal interaction,ongoing research,therapeutic application,unassigned 1,3,3,0 6.3.4.2 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29097181&form=6&db=m CTP synthase forms the cytoophidium in human hepatocellular carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 6.3.4.2 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32209435&form=6&db=m IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors. causal interaction,diagnostic usage,unassigned 1,4,0 6.3.4.2 Carcinosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6722778&form=6&db=m Origin of increased deoxycytidine excretion into urine of rats bearing Yoshida ascites sarcoma. ongoing research,unassigned 3,0 6.3.4.2 Cerebral Hemorrhage http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32776236&form=6&db=m Computed tomography perfusion in patients of stroke with left ventricular assist device. ongoing research,unassigned 2,0 6.3.4.2 Child Nutrition Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31133594&form=6&db=m Cash transfer programmes in lower-income and middle-income countries: understanding pathways to nutritional change-a realist review protocol. causal interaction,therapeutic application,unassigned 3,1,0 6.3.4.2 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21378502&form=6&db=m Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer. therapeutic application,unassigned 1,0 6.3.4.2 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28847964&form=6&db=m Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC. causal interaction,therapeutic application,unassigned 4,2,0 6.3.4.2 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33564769&form=6&db=m Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection. causal interaction,therapeutic application,unassigned 1,1,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24870241&form=6&db=m CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. causal interaction,unassigned 4,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27543071&form=6&db=m Variable phenotype and discrete alterations of immune phenotypes in CTP synthase 1 deficiency: Report of 2 siblings. diagnostic usage,unassigned 3,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27638562&form=6&db=m CTP Synthase 1 Deficiency in Successfully Transplanted Siblings with Combined Immune Deficiency and Chronic Active EBV Infection. causal interaction,unassigned 4,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32161190&form=6&db=m Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33462728&form=6&db=m Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity. causal interaction,unassigned 4,0 6.3.4.2 ctp synthase (glutamine hydrolysing) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34281398&form=6&db=m Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival. causal interaction,unassigned 4,0 6.3.4.2 Epstein-Barr Virus Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27638562&form=6&db=m CTP Synthase 1 Deficiency in Successfully Transplanted Siblings with Combined Immune Deficiency and Chronic Active EBV Infection. causal interaction,unassigned 4,0 6.3.4.2 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19260077&form=6&db=m Another ten stories in antiviral drug discovery (part C): "Old" and "new" antivirals, strategies, and perspectives. causal interaction,therapeutic application,unassigned 1,4,0 6.3.4.2 Herpes Simplex http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19260077&form=6&db=m Another ten stories in antiviral drug discovery (part C): "Old" and "new" antivirals, strategies, and perspectives. causal interaction,therapeutic application,unassigned 1,4,0 6.3.4.2 HIV Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19260077&form=6&db=m Another ten stories in antiviral drug discovery (part C): "Old" and "new" antivirals, strategies, and perspectives. causal interaction,therapeutic application,unassigned 1,4,0 6.3.4.2 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9333163&form=6&db=m DNA vaccination with the major outer-membrane protein gene induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection. therapeutic application,unassigned 1,0 6.3.4.2 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9333163&form=6&db=m DNA vaccination with the major outer-membrane protein gene induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection. therapeutic application,unassigned 1,0 6.3.4.2 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15169771&form=6&db=m Escherichia coli nucleoside diphosphate kinase interactions with T4 phage proteins of deoxyribonucleotide synthesis and possible regulatory functions. unassigned - 6.3.4.2 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19260077&form=6&db=m Another ten stories in antiviral drug discovery (part C): "Old" and "new" antivirals, strategies, and perspectives. causal interaction,therapeutic application,unassigned 1,4,0 6.3.4.2 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29282224&form=6&db=m Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility. unassigned - 6.3.4.2 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7575666&form=6&db=m The IMP dehydrogenase inhibitor mycophenolic acid antagonizes the CTP synthetase inhibitor 3-deazauridine in MOLT-3 human leukemia cells: a central role for phosphoribosyl pyrophosphate. diagnostic usage,ongoing research,unassigned 3,4,0 6.3.4.2 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8309250&form=6&db=m Resistance to cytosine arabinoside in acute leukemia: the significance of mutations in CTP synthetase. causal interaction,diagnostic usage,unassigned 3,1,0 6.3.4.2 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8365402&form=6&db=m Evidence for transformation-related increase in CTP synthetase activity in situ in human lymphoblastic leukemia. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,1,4 6.3.4.2 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32161190&form=6&db=m Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 6.3.4.2 Leukemia, Myeloid, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10738128&form=6&db=m Cyclopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia: a promising target for chemotherapy. causal interaction,ongoing research,therapeutic application,unassigned 1,3,4,0 6.3.4.2 Leukemia, T-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32161190&form=6&db=m Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 6.3.4.2 Liver Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28205032&form=6&db=m Safety of laparoscopic radical gastrectomy in gastric cancer patients with liver cirrhosis. diagnostic usage,unassigned 3,0 6.3.4.2 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34299130&form=6&db=m Protective Effect of Polysaccharides Extracted from Cudrania tricuspidata Fruit against Cisplatin-Induced Cytotoxicity in Macrophages and a Mouse Model. ongoing research,therapeutic application,unassigned 3,3,0 6.3.4.2 Lupus Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24677949&form=6&db=m A22: consensus treatment plans for induction therapy in childhood proliferative lupus nephritis-status of use in daily clinical care. diagnostic usage,therapeutic application,unassigned 1,4,0 6.3.4.2 Lymphadenopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26564415&form=6&db=m Features of Computed Tomography Perfusion of Mediastinal Lymphadenopathies: a Pathology-based Retrospective Study. therapeutic application,unassigned 2,0 6.3.4.2 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32161190&form=6&db=m Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 6.3.4.2 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34281398&form=6&db=m Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival. causal interaction,unassigned 4,0 6.3.4.2 Lymphoproliferative Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6572096&form=6&db=m Cytidine triphosphate synthetase activity in lymphoproliferative disorders. therapeutic application,unassigned 1,0 6.3.4.2 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27402641&form=6&db=m Factors Associated With the Risk of Acute Malnutrition Among Children Aged 6 to 36 Months in Households Targeted by an Emergency Cash Transfer Program. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 6.3.4.2 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28441944&form=6&db=m Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,2,0 6.3.4.2 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26614709&form=6&db=m Circulating Tumor Cells, DNA, and mRNA: Potential for Clinical Utility in Patients With Melanoma. unassigned - 6.3.4.2 Nasopharyngeal Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17633263&form=6&db=m [Cytidine triphosphate synthetase gene expressed in the homogenous nasopharyngeal carcinoma tissue cells] ongoing research,unassigned 3,0 6.3.4.2 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31173206&form=6&db=m Identification of critical genes associated with human osteosarcoma metastasis based on integrated gene expression profiling. causal interaction,unassigned 3,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=203856&form=6&db=m Increased CTP synthetase activity in cancer cells. diagnostic usage,ongoing research,unassigned 2,3,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=420952&form=6&db=m Ara-C metabolism: implications for drug resistance and drug interactions. ongoing research,therapeutic application,unassigned 3,1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=476649&form=6&db=m Penetration of 3-deazauridine into human brain, intracerebral tumor, and cerebrospinal fluid. therapeutic application,unassigned 1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1381200&form=6&db=m Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy. causal interaction,ongoing research,unassigned 4,1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1779227&form=6&db=m The effect of some platinum compounds on the activity of the CTP synthetase of Ehrlich ascites tumor cells: in vitro and in vivo studies. ongoing research,therapeutic application,unassigned 2,2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2113467&form=6&db=m Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomes. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2347042&form=6&db=m Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride. unassigned - 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3593352&form=6&db=m Synthesis of N4-substituted CTP by mammalian CTP synthetase. ongoing research,unassigned 2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3995044&form=6&db=m CTP synthetase from Ehrlich ascites tumor cells. Subunit stoichiometry and regulation of activity. diagnostic usage,unassigned 2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6288502&form=6&db=m Activities of various enzymes of pyrimidine nucleotide and DNA syntheses in normal and neoplastic human tissues. unassigned - 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7150287&form=6&db=m Role of GTP in CTP synthetase from Ehrlich ascites tumor cells. unassigned - 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7306558&form=6&db=m Purification and properties of CTP synthetase from Ehrlich ascites tumor cells. diagnostic usage,unassigned 2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7471043&form=6&db=m Increased cytidine 5'-triphosphate synthetase activity in rat and human tumors. causal interaction,ongoing research,unassigned 1,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10413291&form=6&db=m Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. causal interaction,therapeutic application,unassigned 3,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10738128&form=6&db=m Cyclopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia: a promising target for chemotherapy. causal interaction,ongoing research,therapeutic application,unassigned 1,3,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11243234&form=6&db=m Comments on: cylopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia: a promising target for chemotherapy. A.C. Verschuur et al. Eur J Cancer 2000, 36, 627-635. therapeutic application,unassigned 3,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16820675&form=6&db=m Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy. causal interaction,therapeutic application,unassigned 3,1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17691910&form=6&db=m Cyclopentenyl cytosine (CPEC): an overview of its in vitro and in vivo activity. causal interaction,therapeutic application,unassigned 3,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21378502&form=6&db=m Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer. therapeutic application,unassigned 1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24477477&form=6&db=m Glutamine deprivation initiates reversible assembly of mammalian rods and rings. therapeutic application,unassigned 1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27537329&form=6&db=m Discretization of Gene Expression Data Unmasks Molecular Subgroups Recurring in Different Human Cancer Types. causal interaction,unassigned 3,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28811571&form=6&db=m Identification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells. causal interaction,ongoing research,therapeutic application,unassigned 2,3,2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29097181&form=6&db=m CTP synthase forms the cytoophidium in human hepatocellular carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29112802&form=6&db=m Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Anti-Inflammatory Drugs and/or with Active Spinal Lesions. therapeutic application,unassigned 2,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30184506&form=6&db=m Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30877335&form=6&db=m Cancer targeting peptides. causal interaction,therapeutic application,unassigned 3,4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30988367&form=6&db=m Ectopic miR-975 induces CTP synthase directed cell proliferation and differentiation in Drosophila melanogaster. causal interaction,unassigned 4,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32184263&form=6&db=m SNAP29 mediates the assembly of histidine-induced CTP synthase filaments in proximity to the cytokeratin network. ongoing research,unassigned 1,0 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32978066&form=6&db=m MEASURE: Multisite studies for validation and improvement of a highly efficient culture (HEC) assay for detection of undifferentiated human pluripotent stem cells intermingled in cell therapy products. unassigned - 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34022203&form=6&db=m CTPS and IMPDH form cytoophidia in developmental thymocytes. unassigned - 6.3.4.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34262348&form=6&db=m No Detection of Pseudocapsule of Tumor-Parenchyma Interface on Multidetector Computed Tomography (MDCT) Images: Clinical Significance and Histological Reflections in Renal Cell Carcinoma. diagnostic usage,therapeutic application,unassigned 3,1,0 6.3.4.2 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12220665&form=6&db=m Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells. therapeutic application,unassigned 1,0 6.3.4.2 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16133534&form=6&db=m Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma. ongoing research,unassigned 4,0 6.3.4.2 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31173206&form=6&db=m Identification of critical genes associated with human osteosarcoma metastasis based on integrated gene expression profiling. causal interaction,unassigned 3,0 6.3.4.2 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28697344&form=6&db=m MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. ongoing research,therapeutic application,unassigned 1,1,0 6.3.4.2 Periodontal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30298515&form=6&db=m Label-free quantitative proteomic analysis of human periodontal ligament stem cells by high-resolution mass spectrometry. diagnostic usage,unassigned 4,0 6.3.4.2 Poxviridae Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12615300&form=6&db=m Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives. therapeutic application,unassigned 3,0 6.3.4.2 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33576499&form=6&db=m Energy deficiency caused by CTPS downregulation in decidua may contribute to pre-eclampsia by impairing decidualization. causal interaction,unassigned 4,0 6.3.4.2 Precursor Cell Lymphoblastic Leukemia-Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8365402&form=6&db=m Evidence for transformation-related increase in CTP synthetase activity in situ in human lymphoblastic leukemia. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,1,4 6.3.4.2 Precursor Cell Lymphoblastic Leukemia-Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9210431&form=6&db=m Determination of CTP synthetase activity in crude cell homogenates by a fast and sensitive non-radiochemical assay using anion-exchange high-performance liquid chromatography. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 6.3.4.2 Precursor Cell Lymphoblastic Leukemia-Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9598149&form=6&db=m Increased activity of cytidine Triphosphate synthetase in pediatric acute lymphoblastic leukemia. causal interaction,diagnostic usage,unassigned 1,2,0 6.3.4.2 Primary Immunodeficiency Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29176466&form=6&db=m The Challenge of Next Generation Sequencing in a Boy With Severe Mononucleosis and EBV-related Lymphoma. causal interaction,unassigned 1,0 6.3.4.2 Rothmund-Thomson Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33462728&form=6&db=m Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity. causal interaction,unassigned 4,0 6.3.4.2 Scleroderma, Localized http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31967352&form=6&db=m A retrospective study: Impact of consensus treatment plans on systemic therapy of pediatric morphea. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,4,0 6.3.4.2 Severe Acute Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28441944&form=6&db=m Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,2,0 6.3.4.2 Severe Combined Immunodeficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33462728&form=6&db=m Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity. causal interaction,unassigned 4,0 6.3.4.2 Smallpox http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12615300&form=6&db=m Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives. therapeutic application,unassigned 3,0 6.3.4.2 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27116391&form=6&db=m Ubiquitination and filamentous structure of cytidine triphosphate synthase. causal interaction,unassigned 1,0 6.3.4.2 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30184506&form=6&db=m Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 6.3.4.2 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28205032&form=6&db=m Safety of laparoscopic radical gastrectomy in gastric cancer patients with liver cirrhosis. diagnostic usage,unassigned 3,0 6.3.4.2 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33719272&form=6&db=m [Effects of Toosendanin on the formation of CTPS cytoophidium in human gastric cancer cell MKN-45 and its mechanism]. ongoing research,unassigned 2,0 6.3.4.2 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11353848&form=6&db=m Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness. therapeutic application,unassigned 4,0 6.3.4.2 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17331943&form=6&db=m Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness. therapeutic application,unassigned 4,0 6.3.4.2 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21840216&form=6&db=m Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness. therapeutic application,unassigned 2,0 6.3.4.2 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22865834&form=6&db=m Synthesis and Biological Evaluation of CTP Synthetase Inhibitors as Potential Agents for the Treatment of African Trypanosomiasis. causal interaction,therapeutic application,unassigned 2,4,0 6.3.4.2 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26097035&form=6&db=m Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. unassigned - 6.3.4.2 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28475832&form=6&db=m A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors. ongoing research,therapeutic application,unassigned 2,1,0 6.3.4.2 Vascular System Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24325297&form=6&db=m Smooth muscle-specific drug targets for next-generation drug-eluting stent. causal interaction,therapeutic application,unassigned 4,1,0 6.3.4.2 Wiskott-Aldrich Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33462728&form=6&db=m Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity. causal interaction,unassigned 4,0