3.6.1.12 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20534734&form=6&db=m Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. diagnostic usage,ongoing research,unassigned 3,2,0 3.6.1.12 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26075750&form=6&db=m Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 3.6.1.12 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32716908&form=6&db=m Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 3.6.1.12 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34113564&form=6&db=m DCTPP1, an Oncogene Regulated by miR-378a-3p, Promotes Proliferation of Breast Cancer via DNA Repair Signaling Pathway. ongoing research,therapeutic application,unassigned 1,1,0 3.6.1.12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24085278&form=6&db=m dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,4,0 3.6.1.12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26771665&form=6&db=m Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1. ongoing research,therapeutic application,unassigned 1,4,0 3.6.1.12 Chondrocalcinosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2935159&form=6&db=m Partial characterization of synovial fluid nucleotide pyrophosphohydrolase. unassigned - 3.6.1.12 Chondrocalcinosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3009553&form=6&db=m Pyrophosphohydrolase activity and inorganic pyrophosphate content of cultured human skin fibroblasts. Elevated levels in some patients with calcium pyrophosphate dihydrate deposition disease. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,4,0 3.6.1.12 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20534734&form=6&db=m Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. diagnostic usage,ongoing research,unassigned 3,2,0 3.6.1.12 dctp diphosphatase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=999989&form=6&db=m Erythrocyte ITP pyrophosphohydrolase deficiency in a psychiatric population. causal interaction,unassigned 3,0 3.6.1.12 dctp diphosphatase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2560342&form=6&db=m Further evidence for a 'new' purine defect, inosine triphosphate (ITP) pyrophosphohydrolase deficiency. causal interaction,unassigned 3,0 3.6.1.12 dctp diphosphatase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3036112&form=6&db=m Purine metabolism in normal and high-ITP human erythrocytes. Attempts to evaluate the ability to store the cells. causal interaction,unassigned 2,0 3.6.1.12 dctp diphosphatase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31954130&form=6&db=m The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products. causal interaction,unassigned 4,0 3.6.1.12 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32716908&form=6&db=m Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 3.6.1.12 Esophageal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24085278&form=6&db=m dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,4,0 3.6.1.12 hypoxanthine phosphoribosyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=999989&form=6&db=m Erythrocyte ITP pyrophosphohydrolase deficiency in a psychiatric population. causal interaction,unassigned 3,0 3.6.1.12 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=168406&form=6&db=m Synthesis of functional bacteriophage T4-delayed early mRNA in the absence of protein synthesis. unassigned - 3.6.1.12 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6273500&form=6&db=m Partial exclusion of bacteriophage T2 by bacteriophage T4: induction of early enzymes by excluded T2. diagnostic usage,unassigned 3,0 3.6.1.12 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14410470&form=6&db=m Deoxycytidine triphosphatase, an enzyme induced by bacteriophage infection. ongoing research,unassigned 2,0 3.6.1.12 Joint Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2935159&form=6&db=m Partial characterization of synovial fluid nucleotide pyrophosphohydrolase. unassigned - 3.6.1.12 Joint Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2998408&form=6&db=m Adenosine triphosphate pyrophosphohydrolase and neutral inorganic pyrophosphatase in pathologic joint fluids. Elevated pyrophosphohydrolase in calcium pyrophosphate dihydrate crystal deposition disease. unassigned - 3.6.1.12 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26771665&form=6&db=m Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1. ongoing research,therapeutic application,unassigned 1,4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15740738&form=6&db=m Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions. diagnostic usage,unassigned 3,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24085278&form=6&db=m dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26075750&form=6&db=m Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26771665&form=6&db=m Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1. ongoing research,therapeutic application,unassigned 1,4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27612427&form=6&db=m DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28145708&form=6&db=m Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1. causal interaction,therapeutic application,unassigned 3,1,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28508636&form=6&db=m Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors. diagnostic usage,therapeutic application,unassigned 1,1,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29711738&form=6&db=m New Tripodal, "Supercharged" Analogues of Adenosine Nucleotides: Inhibitors for the Fhit Ap3 A Hydrolase. therapeutic application,unassigned 4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29874556&form=6&db=m Autophagy induced by overexpression of DCTPP1 promotes tumor progression and predicts poor clinical outcome in prostate cancer. causal interaction,diagnostic usage,unassigned 4,4,0 3.6.1.12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34113564&form=6&db=m DCTPP1, an Oncogene Regulated by miR-378a-3p, Promotes Proliferation of Breast Cancer via DNA Repair Signaling Pathway. ongoing research,therapeutic application,unassigned 1,1,0 3.6.1.12 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32593299&form=6&db=m Prognostic significance of MYCN related genes in pediatric neuroblastoma: a study based on TARGET and GEO datasets. therapeutic application,unassigned 1,0 3.6.1.12 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2935159&form=6&db=m Partial characterization of synovial fluid nucleotide pyrophosphohydrolase. unassigned - 3.6.1.12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29874556&form=6&db=m Autophagy induced by overexpression of DCTPP1 promotes tumor progression and predicts poor clinical outcome in prostate cancer. causal interaction,diagnostic usage,unassigned 4,4,0 3.6.1.12 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25379943&form=6&db=m Comparative proteomics analysis of gastric cancer stem cells. causal interaction,diagnostic usage,unassigned 3,3,0 3.6.1.12 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27612427&form=6&db=m DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 3.6.1.12 Vascular Calcification http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15775396&form=6&db=m [Mechanism of vascular calcification] ongoing research,unassigned 1,0 3.6.1.12 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30926608&form=6&db=m Substrate specificity of the pyrophosphohydrolase LpxH determines the asymmetry of Bordetella pertussis lipid A. causal interaction,therapeutic application,unassigned 3,3,0