2.8.1.2 3-mercaptopyruvate sulfurtransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29668565&form=6&db=m The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock. causal interaction,unassigned 3,0 2.8.1.2 3-mercaptopyruvate sulfurtransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30649358&form=6&db=m Effect of 3-mercaptopyruvate Sulfurtransferase Deficiency on the Development of Multiorgan Failure, Inflammation, and Wound Healing in Mice Subjected to Burn Injury. causal interaction,diagnostic usage,unassigned 4,2,0 2.8.1.2 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30500457&form=6&db=m Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 2.8.1.2 Anaphylaxis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32012740&form=6&db=m Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria. unassigned - 2.8.1.2 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20446008&form=6&db=m The expression and activity of cystathionine-gamma-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines. ongoing research,unassigned 4,0 2.8.1.2 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27038311&form=6&db=m Upregulation of 3-MST Relates to Neuronal Autophagy After Traumatic Brain Injury in Mice. causal interaction,ongoing research,unassigned 1,4,0 2.8.1.2 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30500457&form=6&db=m Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 2.8.1.2 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8094343&form=6&db=m Transamination and transsulphuration of L-cysteine in Ehrlich ascites tumor cells and mouse liver. The nonenzymatic reaction of L-cysteine with pyruvate. diagnostic usage,unassigned 1,0 2.8.1.2 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32027885&form=6&db=m Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 2.8.1.2 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33546491&form=6&db=m ?MST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage. causal interaction,unassigned 4,0 2.8.1.2 Cerebral Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32813542&form=6&db=m 3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway. diagnostic usage,ongoing research,unassigned 2,1,0 2.8.1.2 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30500457&form=6&db=m Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 2.8.1.2 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31382676&form=6&db=m N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells. therapeutic application,unassigned 1,0 2.8.1.2 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32183148&form=6&db=m Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.8.1.2 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33856792&form=6&db=m Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer. causal interaction,ongoing research,therapeutic application,unassigned 1,3,4,0 2.8.1.2 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32340322&form=6&db=m Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.8.1.2 Dyspnea http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27942208&form=6&db=m Three-minute constant rate step test for detecting exertional dyspnea relief after bronchodilation in COPD. diagnostic usage,ongoing research,unassigned 3,3,0 2.8.1.2 Endotoxemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27748832&form=6&db=m Effect of endotoxemia in mice genetically deficient in cystathionine-?-lyase, cystathionine-?-synthase or 3-mercaptopyruvate sulfurtransferase. causal interaction,ongoing research,unassigned 4,3,0 2.8.1.2 Glaucoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27890826&form=6&db=m Relevant variations and neuroprotecive effect of hydrogen sulfide in a rat glaucoma model. unassigned - 2.8.1.2 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25532835&form=6&db=m Is development of high-grade gliomas sulfur-dependent? causal interaction,diagnostic usage,ongoing research,unassigned 1,3,3,0 2.8.1.2 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26743493&form=6&db=m Maternal N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and prevents programmed hypertension in male offspring exposed to prenatal dexamethasone and postnatal high-fat diet. ongoing research,therapeutic application,unassigned 4,1,0 2.8.1.2 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27251093&form=6&db=m N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. diagnostic usage,unassigned 3,0 2.8.1.2 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32027885&form=6&db=m Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 2.8.1.2 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33546491&form=6&db=m ?MST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage. causal interaction,unassigned 4,0 2.8.1.2 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30825200&form=6&db=m Altered gene expression of hydrogen sulfide-producing enzymes in the liver and muscles tissues of hyperthyroid rats. diagnostic usage,ongoing research,unassigned 1,4,0 2.8.1.2 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20446008&form=6&db=m The expression and activity of cystathionine-gamma-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines. ongoing research,unassigned 4,0 2.8.1.2 Mucopolysaccharidosis III http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32335228&form=6&db=m Murine cellular model of mucopolysaccharidosis, type IIIB (MPS IIIB) - A preliminary study with particular emphasis on the non-oxidative l-cysteine metabolism. diagnostic usage,ongoing research,unassigned 2,2,0 2.8.1.2 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32027885&form=6&db=m Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8094343&form=6&db=m Transamination and transsulphuration of L-cysteine in Ehrlich ascites tumor cells and mouse liver. The nonenzymatic reaction of L-cysteine with pyruvate. diagnostic usage,unassigned 1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25532835&form=6&db=m Is development of high-grade gliomas sulfur-dependent? causal interaction,diagnostic usage,ongoing research,unassigned 1,3,3,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28558483&form=6&db=m Hydrogen Sulfide and Polysulfide Signaling. causal interaction,unassigned 1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29790379&form=6&db=m A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? causal interaction,unassigned 1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29793450&form=6&db=m Endogenous H2S producing enzymes are involved in apoptosis induction in clear cell renal cell carcinoma. unassigned - 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30283315&form=6&db=m Hydrogen Sulfide and Hydrogen Sulfide-Synthesizing Enzymes Are Altered in a Case of Oral Adenoid Cystic Carcinoma. ongoing research,unassigned 2,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30483098&form=6&db=m Hydrogen Sulfide-Synthesizing Enzymes Are Altered in a Case of Oral Cavity Mucoepidermoid Carcinoma. ongoing research,unassigned 1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30500457&form=6&db=m Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32183148&form=6&db=m Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32882966&form=6&db=m Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer. causal interaction,unassigned 1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33088447&form=6&db=m Aerobic Training-induced Upregulation of YAP1 and Prevention of Cardiac Pathological Hypertrophy in Male Rats. diagnostic usage,ongoing research,unassigned 1,1,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33456997&form=6&db=m Crocin reverses 1-methyl-3-nitroso-1-nitroguanidine (MNNG)-induced malignant transformation in GES-1 cells through the Nrf2/Hippo signaling pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,1 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33856792&form=6&db=m Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer. causal interaction,ongoing research,therapeutic application,unassigned 1,3,4,0 2.8.1.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34133955&form=6&db=m Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner. therapeutic application,unassigned 1,0 2.8.1.2 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20446008&form=6&db=m The expression and activity of cystathionine-gamma-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines. ongoing research,unassigned 4,0 2.8.1.2 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30194156&form=6&db=m Inhibition of Human Neuroblastoma Cell Proliferation by N-acetyl-L-cysteine as a Result of Increased Sulfane Sulfur Level. diagnostic usage,ongoing research,unassigned 3,4,0 2.8.1.2 Non-alcoholic Fatty Liver Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28877979&form=6&db=m Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway. ongoing research,therapeutic application,unassigned 2,1,0 2.8.1.2 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29927219&form=6&db=m [Adipocytic Endogenous Hydrogen Sulfide-Function,Regulation and Diseases]. unassigned - 2.8.1.2 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32183900&form=6&db=m The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway against experimental osteoarthritis. therapeutic application,unassigned 1,0 2.8.1.2 Osteoporosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33714972&form=6&db=m Association of Hydrogen Sulfide with Femoral Bone Mineral Density in Osteoporosis Patients: A Preliminary Study. causal interaction,diagnostic usage,unassigned 3,1,0 2.8.1.2 Polycythemia Vera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9584858&form=6&db=m The activity of 3-mercaptopyruvate sulfurtransferase in erythrocytes from patients with polycythemia vera. diagnostic usage,ongoing research,unassigned 1,2,0 2.8.1.2 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27942208&form=6&db=m Three-minute constant rate step test for detecting exertional dyspnea relief after bronchodilation in COPD. diagnostic usage,ongoing research,unassigned 3,3,0 2.8.1.2 Reperfusion Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32027885&form=6&db=m Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 2.8.1.2 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28804545&form=6&db=m Hydrogen sulfide prevents diaphragm weakness in cecal ligation puncture-induced sepsis by preservation of mitochondrial function. unassigned - 2.8.1.2 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23805308&form=6&db=m Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,1,0 2.8.1.2 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32494243&form=6&db=m Sequential butylphthalide therapy combined with dual antiplatelet therapy in the treatment of acute cerebral infarction. therapeutic application,unassigned 2,0