2.7.11.27 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28094871&form=6&db=m Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes. therapeutic application,unassigned 1,0 2.7.11.27 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18776129&form=6&db=m Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 2.7.11.27 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11554766&form=6&db=m Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line. ongoing research,unassigned 3,0 2.7.11.27 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19284883&form=6&db=m Activation of an AMP-activated protein kinase is involved in post-diapause development of Artemia franciscana encysted embryos. diagnostic usage,unassigned 3,0 2.7.11.27 Fatty Liver, Alcoholic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20041784&form=6&db=m Protective effect of Codonopsis lanceolata root extract against alcoholic fatty liver in the rat. causal interaction,unassigned 3,0 2.7.11.27 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33885249&form=6&db=m Glucose deprivation affects the expression of genes encoding cAMP-activated protein kinase and related proteins in U87 glioma cells in ERN1 dependent manner. causal interaction,ongoing research,unassigned 1,2,0 2.7.11.27 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18842111&form=6&db=m Increased hepatic lipogenesis in insulin resistance and type 2 diabetes is associated to AMPK signaling pathway upregulation in Psammomys obesus. unassigned - 2.7.11.27 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17098823&form=6&db=m Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy. causal interaction,unassigned 1,0 2.7.11.27 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17934342&form=6&db=m Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha. causal interaction,unassigned 1,0 2.7.11.27 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20221584&form=6&db=m Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo. unassigned - 2.7.11.27 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23108783&form=6&db=m Birt-Hogg-Dubé syndrome: from gene discovery to molecularly targeted therapies. therapeutic application,unassigned 2,0 2.7.11.27 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28094871&form=6&db=m Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes. therapeutic application,unassigned 1,0 2.7.11.27 Mitochondrial Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17332500&form=6&db=m Diverse cytopathologies in mitochondrial disease are caused by AMP-activated protein kinase signaling. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,2,0 2.7.11.27 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28213331&form=6&db=m Mitochondrial metabolism and energy sensing in tumor progression. ongoing research,unassigned 3,0 2.7.11.27 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18255222&form=6&db=m AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. causal interaction,therapeutic application,unassigned 1,2,0 2.7.11.27 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20613671&form=6&db=m The role of hypothalamic AMP-activated protein kinase in ovariectomy-induced obesity in rats. causal interaction,unassigned 2,0 2.7.11.27 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19874425&form=6&db=m Metformin attenuates ovarian cancer cell growth in an AMP- kinase dispensable manner. causal interaction,diagnostic usage,therapeutic application,unassigned 1,1,3,0 2.7.11.27 Overnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18784329&form=6&db=m Maternal overnutrition suppresses the phosphorylation of 5'-AMP-activated protein kinase in liver, but not skeletal muscle, in the fetal and neonatal sheep. causal interaction,ongoing research,therapeutic application,unassigned 4,4,1,0