1.1.99.2 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26208971&form=6&db=m A novel compound heterozygous mutation in a Chinese boy with L-2-hydroxyglutaric aciduria: a case study. causal interaction,unassigned 3,0 1.1.99.2 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18671189&form=6&db=m L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene: neuroimaging findings. causal interaction,unassigned 1,0 1.1.99.2 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20727073&form=6&db=m Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations. diagnostic usage,unassigned 1,0 1.1.99.2 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30108105&form=6&db=m Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,2,0 1.1.99.2 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31131312&form=6&db=m Epigenetic dysregulation by aberrant metabolism in renal cell carcinoma can be reversed with Ascorbic acid. unassigned - 1.1.99.2 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30108105&form=6&db=m Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,2,0 1.1.99.2 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31131312&form=6&db=m Epigenetic dysregulation by aberrant metabolism in renal cell carcinoma can be reversed with Ascorbic acid. unassigned - 1.1.99.2 Drug Resistant Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25982940&form=6&db=m White matter abnormalities in an adult patient with l-2-hydroxyglutaric aciduria. causal interaction,unassigned 1,0 1.1.99.2 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21625441&form=6&db=m Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. causal interaction,unassigned 3,0 1.1.99.2 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31233712&form=6&db=m LCN2-interacting proteins and their expression patterns in brain tumors. causal interaction,diagnostic usage,unassigned 1,3,0 1.1.99.2 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25982940&form=6&db=m White matter abnormalities in an adult patient with l-2-hydroxyglutaric aciduria. causal interaction,unassigned 1,0 1.1.99.2 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32928875&form=6&db=m Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney. causal interaction,therapeutic application,unassigned 3,1,0 1.1.99.2 l-2-hydroxyglutarate dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=116084&form=6&db=m Familial hyperlysinaemia due to L-lysine alpha-ketoglutarate reductase deficiency: results of attempted treatment. causal interaction,therapeutic application,unassigned 4,2,0 1.1.99.2 l-2-hydroxyglutarate dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22459673&form=6&db=m Adult manifestation of L-2-hydroxyglutarate dehydrogenase deficiency by a novel mutation. causal interaction,unassigned 4,0 1.1.99.2 l-2-hydroxyglutarate dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28137912&form=6&db=m L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. causal interaction,ongoing research,unassigned 3,2,0 1.1.99.2 Leukoencephalopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23296366&form=6&db=m Metabolite proofreading, a neglected aspect of intermediary metabolism. unassigned - 1.1.99.2 Leukoencephalopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28137912&form=6&db=m L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. causal interaction,ongoing research,unassigned 3,2,0 1.1.99.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21625441&form=6&db=m Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. causal interaction,unassigned 3,0 1.1.99.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25182153&form=6&db=m L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer. causal interaction,ongoing research,unassigned 3,4,0 1.1.99.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26097881&form=6&db=m Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer. causal interaction,unassigned 2,0 1.1.99.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30108105&form=6&db=m Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,2,0 1.1.99.2 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32928875&form=6&db=m Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney. causal interaction,therapeutic application,unassigned 3,1,0 1.1.99.2 Neuroinflammatory Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28137912&form=6&db=m L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. causal interaction,ongoing research,unassigned 3,2,0 1.1.99.2 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34131130&form=6&db=m An L-2-hydroxyglutarate biosensor based on specific transcriptional regulator LhgR. ongoing research,therapeutic application,unassigned 1,1,0