6.3.4.2	additional information	-	additional information	xanthine and related compounds inhibit CTPS activity with IC50 = 0.16-0.58 mM. The presence of an 8-oxo function enhances the inhibition to IC50 = 0.060-0.121 mM. Raising the pH from 8.0 to 8.5 results in slightly increased inhibition of NH3-dependent CTP formation by the xanthines	702613	
6.3.4.2	0.04	-	CTP	wild-type, pH 8.1, 37°C	715549	
6.3.4.2	0.042	-	CTP	wild-type, pH 8.1, 37°C	715549	
6.3.4.2	0.045	-	CTP	mutant S571A, pH 8.1, 37°C	715549	
6.3.4.2	0.05	-	CTP	IC50: 0.05 mM	649000	
6.3.4.2	0.057	-	CTP	C-terminal deletion mutant, pH 8.1, 37°C	715549	
6.3.4.2	0.06	-	uric acid	pH 8.0, Gln-dependent CTP formation	702613	
6.3.4.2	0.063	-	3,7-dimethyluric acid	pH 8.0, Gln-dependent CTP formation	702613	
6.3.4.2	0.067	-	1,3,7-trimethyluric acid	pH 8.0, Gln-dependent CTP formation	702613	
6.3.4.2	0.07	-	1,3,7-trimethyluric acid	pH 8.0, NH3-dependent CTP formation	702613