2.3.1.54 acetyl-CoA - 727989, 735819, 736361, 736638 2.3.1.54 S-adenosyl-L-methionine - 745316 2.3.1.54 [4Fe-4S]-center the [4Fe-4S] cluster of enzyme PFL-AE is coordinated by the cysteines of a conserved CX3CX2C motif, with the fourth unique iron coordinated by S-adenosyl-L-methionine. PFL-AE contains six cysteine residues (Cys12, Cys29, Cys33, Cys36, Cys94, Cys102) and only Cys29, Cys33, and Cys36 are involved in coordinating the iron sulfur cluster 745316