2.3.1.37 N-methyl-pyridoxal 5'-phosphate in vitro, mutant D279A 486856 2.3.1.37 pyridoxal 5'-phosphate - 486808, 486810, 486812, 486813, 486814, 486815, 486816, 486817, 486818, 486820, 486821, 486822, 486823, 486824, 486827, 486828, 486829, 486830, 486831, 486833, 486834, 486836, 486837, 486838, 486840, 486841, 486842, 486843, 486845, 486846, 486847, 486848, 486850, 486851, 486852, 486859, 661787, 718696, 719402, 719419, 719861, 720074, 756091, 756100, 756270, 756455, 756863, 756992, 757255, 757560, 757676, 757677, 757686, 758234, 758299, 758425 2.3.1.37 pyridoxal 5'-phosphate 1 or 2 molecules of cofactor are bound per subunit of MW 50000 in hemiapoenzyme or holoenzyme, required 486826 2.3.1.37 pyridoxal 5'-phosphate absolute requirement 486811 2.3.1.37 pyridoxal 5'-phosphate activates 486809 2.3.1.37 pyridoxal 5'-phosphate bound to the enzyme through a Schiff base linkage 486820, 486825 2.3.1.37 pyridoxal 5'-phosphate contains 1 molar equivalent of pyridoxal 5'-phosphate 486844 2.3.1.37 pyridoxal 5'-phosphate content in ALAS-E wild-type and Lys313 mutants 486849 2.3.1.37 pyridoxal 5'-phosphate dependent on 677263, 735711, 736116, 736454, 736491, 755944 2.3.1.37 pyridoxal 5'-phosphate dependent on, succinyl-CoA binding effects the cofactor-binding site of wild-type and mutant enzymes and induces distinct changes to the chiral environment of the cofactor, overview 735684