1.14.15.24 heme - 714018 1.14.15.24 Ferredoxin the hydroxylase is strictly dependent upon reduced ferredoxin which cannot be replaced by NADPH 714293 1.14.15.24 additional information the beta-carotene hydroxylase reaction proceeds in the absence of externally added cofactors. However, electron donors, such as NAD, NADPH, and ascorbate were able to stimulate the reaction 714995 1.14.15.24 additional information non-heme hydroxylase 715012 1.14.15.24 FAD - 715432 1.14.15.24 additional information NADPH (1 mM) yields 2.5fold elevation in activity 715432 1.14.15.24 additional information the monooxygenase cofactors consist of FAD, NADPH, and ATP. This cofactor combination increases the activity of CrtZ about 1.5fold compared to the control 715432 1.14.15.24 NADPH NADPH (1 mM) yields 2.5fold elevation in activity 715432 1.14.15.24 Ferredoxin reduced ferredoxin is required for activity 716977 1.14.15.24 additional information NADPH is not required for activity 716977 1.14.15.24 cytochrome P450 the enzyme is a cytochrome P450 monooxygenase 748597