2.1.1.214 ? x * 51109, His-tagged enzyme, sequence calculation -, 757844 2.1.1.214 additional information composed of at least two subunits that are associated in vivo: Trm11, which is the catalytic subunit, and Trm112, that contains a zinc-finger 705993 2.1.1.214 additional information composed of at least two subunits that are associated in vivo: Trm11p (Yol124c), which is the catalytic subunit, and Trm112p (Ynr046w), a putative zinc-binding protein. While deletion of TRM11 has no detectable phenotype under laboratory conditions, deletion of TRM112 leads to a severe growth defect, suggesting that it has additional functions in the cell. Trm112p is associated with at least four proteins: two tRNA methyltransferases (Trm9p and Trm11p), one putative protein methyltransferase (Mtc6p/Ydr140w), and one protein with a Rossmann fold dehydrogenase domain (Lys9p/Ynr050c) 675961 2.1.1.214 additional information Trm112p is a small 15-kDa protein that contains a zinc finger domain, a motif composed of four cysteines arranged with a certain spacing, which can form a secondary structure resembling a finger 712436