6.2.1.1 ADP + acetate + CoA 37% of the activity relative to ATP Penicillium chrysogenum AMP + diphosphate + acetyl-CoA - ? 14 6.2.1.1 ADP + acetate + CoA 20% of the activity relative to ATP Bradyrhizobium japonicum AMP + diphosphate + acetyl-CoA - ? 14 6.2.1.1 ADP + phosphate + acetyl-CoA - Pyrococcus furiosus ATP + acetate + CoA - ? 160 6.2.1.1 ATP + 2-methylvalerate + CoA - Methanothermobacter thermautotrophicus AMP + diphosphate + 2-methylvaleryl-CoA - ? 453707 6.2.1.1 ATP + 3-bromopropanoate + CoA - Saccharomyces cerevisiae AMP + diphosphate + 3-bromopropanoyl-CoA - ? 141 6.2.1.1 ATP + 3-chloropropanoate + CoA - Saccharomyces cerevisiae AMP + diphosphate + 3-chloropropanoyl-CoA - ? 140 6.2.1.1 ATP + 3-methylvalerate + CoA mutant enzyme W416G catalyzes the reaction, no activity with wild-type enzyme Methanothermobacter thermautotrophicus AMP + diphosphate + 3-methylvaleryl-CoA - ? 387935 6.2.1.1 ATP + 4-methylvalerate + CoA mutant enzyme W416G catalyzes the reaction, no activity with wild-type enzyme Methanothermobacter thermautotrophicus AMP + diphosphate + 4-methylvaleryl-CoA - ? 387938 6.2.1.1 ATP + acetate + CoA - Haloarcula marismortui AMP + diphosphate + acetyl-CoA - r 12 6.2.1.1 ATP + acetate + CoA - Aliivibrio fischeri AMP + diphosphate + acetyl-CoA - ? 12