2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA - Streptococcus pneumoniae S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Bacillus megaterium shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Priestia megaterium S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Enterococcus faecalis shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Enterococcus faecalis S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Lactobacillus plantarum shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Lactiplantibacillus plantarum S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Lactococcus lactis shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Lactococcus lactis S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Nocardia corynebacteroides shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Rhodococcus corynebacterioides S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-negative 23 S rRNAs are methylated at G745. 23S rRNA of Gram-positives is methylated at G748. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate. Streptococcus thermophilus shows intrinsic 23S rRNA methylation at G748. No methylation is determined with the recombinant protein in vivo or in vitro Streptococcus thermophilus S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-positive 23S rRNAs are methylated at G748. 23S rRNA of Gram-negatives is methylated at G745. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate Bacillus subtilis S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-positive 23S rRNAs are methylated at G748. 23S rRNA of Gram-negatives is methylated at G745. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate Streptococcus pneumoniae S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351 2.1.1.188 S-adenosyl-L-methionine + guanine748 in 23S rRNA Gram-positive 23S rRNAs are methylated at G748. 23S rRNA of Gram-negatives is methylated at G745. The position of an RNA methylation defines a sharp division between the Gram-negative and Gram-positive bacteria. Specificity of methylation is determined solely by the methyltransferase enzyme and is independent of the origin of the rRNA substrate Corynebacterium glutamicum S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA - ? 407351