2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	-	Berberis stolonifera	S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine	-	?	6866	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	-	Berberis stolonifera	?	-	?	369509	
2.1.1.117	S-Adenosyl-L-methionine + (R,S)-2,3,9,10-tetrahydroxytetrahydroprotoberberine	methylated at 50% of the rate of (S)-scoulerine	Berberis wilsoniae	?	-	?	6870	
2.1.1.117	S-Adenosyl-L-methionine + (S)-3,9-dihydroxy-2,10-dimethoxytetrahydroprotoberberine	methylated at 4% of the rate of (S)-scoulerine	Berberis wilsoniae	?	-	?	6871	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	-	Berberis wilsoniae	S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine	-	?	6866	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	central role in orotoberberine biosynthesis	Berberis wilsoniae	?	-	?	369509	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	-	Coptis chinensis	S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine	-	ir	6866	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	-	Coptis japonica	S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine	-	?	6866	
2.1.1.117	S-Adenosyl-L-methionine + (S)-scoulerine	the enzyme is responsible for a late step in the biosynthesis of berberine	Coptis japonica	?	-	?	369509	
2.1.1.117	S-Adenosyl-L-methionine + 6-O-methylnorlaudanosoline	8% of the activity relative to (S)-scoulerine	Coptis japonica	?	-	?	6868