2.1.1.117 additional information enzyme catalyzes O-methylation at C-9 and C-2, and O-methylation events occur first at C-9 and then at C-2 Stephania intermedia ? - - 89 2.1.1.117 additional information enzyme is a scoulerine-9-O-methyltransferase for the biosynthesis of chelerythrine in California poppy, it produces 7-O-methylated, 3'-O-methylated and dual O-methylated products from reticuline and norreticuline, and 9-O-methylated tetrahydrocolumbamine, 2-O-methylscoulerine and tetrahydropalmatine from scoulerine Eschscholzia californica subsp. californica ? - - 89 2.1.1.117 S-adenosyl-L-homocysteine + (S)-tetrahydropalmatrubine - Stephania intermedia S-adenosyl-L-homocysteine + (S)-tetrahydropalmatine - ? 456353 2.1.1.117 S-Adenosyl-L-methionine + (R,S)-2,3,9,10-tetrahydroxytetrahydroprotoberberine methylated at 50% of the rate of (S)-scoulerine Berberis wilsoniae ? - ? 6870 2.1.1.117 S-Adenosyl-L-methionine + (S)-3,9-dihydroxy-2,10-dimethoxytetrahydroprotoberberine methylated at 4% of the rate of (S)-scoulerine Berberis wilsoniae ? - ? 6871 2.1.1.117 S-adenosyl-L-methionine + (S)-norreticuline - Eschscholzia californica subsp. californica S-adenosyl-L-homocysteine + norcodamine + norlaudanine - ? 456364 2.1.1.117 S-adenosyl-L-methionine + (S)-reticuline - Eschscholzia californica subsp. californica S-adenosyl-L-homocysteine + codamine + laudanine - ? 456366 2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine - Papaver somniferum S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine - ? 6866 2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine - Berberis stolonifera S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine - ? 6866 2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine - Berberis wilsoniae S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine - ? 6866