3.4.24.49	casein + H2O	endopeptidase	Bothrops jararaca	hydrolyzed casein	-	?	15305	
3.4.24.49	casein + H2O	-	Echis carinatus	?	-	?	15445	
3.4.24.49	casein + H2O	enzyme stabilized by CaCl2	Bothrops jararaca	?	-	?	15445	
3.4.24.49	collagen I + H2O	-	Bothrops jararaca	?	-	?	36832	
3.4.24.49	Collagen IV + H2O	-	Bothrops jararaca	?	-	?	17094	
3.4.24.49	collagen VI + H2O	from human placenta	Bothrops jararaca	?	-	?	398840	
3.4.24.49	Fibrin + H2O	-	Bothrops jararaca	?	-	?	16541	
3.4.24.49	Fibrin + H2O	the enzyme specifically cleaves the alpha-polymer and alpha-chain of the fibrin molecule, in contrast gamma-gamma dimer and beta-chain of the fibrin are found to be resistant to the enzyme	Echis carinatus	?	-	?	16541	
3.4.24.49	fibrinogen	-	Bothrops jararaca	?	-	?	384717	
3.4.24.49	Fibrinogen + H2O	-	Bothrops jararaca	?	-	?	15619	
3.4.24.49	Fibrinogen + H2O	-	Echis carinatus	?	-	?	15619	
3.4.24.49	Fibrinogen + H2O	identification of peptides generated by bothropasin proteolytic activity. Among the fibrinogen derived peptides identified by mass spectrometry, analogous of endogenous products like the fibrinopeptides A and B are found, as well as other sequences described in the literature with vasoactive or antiangiogenic properties	Bothrops jararaca	?	-	?	15619	
3.4.24.49	fibrinonectin + H2O	from human plasma	Bothrops jararaca	?	-	?	418624	
3.4.24.49	fibronectin	-	Bothrops jararaca	?	-	?	384718	
3.4.24.49	Fibronectin + H2O	-	Bothrops jararaca	?	-	?	15394	
3.4.24.49	Fibronectin + H2O	-	Echis carinatus	?	-	?	15394	
3.4.24.49	Fibronectin + H2O	identification of peptides generated by bothropasin proteolytic activity. For most of the peptides no biological activity is described. Exceptionally a peptide that is known as a bond site for B cells is found	Bothrops jararaca	?	-	?	15394	
3.4.24.49	gelatin	-	Bothrops jararaca	?	-	?	384767	
3.4.24.49	Gelatin + H2O	-	Echis carinatus	?	-	?	16570	
3.4.24.49	Insulin B-chain + H2O	cleavage of His5-Leu, His10-Leu, Ala14-Leu, Tyr16-Leu and Phe24-Phe	Bothrops jararaca	Hydrolyzed insulin B-chain	-	?	15577	
3.4.24.49	Matrigel + H2O	-	Bothrops jararaca	?	-	?	418821	
3.4.24.49	additional information	comparison of hemorrhagic, caseinolytic and fibrinogenolytic activities of metalloproteinases HF3, bothropasin, the DC protein and metalloproteinase BJ-PI. Hemorrhagic activity of bothropasin is 0.006 mg to produce a hemorrhagic area of 1 cm2. Fibrinogenolytic activity of bothropasin is 9.8 units/mg	Bothrops jararaca	?	-	?	89	
3.4.24.49	additional information	bothropasin degradation profiles of fibrinogen, fibronectin, vitronectin, von Willebrand factor, collagens IV and VI, laminin and Matrigel in comparison to the other three snake venom metalloproteinases of Bothrops jararaca, binding to plasma and extracellular matrix proteins, overview. Collagen I is degraded only by bothropasin	Bothrops jararaca	?	-	?	89	
3.4.24.49	type I collagen	-	Bothrops jararaca	?	-	?	385862	
3.4.24.49	Vitronectin + H2O	from human plasma	Bothrops jararaca	?	-	?	16775	
3.4.24.49	von Willebrand factor + H2O	-	Bothrops jararaca	?	-	?	367553