3.4.16.6	alpha-factor-Lys-Arg + H2O	maturation takes place in sequential manner	Saccharomyces cerevisiae	mature active alpha-factor + Lys + Arg	-	?	361722	
3.4.16.6	angiotensin 1 + H2O	truncated KexA releases amino acid residues from the C terminus of angiotensin I	Aspergillus oryzae	?	-	?	431603	
3.4.16.6	benzoyl-Gly-Arg + H2O	enzyme shows very low activity	Aspergillus oryzae	benzoyl-Gly + L-arginine	-	?	431650	
3.4.16.6	benzoyl-Phe-Ala-Arg + H2O	-	Saccharomyces cerevisiae	benzoyl-Phe-Ala + Arg	-	?	64977	
3.4.16.6	benzyloxycarbonyl-Gly-Lys + H2O	enzyme shows very low activity	Aspergillus oryzae	benzyloxycarbonyl-Gly + L-lysine	-	?	431665	
3.4.16.6	benzyloxycarbonyl-Phe-Leu + H2O	enzyme shows very low activity	Aspergillus oryzae	benzyloxycarbonyl-Phe + L-leucine	-	?	431673	
3.4.16.6	benzyloxycarbonyl-Phe-Tyr-Leu + H2O	-	Aspergillus oryzae	benzyloxycarbonyl-Phe-Tyr + L-leucine	-	?	431674	
3.4.16.6	benzyloxycarbonyl-Tyr-Leu + H2O	enzyme shows very low activity	Aspergillus oryzae	benzyloxycarbonyl-Tyr + L-leucine	-	?	431675	
3.4.16.6	bradykinin I + H2O	truncated KexA releases amino acid residues from the C terminus of bradykinin I	Aspergillus oryzae	?	-	?	431716	
3.4.16.6	dansyl-L-Ala-L-Arg + H2O	-	Homo sapiens	dansyl-L-Ala + L-Arg	-	?	384568	
3.4.16.6	dansyl-L-Ala-L-Arg + H2O	-	Rattus norvegicus	dansyl-L-Ala + L-Arg	-	?	384568	
3.4.16.6	Dansyl-Phe-Ala-Arg + H2O	-	Drosophila melanogaster	Dansyl-Phe-Ala + Arg	-	?	15078	
3.4.16.6	furylacryloyl-Ala-Arg + H2O	-	Saccharomyces cerevisiae	furylacryloyl-Ala + Arg	-	?	36765	
3.4.16.6	furylacryloyl-Ala-Arg + H2O	activity assay	Saccharomyces cerevisiae	furylacryloyl-Ala + Arg	-	?	36765	
3.4.16.6	furylacryloyl-Ala-Lys + H2O	-	Saccharomyces cerevisiae	furylacryloyl-Ala + Lys	-	?	361698	
3.4.16.6	additional information	specificity	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	specificity	Triticum aestivum	?	-	?	89	
3.4.16.6	additional information	activity of individual domains of the enzyme. Domain 1B is more active at neutral pH and greatly prefers C-terminal Arg over Lys, whereas domain 2 is more active at pH 5-6 and slightly prefers C-terminal Lys over Arg	Drosophila melanogaster	?	-	?	89	
3.4.16.6	additional information	the enzyme has a narrow specificity for lysyl ar arginyl residues at the C-terminus of the substrate	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	role in the processing of both the alpha-pheromone and the killer toxin precursors	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	involved in the C-terminal processing of the lysine and arginine residues from the precursors of K1 and K2 killer toxins and alpha-factor (mating pheromone)	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	the enzyme functions in processing of proteins that transit the secretory pathway	Drosophila melanogaster	?	-	?	89	
3.4.16.6	additional information	plays a role in polypeptide processing in yeast	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	specific for the removal of basic amino acids from prohormone processing intermediates, in mammalian cells	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	preferential release of a C-terminal arginine or lysine residue	Saccharomyces cerevisiae	?	-	?	89	
3.4.16.6	additional information	preferential release of a C-terminal arginine or lysine residue	Kluyveromyces lactis	?	-	?	89	
3.4.16.6	[Leu5]enkephalin-Arg6 + H2O	-	Saccharomyces cerevisiae	?	-	?	361725	
3.4.16.6	[Leu5]enkephalin-Lys6 + H2O	-	Saccharomyces cerevisiae	?	-	?	361726	
3.4.16.6	[Met5]enkephalin-Arg6 + H2O	-	Saccharomyces cerevisiae	?	-	?	361723	
3.4.16.6	[Met5]enkephalin-Lys6 + H2O	-	Saccharomyces cerevisiae	?	-	?	361724