3.1.6.13	4-methylumbelliferyl-alpha-idopyranosiduronic acid 2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-alpha-iduronate + sulfate	-	?	446747	
3.1.6.13	4-methylumbelliferyl-alpha-iduronate 2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-alpha-iduronate + sulfate	-	?	429766	
3.1.6.13	4-methylumbelliferyl-alpha-iduronide 2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-alpha-iduronide + sulfate	-	?	399671	
3.1.6.13	4-methylumbelliferyl-alpha-iduronide-2-sulfate + H2O	-	Mus musculus	4-methylumbelliferyl-alpha-iduronide + sulfate	-	?	399672	
3.1.6.13	4-methylumbelliferyl-alpha-iduronide-2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-alpha-iduronide + sulfate	-	?	399672	
3.1.6.13	4-methylumbelliferyl-alpha-iduronide-2-sulfate + H2O	-	Danio rerio	4-methylumbelliferyl-alpha-iduronide + sulfate	-	?	399672	
3.1.6.13	4-methylumbelliferyl-alpha-L-iduronate 2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferol + L-iduronate 2-sulfate	-	?	416334	
3.1.6.13	4-methylumbelliferyl-alpha-L-iduronate 2-sulfate + H2O	artificial substrate	Homo sapiens	4-methylumbelliferol + L-iduronate 2-sulfate	-	?	416334	
3.1.6.13	4-methylumbelliferyl-alpha-L-iduronide-2-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-alpha-L-iduronide + sulfate	-	?	411323	
3.1.6.13	dermatan sulfate + H2O	-	Mus musculus	dermatan + sulfate	-	?	93804	
3.1.6.13	dermatan sulfate + H2O	-	Homo sapiens	dermatan + sulfate	-	?	93804	
3.1.6.13	dermatan sulfate + H2O	-	Rattus norvegicus	dermatan + sulfate	-	?	93804	
3.1.6.13	heparan sulfate + H2O	-	Mus musculus	dermatan + sulfate	-	?	93824	
3.1.6.13	heparan sulfate + H2O	-	Homo sapiens	dermatan + sulfate	-	?	93824	
3.1.6.13	heparan sulfate + H2O	-	Rattus norvegicus	dermatan + sulfate	-	?	93824	
3.1.6.13	heparin + H2O	-	Homo sapiens	desulfated heparin + sulfate	-	?	93825	
3.1.6.13	heparin + H2O	-	Rattus norvegicus	desulfated heparin + sulfate	-	?	93825	
3.1.6.13	additional information	The enzyme has a potential role in normal pathway of lysosomal degradation of secretory peptides and is likely to be essential to maintain pancreatic beta-cell function	Mus musculus	?	-	?	89	
3.1.6.13	additional information	the enzyme is involved in the catabolism of the mucopolysaccharides heparan and dermatan sulfate	Homo sapiens	?	-	?	89	
3.1.6.13	additional information	the enzyme is involved in the catabolism of the mucopolysaccharides heparan and dermatan sulfate	Rattus norvegicus	?	-	?	89	
3.1.6.13	additional information	the enzyme is involved in the sequential degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate	Homo sapiens	?	-	?	89	
3.1.6.13	additional information	the enzyme is responsible for heparin sulfate and dermatan sulfate degradation	Homo sapiens	?	-	?	89	
3.1.6.13	additional information	involved in the degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. An enzyme deficiency causes the lysosomal storage disorder muco-polysaccharidosis type II	Homo sapiens	?	-	?	89	
3.1.6.13	additional information	mucopolysaccharidosis type II is a lysosomal storage disorder related to a deficiency in the enzyme iduronate-2-sulfatase	Homo sapiens	?	-	?	89	
3.1.6.13	additional information	mechanism follows a SN2 nucleophilic attack of the formylglycine FGH84 on the sulfur atom to generate the covalent formylglycine-S adduct, followed by elimination of bound sulfate and rehydration of the resultant formylglycine aldehyde. Residues H229, H138, D334 and K347 are likely to play active roles in proton transfer or activation of water during the reaction cycle	Homo sapiens	?	-	?	89	
3.1.6.13	O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol + H2O	-	Homo sapiens	O-(alpha-L-idopyranosyluronic acid)-(1-4)-2,5-anhydro-D-mannitol + sulfate	-	?	93827	
3.1.6.13	O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + H2O	-	Homo sapiens	O-(alpha-L-idopyranosyluronic acid)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + sulfate	-	?	93826	
3.1.6.13	O-(alpha-L-idopyranosyluronic acid-2-sulfate)-(1-4)-2,5 anhydromannose-6-sulfate	-	Homo sapiens	?	-	?	364686	
3.1.6.13	O-(alpha-L-iduronic acid 2-sulfate)-(1-3)-2,5-anhydro-D-talitol 4-sulfate + H2O	-	Homo sapiens	O-(alpha-L-iduronic acid)-(1-3)-2,5-anhydro-D-talitol 4-sulfate + sulfate	-	?	93828	
3.1.6.13	O-(alpha-L-iduronic acid 2-sulfate)-(1-4)-D-O-(alpha 2-sulfaminoglucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid 2-sulfate)-D-O-2,5-anhydro-mannitol 6-sulfate + H2O	-	Homo sapiens	O-(alpha-L-iduronic acid)-(1-4)-D-O-(alpha 2-sulfaminoglucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid)-D-O-2,5-anhydro-mannitol 6-sulfate + sulfate	-	?	93830	
3.1.6.13	O-(alpha-L-iduronic acid 2-sulfate)-(1-4)-D-O-(alpha 2-sulfaminoglucosamine 6-sulfate)-(1-4)-O-(beta-D-glucuronic acid or L-iduronic acid)-(1-4)-D-O-(alpha-N-acetylglucosamine)-(1-3)-D-O-gulonic acid + H2O	-	Homo sapiens	O-(alpha-L-iduronic acid)-(1-4)-D-O-(alpha 2-sulfaminoglucosamine 6-sulfate)-(1-4)-O-(beta-D-glucuronic acid or L-iduronic acid)-(1-4)-D-O-(alpha-N-acetylglucosamine)-(1-3)-D-O-gulonic acid + sulfate	-	?	93832	
3.1.6.13	O-(alpha-L-iduronic acid 2-sulfate)-(1-4)-D-O-(alpha glucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid 2-sulfate)-D-O-2,5-anhydro-mannitol 6-sulfate + H2O	-	Homo sapiens	O-(alpha-L-iduronic acid)-(1-4)-D-O-(alpha glucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid)-D-O-2,5-anhydro-mannitol 6-sulfate + sulfate	-	?	93831	
3.1.6.13	O-(alpha-L-iduronic acid 2-sulfate)-(1-4)-D-O-(alpha-N-acetylglucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid 2-sulfate)-D-O-2,5-anhydro-mannitol 6-sulfate + H2O	-	Homo sapiens	O-(alpha-L-iduronic acid)-(1-4)-D-O (alpha N-acetylglucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid)-D-O-2,5-anhydro-mannitol 6-sulfate + sulfate	-	?	93829