2.1.1.256 additional information active site structure with bound ligands, S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and sinefungin, overview Pyrococcus furiosus ? - ? 89 2.1.1.256 additional information docking model of TrmN in complex with tRNAPhe of Thermus thermophilus Thermus thermophilus ? - ? 89 2.1.1.256 S-adenosyl-L-methionine + guanine37 in tRNATrp - Thermococcus kodakarensis S-adenosyl-L-homocysteine + N2-methylguanine37 in tRNATrp - ? 456502 2.1.1.256 S-adenosyl-L-methionine + guanine54 in tRNATrp - Thermococcus kodakarensis S-adenosyl-L-homocysteine + N2-methylguanine54 in tRNATrp - ? 456527 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA the enzyme specifically modifies tRNAPhe at guanosine 6 in the tRNA acceptor stem Thermus thermophilus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA - ? 419579 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA the enzyme specifically modifies tRNAPhe at guanosine 6 in the tRNA acceptor stem Pyrococcus furiosus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA - ? 419579 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA the enzyme specifically modifies tRNAPhe at guanosine 6 in the tRNA acceptor stem. Contribution of the THUMP domain in tRNA recognition and catalysis, substrate binding and ligand-induced conformational changes in the RFM domain Pyrococcus furiosus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA - ? 419579 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA the enzyme specifically modifies tRNAPhe at guanosine 6 in the tRNA acceptor stem. Contribution of the THUMP domain in tRNA recognition and catalysis, substrate binding and ligand-induced conformational changes in the RFM domain, overview Thermus thermophilus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA - ? 419579 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA(Phe) production of a small amount of N2-dimethylguanine6 in tRNA(Phe) Thermus thermophilus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA(Phe) - ? 443895 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA(Phe) production of a small amount of N2-dimethylguanine6 in tRNA(Phe) Pyrococcus furiosus S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA(Phe) - ? 443895 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA(Phe) production of a small amount of N2-dimethylguanine6 in tRNA(Phe) Thermus thermophilus DSM 7039 S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA(Phe) - ? 443895 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNACys Trm14 generates m2G at position 6 in tRNACys Methanocaldococcus jannaschii S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNACys - ? 419578 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNACys wild-type or G6A/C67U tRNACys transcripts as substrates, Trm14 generates m2G at position 6 in tRNACys, i.e. tRNACys m2G6-forming activity Methanocaldococcus jannaschii S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNACys - ? 419578 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNACys Trm14 generates m2G at position 6 in tRNACys Methanocaldococcus jannaschii JAL-1 S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNACys - ? 419578 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNACys wild-type or G6A/C67U tRNACys transcripts as substrates, Trm14 generates m2G at position 6 in tRNACys, i.e. tRNACys m2G6-forming activity Methanocaldococcus jannaschii JAL-1 S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNACys - ? 419578 2.1.1.256 S-adenosyl-L-methionine + guanine67 in tRNATrp - Thermococcus kodakarensis S-adenosyl-L-homocysteine + N2-methylguanine67 in tRNATrp - ? 454614 2.1.1.256 S-adenosyl-L-methionine + guanine8 in tRNATrp - Thermococcus kodakarensis S-adenosyl-L-homocysteine + N2-methylguanine8 in tRNATrp - ? 456528