2.1.1.137	additional information	monomethylarsonous acid is not methylated	Homo sapiens	?	-	?	89	
2.1.1.137	additional information	As3MT methylates inorganic arsenic and its metabolites	Homo sapiens	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Gallus gallus	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Mus musculus	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Rhodopseudomonas palustris	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Oncorhynchus mykiss	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Strongylocentrotus purpuratus	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Ciona intestinalis	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Pan troglodytes	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Rattus norvegicus	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Homo sapiens	?	-	?	89	
2.1.1.137	additional information	enzyme evolutionary analysis	Bos taurus	?	-	?	89	
2.1.1.137	additional information	genetic susceptibility to arsenic toxicity in Asian is different from Africans and Caucasians, overview	Homo sapiens	?	-	?	89	
2.1.1.137	additional information	the enzyme is responsible for the removal of arsenic as the volatile arsines from the bacteria producing trimethylarsine via successive methylation	Rhodopseudomonas palustris	?	-	?	89	
2.1.1.137	additional information	besides methylarsonate and dimethylarsinate, the enzyme also produces trimethylarsenite and dimethylarsine gases	Tetrahymena pyriformis	?	-	?	89	
2.1.1.137	additional information	the enzyme does not methylate selenium and tellurium	Homo sapiens	?	-	?	89	
2.1.1.137	additional information	upon incubation with arsenite, dimethylarsinate and a small amount of methylarsinate are detected in the reaction system within 0.5 h	Arthrospira platensis	?	-	-	89	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Gallus gallus	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Mus musculus	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Homo sapiens	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Rattus norvegicus	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Bos taurus	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Oryctolagus cuniculus	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Tetrahymena pyriformis	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Rhodopseudomonas palustris	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Macaca mulatta	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Oncorhynchus mykiss	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Ciona intestinalis	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Cricetinae	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Pan troglodytes	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Methanosarcina acetivorans	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Clostridium sp.	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Pseudomonas alcaligenes	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Cyanidioschyzon sp.	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Bacillus sp. CX-1	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	AS3MT may contribute to variation in arsenic metabolism and, perhaps, arsenic-dependent carcinogenesis in humans	Homo sapiens	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	hAS3MT is the key enzyme in the pathway for methylation of iAs in human hepatic cells	Homo sapiens	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic	Rhodopseudomonas palustris	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	ArsM catalyzes the formation of a number of methylated intermediates from arsenite, with trimethylarsine as the end product	Rhodopseudomonas palustris	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	As3MT enzyme is indispensable for conversion of the arsenic metabolites to their corresponding methylated products, metabolism of arsenic proceeds through sequential reduction and oxidative methylation involving several enzymes including the arsenic (+3) methyltransferase, overview	Homo sapiens	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic	Rhodopseudomonas palustris CGA009	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	ArsM catalyzes the formation of a number of methylated intermediates from arsenite, with trimethylarsine as the end product	Rhodopseudomonas palustris CGA009	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Clostridium sp. BXM	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Pseudomonas alcaligenes NBRC 14159	S-adenosyl-L-homocysteine + methylarsonate	-	?	319610	
2.1.1.137	S-adenosyl-L-methionine + arsenite	the first product, methylarsonate, undergoes a second round of methylation faster than it dissociates from the enzyme. The second product, dimethylarsinate, dissociates faster than it undergoes the third round of methylation to the third and final product, trimethylarsine	Cyanidioschyzon sp.	S-adenosyl-L-homocysteine + methylarsonate + dimethylarsinate + trimethylarsine	-	?	421354	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Homo sapiens	S-adenosyl-L-homocysteine + methylarsonate + dimethylarsinous acid + dimethylarsinic acid	-	?	421355	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Homo sapiens	S-adenosyl-L-homocysteine + monomethylarsonate + dimethylarsinic acid	-	?	421356	
2.1.1.137	S-adenosyl-L-methionine + arsenite	maximal conversion of arsenite to monomethylarsonate occurs at about 0.1 mM arsenite. Higher substrate concentrations inhibit monomethylarsonate yields. The production of dimethylarsinic acid increases as arsenite concentration increases from 0.0005 to 0.0083 mM, and then quickly decreases to zero	Homo sapiens	S-adenosyl-L-homocysteine + monomethylarsonate + dimethylarsinic acid	-	?	421356	
2.1.1.137	S-adenosyl-L-methionine + arsenite	the enzyme methylates arsenite to dimethylarsinic acid as an end product and produces monomethylarsonous acid and monomethylarsonic acid as intermediates	Danio rerio	S-adenosyl-L-homocysteine + monomethylarsonous acid + monomethylarsonic acid + dimethylarsinic acid	-	?	421358	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Arthrospira platensis	S-adenosyl-L-homocysteine + methylarsenate	-	?	456415	
2.1.1.137	S-adenosyl-L-methionine + arsenite	-	Cyanidioschyzon sp. 5508	S-adenosyl-L-homocysteine + methylarsenate(III)	-	?	456416	
2.1.1.137	S-adenosyl-L-methionine + methylarsinate	-	Arthrospira platensis	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	456569	
2.1.1.137	S-adenosyl-L-methionine + methylarsonate	-	Homo sapiens	S-adenosyl-L-homocysteine + dimethylarsinous acid + dimethylarsinic acid	-	?	421410	
2.1.1.137	S-adenosyl-L-methionine + methylarsonate	-	Homo sapiens	S-adenosyl-L-homocysteine + dimethylarsinous acid	-	?	456570	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Homo sapiens	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Rattus norvegicus	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Tetrahymena pyriformis	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Rhodopseudomonas palustris	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Methanosarcina acetivorans	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Clostridium sp.	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Cyanidioschyzon sp.	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Bacillus sp. CX-1	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Pseudomonas alcaligenes	S-adenosyl-L-homocysteine + dimethylarsinate	the enzyme also produces also produces dimethylarsine and trimethylarsine gases as by-products	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Clostridium sp. BXM	S-adenosyl-L-homocysteine + dimethylarsinate	-	?	377744	
2.1.1.137	S-adenosyl-L-methionine + methylarsonite	-	Pseudomonas alcaligenes NBRC 14159	S-adenosyl-L-homocysteine + dimethylarsinate	the enzyme also produces also produces dimethylarsine and trimethylarsine gases as by-products	?	377744	
2.1.1.137	S-adenosyl-L-methionine + phenylarsenite	-	Cyanidioschyzon sp. 5508	S-adenosyl-L-homocysteine + phenylmethylarsenate(III)	-	?	456587