2.1.1.128	S-adenosyl-L-homocysteine + (S)-reticuline	-	Coptis japonica	S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine	-	?	394983	
2.1.1.128	S-Adenosyl-L-methionine + (R)-norlaudanosoline	-	Coptis japonica	S-Adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	-	?	6891	
2.1.1.128	S-Adenosyl-L-methionine + (R)-norlaudanosoline	92% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline in the ratio 8:2	?	6891	
2.1.1.128	S-Adenosyl-L-methionine + (R,S)-2,3-dihydroxy-9,10-dimethoxytetrahydroprotoberberine	5% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + ?	-	?	6897	
2.1.1.128	S-Adenosyl-L-methionine + (R,S)-4'-O-methylnorlaudanosoline	34% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + norprotosinomenine	-	?	6892	
2.1.1.128	S-Adenosyl-L-methionine + (R,S)-5'-O-methylnorlaudanosoline	81% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + 6-O-methyllaudanosoline	-	?	6893	
2.1.1.128	S-adenosyl-L-methionine + (R,S)-norlaudanosoline	-	Coptis japonica	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	-	?	451808	
2.1.1.128	S-adenosyl-L-methionine + (R,S)-norlaudanosoline	-	Argemone platyceras	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	-	?	451808	
2.1.1.128	S-adenosyl-L-methionine + (R,S)-norlaudanosoline	-	Thalictrum flavum subsp. glaucum	S-adenosyl-L-homocysteine + (RS)-6-O-methylnorlaudanosoline	-	?	456359	
2.1.1.128	S-adenosyl-L-methionine + (RS)-norcoclaurine	-	Papaver somniferum	S-adenosyl-L-homocysteine + (RS)-coclaurine	-	?	394984	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	-	Eschscholzia californica	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	-	Coptis japonica	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	-	Coptis japonica	S-adenosyl-L-homocysteine + (S)-coclaurine	-	ir	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	-	Coptis chinensis	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	-	Coptis teeta	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	preferred substrate	Papaver somniferum	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	putative rate-limiting step enzymes in benzylisoquinoline alkaloid biosynthesis	Papaver somniferum	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norcoclaurine	putative rate-limiting step enzymes in benzylisoquinoline alkaloid biosynthesis	Coptis japonica	S-adenosyl-L-homocysteine + (S)-coclaurine	-	?	386680	
2.1.1.128	S-adenosyl-L-methionine + (S)-norlaudanosoline	-	Argemone platyceras	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline in the ratio 8:2	?	6890	
2.1.1.128	S-adenosyl-L-methionine + (S)-norlaudanosoline	activity with (R,S)-norlaudanosoline is 76% of the activity with (S)-norcoclaurine	Coptis japonica	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline	-	?	6890	
2.1.1.128	S-adenosyl-L-methionine + (S)-norlaudanosoline	-	Papaver somniferum	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline	-	?	386681	
2.1.1.128	S-adenosyl-L-methionine + (S)-norlaudanosoline	-	Coptis japonica	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline	-	?	386681	
2.1.1.128	S-adenosyl-L-methionine + (S)-norlaudanosoline	putative rate-limiting step enzymes in benzylisoquinoline alkaloid biosynthesis	Eschscholzia californica	S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline	-	?	386681	
2.1.1.128	S-Adenosyl-L-methionine + (S)-scoulerine	1% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + jatrorrhizine	-	?	6895	
2.1.1.128	S-Adenosyl-L-methionine + 2,3-dihydroxy-9,10-dimethoxyprotoberberine	7% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + tetrahydrojatrorrhizine	-	?	6896	
2.1.1.128	S-Adenosyl-L-methionine + laudanosoline	79% of the activity with (S)-norlaudanosoline	Argemone platyceras	S-Adenosyl-L-homocysteine + tetrahydrocolumbamine	-	?	6894	
2.1.1.128	S-adenosyl-L-methionine + laudanosoline	low activity	Eschscholzia californica	?	-	?	389724	
2.1.1.128	S-adenosyl-L-methionine + laudanosoline	low activity	Coptis japonica	?	-	?	389724	
2.1.1.128	S-Adenosyl-L-methionine + norcoclaurine	(S)-norcoclaurine and (R)-norcoclaurine	Coptis japonica	S-Adenosyl-L-homocysteine + ?	-	?	6898