1.4.3.3 (1R)-1-(2-naphthyl)ethylamine + H2O + O2 substrate of mutant Y228L/F242I/R283G Sus scrofa 1-(naphthalen-2-yl)ethan-1-one + NH3 + H2O2 - ? 460265 1.4.3.3 (1R)-1-phenylethan-1-amine + H2O + O2 no substrate of wild-type Sus scrofa 1-phenylethan-1-one + NH3 + H2O2 - ? 460266 1.4.3.3 (1R)-1-phenylethan-1-amine + H2O + O2 no substrate of wild-type, but mutant Y228L/R283G Sus scrofa 1-phenylethan-1-one + NH3 + H2O2 - ? 460266 1.4.3.3 (1R)-1-phenylpropan-1-amine + H2O + O2 mutant Y228L/R283G, 109% of the activity with (1R)-1-phenylethan-1-amine Sus scrofa 1-phenylpropan-1-one + NH3 + H2O2 - ? 460267 1.4.3.3 (R)-alpha-methylbenzylamine + H2O + O2 substrate of mutant Y228L/R283G, the neutral amine is the substrate Sus scrofa alpha-methylbenzaldehyde + NH3 + H2O2 - ? 460338 1.4.3.3 (RS)-1-(4-chlorophenyl)-1-phenylmethanamine + H2O + O2 no substrate of wild-type Sus scrofa (4-chlorophenyl)(phenyl)methanone + NH3 + H2O2 - ? 460347 1.4.3.3 1,1-diphenylmethanamine + H2O + O2 no substrate of wild-type Sus scrofa diphenylmethanone + NH3 + H2O2 - ? 460383 1.4.3.3 1-(4-fluorophenyl)ethan-1-amine + H2O + O2 mutant Y228L/R283G, 22.7% of the activity with (1R)-1-phenylethan-1-amine Sus scrofa 1-phenylethan-1-one + NH3 + H2O2 - ? 460393 1.4.3.3 3,4-dihydroxy-D-phenylalanine + H2O + O2 - Homo sapiens 3,4-dihydroxyphenylpyruvate + NH3 + H2O2 - ? 395680 1.4.3.3 4-fluoro-D-Phe + H2O + O2 82% activity compared to D-Met uncultured bacterium 4-fluorophenylpyruvate + NH3 + H2O2 - ? 440857 1.4.3.3 4-fluoro-DL-phenylalanine + H2O + O2 81% activity compared to D-methionine Glutamicibacter protophormiae 4-fluoro-phenylpyruvate + NH3 + H2O2 - ? 395855 1.4.3.3 a D-amino acid + H2O + O2 - Rattus norvegicus a 2-oxo acid + NH3 + H2O2 - ? 402393 1.4.3.3 a D-amino acid + H2O + O2 D-amino-acid oxidase catalyzes the oxidative deamination of D-amino acids, stereoisomers of the naturally occurring L-amino acids Rattus norvegicus a 2-oxo acid + NH3 + H2O2 - ? 402393 1.4.3.3 alanine + H2O + O2 - Homo sapiens pyruvate + NH3 + H2O2 - ? 396361 1.4.3.3 cephalosporin C - Trigonopsis variabilis alpha-ketoadipinyl-7-aminocephalosporanic acid - ? 376467 1.4.3.3 cephalosporin C + H2O + O2 - Sus scrofa 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Komagataella pastoris 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Rhodotorula toruloides 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Rhodotorula toruloides 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ir 259063 1.4.3.3 cephalosporin C + H2O + O2 - Trigonopsis variabilis 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - [Candida] boidinii 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Rubrobacter xylanophilus 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Mycobacterium leprae 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Glutamicibacter protophormiae 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Fusarium solani 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Cyprinus carpio 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Homo sapiens 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Rasamsonia emersonii 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 1% of the activity with D-Ala Fusarium oxysporum 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 1% of the activity with D-Met Acrostalagmus luteoalbus 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 13% of the activity with D-Val Trigonopsis variabilis 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 2% of the activity with D-Met Rhodotorula toruloides 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 14% activity compared to D-alanine Trigonopsis variabilis 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 36% activity compared to D-alanine Rhodotorula toruloides 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 - Trigonopsis variabilis CBS 4095 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 - ? 259063 1.4.3.3 cephalosporin C + H2O + O2 conversion of cephalosporin C to 7-aminocephalosporanic acid and spontaneous decarboxylation of oxoadipyl-7-amino cephalosporanic acid is promoted by the H2O2 formed in the oxidase reaction of TvDAO Trigonopsis variabilis 7-aminocephalosporanic acid + ? + H2O2 - ? 414430 1.4.3.3 D-1-naphthyl-alanine + H2O + O2 - Rhodotorula toruloides ? - ? 396818 1.4.3.3 D-1-naphthyl-glycine + H2O + O2 - Rhodotorula toruloides ? - ? 396819 1.4.3.3 D-2-aminobutyrate + H2O + O2 - Sus scrofa 2-oxobutyrate + NH3 + H2O2 - ? 259039 1.4.3.3 D-2-chloro-phenylglycine + H2O + O2 - Rhodotorula toruloides (2-chlorophenyl)acetic acid + NH3 + H2O2 - ? 396821 1.4.3.3 D-2-fluoro-phenylglycine + H2O + O2 - Rhodotorula toruloides (2-fluorophenyl)acetic acid + NH3 + H2O2 - ? 396822 1.4.3.3 D-2-naphthyl-alanine + H2O + O2 - Rhodotorula toruloides ? - ? 396823 1.4.3.3 D-2-naphthyl-glycine + H2O + O2 - Rhodotorula toruloides ? - ? 396824 1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 - Trigonopsis variabilis ? - ? 386424 1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 i.e. D-Dopa Rattus norvegicus ? - ? 386424 1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 D-Dopa undergoes unidirectional chiral inversion and further suggest that D-Dopa is first oxidatively deaminated by DAAO to its alpha-keto acid and then transaminated by dopa transaminase to L-Dopa Rattus norvegicus ? - ? 386424 1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 - Homo sapiens ? + H2O2 + NH3 - ? 402564 1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 best substrate Homo sapiens ? + H2O2 + NH3 - ? 402564 1.4.3.3 D-4-chloro-phenylglycine + H2O + O2 - Rhodotorula toruloides (4-chlorophenyl)acetic acid + NH3 + H2O2 - ? 396825 1.4.3.3 D-4-fluoro-phenylglycine + H2O + O2 - Rhodotorula toruloides (4-fluorophenyl)acetic acid + NH3 + H2O2 - ? 396826 1.4.3.3 D-4-hydroxy-phenylglycine + H2O + O2 - Rhodotorula toruloides (4-hydroxyphenyl)acetic acid + NH3 + H2O2 - ? 396827 1.4.3.3 D-Ala + H2O + O2 - Homo sapiens pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Rattus norvegicus pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Sus scrofa pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Caenorhabditis elegans pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Rhodotorula toruloides pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Todarodes pacificus pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Trigonopsis variabilis pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Mus musculus pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 - Cyprinus carpio pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 best substrate Candida parapsilosis pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 best substrate Fusarium oxysporum pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 best substrate [Candida] boidinii pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 40% of the activity with D-Pro Sus scrofa pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 57% of the activity with D-Met Acrostalagmus luteoalbus pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 71% of the activity with D-Met Rhodotorula toruloides pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 97% of the activity with D-Val Trigonopsis variabilis pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 104% activity compared to D-Ser Rhodotorula toruloides pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 165% activity compared to D-Ser Sus scrofa pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-Ala + H2O + O2 1.6% activity compared to D-Val Rubrobacter xylanophilus pyruvate + NH3 + H2O2 - ? 289401 1.4.3.3 D-alanine + 2,6-dichlorophenolindophenol + H2O - Sus scrofa pyruvate + reduced 2,6-dichlorophenolindophenol + H2O2 - r 451601 1.4.3.3 D-alanine + H2O + O2 - Homo sapiens pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Sus scrofa pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Neurospora crassa pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - [Candida] boidinii pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Candida tropicalis pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Rhodotorula toruloides pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Chlorella vulgaris pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Arion ater pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Achatina achatina pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Trigonopsis variabilis pyruvic acid + NH3 + H2O2 - ? 259038 1.4.3.3 D-alanine + H2O + O2 - Mus musculus pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Homo sapiens pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Rattus norvegicus pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Sus scrofa pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Komagataella pastoris pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Schizosaccharomyces pombe pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Rhodotorula toruloides pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Rhodotorula toruloides pyruvate + NH3 + H2O2 - ir 370910 1.4.3.3 D-alanine + H2O + O2 - Cyprinus carpio pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Oncorhynchus mykiss pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Trigonopsis variabilis pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - [Candida] boidinii pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Danio rerio pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Zea mays pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Rasamsonia emersonii pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 best substrate Cyprinus carpio pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 highly active Trigonopsis variabilis pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 100% activity Rhodotorula toruloides pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 100% activity Trigonopsis variabilis pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 enzyme works as a metabolizing agent of exogenous and endogenous free D-Ala that is abundant in aquatic invertebrates such as crustaceans and bivalve mollusks, which are potential food sources of the fish. After oral administration of D-Ala at 0.005 mM/g body weight per day to carp for 30 days, enzyme activity increases by about 8fold, 3fold, and 1.5fold in intestine, hepatopancreas, and kidney, respectively, whereas no increase is found in brain Cyprinus carpio pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 the inducible enzyme plays an important physiological role in metabolizing exogenous D-Ala that is abundant in their prey invertebrates, crustaceans, and mollusks Cyprinus carpio pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 0.26% activity compared to D-methionine Glutamicibacter protophormiae pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 recombinant maltose-binding protein-fusion DAAO Zea mays pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 5.8% activity in tadpoles compared to D-proline Xenopus laevis pyruvate + NH3 + H2O2 - ? 370910 1.4.3.3 D-alanine + H2O + O2 - Homo sapiens pyruvate + H2O2 + NH3 - ? 402567 1.4.3.3 D-alanine + H2O + O2 - Rhodotorula toruloides pyruvate + H2O2 + NH3 - ? 402567 1.4.3.3 D-alanine + oxidized methylene blue + H2O - Sus scrofa pyruvate + reduced methylene blue + H2O2 - r 451602 1.4.3.3 D-allo-isoleucine + H2O + O2 1.0% activity compared to D-methionine Glutamicibacter protophormiae ? - ? 396834 1.4.3.3 D-allo-isoleucine + H2O + O2 - Rasamsonia emersonii (3R)-3-hydroxy-2-oxobutanoate + NH3 + H2O2 - ? 460916 1.4.3.3 D-allo-threonine + H2O + O2 - Rasamsonia emersonii ? + NH3 + H2O2 - ? 460917 1.4.3.3 D-alpha-aminoadipate + H2O + O2 - Trigonopsis variabilis 2-oxoadipate + NH3 + H2O2 - ? 259066 1.4.3.3 D-amino acid + H2O + O2 - Trigonopsis variabilis 2-oxo acid + NH3 + H2O2 - ? 413341 1.4.3.3 D-amino acid + H2O + O2 via formation of an imino acid Trigonopsis variabilis 2-oxo acid + NH3 + H2O2 - ? 413341 1.4.3.3 D-amino acid + H2O + O2 - Glutamicibacter protophormiae a 2-oxo carboxylate + NH3 + H2O2 - ir 424739 1.4.3.3 D-amino acid + H2O + O2 - Mus musculus 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - Homo sapiens 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - Homo sapiens 2-oxocarboxylate + NH3 + H2O2 - ir 424740 1.4.3.3 D-amino acid + H2O + O2 - Rattus norvegicus 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - Xenopus laevis 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - Schizosaccharomyces pombe 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - [Candida] boidinii 2-oxocarboxylate + NH3 + H2O2 - ir 424740 1.4.3.3 D-amino acid + H2O + O2 - Rhodotorula toruloides 2-oxocarboxylate + NH3 + H2O2 - ir 424740 1.4.3.3 D-amino acid + H2O + O2 - Trigonopsis variabilis 2-oxocarboxylate + NH3 + H2O2 - ? 424740 1.4.3.3 D-amino acid + H2O + O2 - Trigonopsis variabilis 2-oxocarboxylate + NH3 + H2O2 - ir 424740 1.4.3.3 D-Arg + H2O + O2 - Sus scrofa 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 2% of the activity with D-Met Rhodotorula toruloides 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 25% of the activity with D-Ala Candida parapsilosis 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 4% of the activity with D-Pro Sus scrofa 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 43% of the activity with D-Val Trigonopsis variabilis 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 7% of the activity with D-Ala Fusarium oxysporum 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 1.1% activity compared to D-Val Rubrobacter xylanophilus 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 76% activity compared to D-Met uncultured bacterium 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 372827 1.4.3.3 D-Arg + H2O + O2 - Sus scrofa 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 388433 1.4.3.3 D-Arg + H2O + O2 - Caenorhabditis elegans 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 388433 1.4.3.3 D-arginine + H2O + O2 - Rhodotorula toruloides 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 259065 1.4.3.3 D-arginine + H2O + O2 - Trigonopsis variabilis 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 259065 1.4.3.3 D-arginine + H2O + O2 19% activity compared to D-alanine Rhodotorula toruloides 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 259065 1.4.3.3 D-arginine + H2O + O2 42% activity compared to D-alanine Trigonopsis variabilis 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 259065 1.4.3.3 D-arginine + H2O + O2 80% activity compared to D-methionine Glutamicibacter protophormiae 5-guanidino-2-oxopentanoic acid + NH3 + H2O2 - ? 259065 1.4.3.3 D-arginine + H2O + O2 - Trigonopsis variabilis 5-guanidino-2-oxopentanoate + NH3 + H2O2 - r 396839 1.4.3.3 D-arginine + H2O + O2 - Rhodotorula toruloides 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 396839 1.4.3.3 D-arginine + H2O + O2 - Rasamsonia emersonii 5-guanidino-2-oxopentanoate + NH3 + H2O2 - ? 396839 1.4.3.3 D-Asn + H2O + O2 - Sus scrofa 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 - Trigonopsis variabilis 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 - Rhodotorula toruloides 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 0.18% of the activity with D-Ala [Candida] boidinii 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 2% of the activity with D-Ala Candida parapsilosis 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 3% of the activity with D-Ala Fusarium oxysporum 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 40% of the activity with D-Met Rhodotorula toruloides 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asn + H2O + O2 65% of the activity with D-Val Trigonopsis variabilis 2-oxosuccinamate + NH3 + H2O2 - ? 372829 1.4.3.3 D-Asp + H2O + O2 - Homo sapiens oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-Asp + H2O + O2 - Sus scrofa oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-Asp + H2O + O2 - Rhodotorula toruloides oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-Asp + H2O + O2 7% of the activity with D-Met Acrostalagmus luteoalbus oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-Asp + H2O + O2 38.6% activity compared to D-Ser Sus scrofa oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-Asp + H2O + O2 5.5% activity compared to D-Ser Rhodotorula toruloides oxaloacetate + NH3 + H2O2 - ? 372831 1.4.3.3 D-asparagine + H2O + O2 - [Candida] boidinii 2-oxosuccinamic acid + NH3 + H2O2 - ? 259060 1.4.3.3 D-asparagine + H2O + O2 - Rhodotorula toruloides 2-oxosuccinamic acid + NH3 + H2O2 - ? 259060 1.4.3.3 D-asparagine + H2O + O2 - Chlorella vulgaris 2-oxosuccinamic acid + NH3 + H2O2 - ? 259060 1.4.3.3 D-asparagine + H2O + O2 38% activity compared to D-alanine Rhodotorula toruloides 2-oxosuccinamic acid + NH3 + H2O2 - ? 259060 1.4.3.3 D-asparagine + H2O + O2 67% activity compared to D-alanine Trigonopsis variabilis 2-oxosuccinamic acid + NH3 + H2O2 - ? 259060 1.4.3.3 D-aspartate + H2O + O2 - Homo sapiens oxaloacetate + NH3 + H2O2 - ? 258958 1.4.3.3 D-aspartate + H2O + O2 - Rhodotorula toruloides oxaloacetate + NH3 + H2O2 - ? 258958 1.4.3.3 D-aspartate + H2O + O2 2% activity compared to D-alanine Trigonopsis variabilis oxaloacetate + NH3 + H2O2 - ? 258958 1.4.3.3 D-aspartate + H2O + O2 3% activity compared to D-alanine Rhodotorula toruloides oxaloacetate + NH3 + H2O2 - ? 258958 1.4.3.3 D-aspartate + H2O + O2 1.0% activity in tadpoles compared to D-proline Xenopus laevis oxaloacetate + NH3 + H2O2 - ? 258958 1.4.3.3 D-aspartate + H2O + O2 - Homo sapiens ? - ? 396843 1.4.3.3 D-aspartate + H2O + O2 recombinant maltose-binding protein-fusion DAAO Zea mays ? + NH3 + H2O2 - ? 404783 1.4.3.3 D-aspartic acid + H2O + O2 weak activity Sus scrofa oxaloacetate + NH3 + H2O2 - ? 258996 1.4.3.3 D-citrulline + H2O + O2 - Trigonopsis variabilis 2-oxo-5-ureidopentanoic acid + NH3 + H2O2 - ? 259064 1.4.3.3 D-citrulline + H2O + O2 - Trigonopsis variabilis 2-oxo-5-ureidopentanoate + NH3 + H2O2 - r 451604 1.4.3.3 D-cycloserine + H2O + O2 - Homo sapiens ? + NH3 + H2O2 - ? 460922 1.4.3.3 D-Cys + H2O + O2 1% of the activity with D-Met Rhodotorula toruloides 2-oxo-3-sulfanylpropionate + NH3 + H2O2 - ? 372834 1.4.3.3 D-cysteine + H2O + O2 - Candida tropicalis 2-oxo-3-thiopropionic acid + NH3 + H2O2 - ? 259055 1.4.3.3 D-cysteine + H2O + O2 - Rhodotorula toruloides 2-oxo-3-thiopropionic acid + NH3 + H2O2 - ? 259055 1.4.3.3 D-cysteine + H2O + O2 18% activity compared to D-alanine Rhodotorula toruloides 2-oxo-3-thiopropionic acid + NH3 + H2O2 - ? 259055 1.4.3.3 D-cysteine + H2O + O2 9% activity compared to D-alanine Trigonopsis variabilis 2-oxo-3-thiopropionic acid + NH3 + H2O2 - ? 259055 1.4.3.3 D-cysteine + H2O + O2 - Homo sapiens 2-oxo-3-sulfanylpropionate + NH3 + H2O2 - ? 460923 1.4.3.3 D-DOPA + H2O + O2 - Homo sapiens 3,4-dihydroxyphenylpyruvic acid + NH3 + H2O2 - ? 396848 1.4.3.3 D-DOPA + H2O + O2 the maximal velocity for oxidation of D-DOPA is much greater than for D-serine Homo sapiens 3,4-dihydroxyphenylpyruvic acid + NH3 + H2O2 - ? 396848 1.4.3.3 D-DOPA + H2O + O2 - Homo sapiens 3,4-dihydroxyphenylpyruvate + NH3 + H2O2 - ? 460924 1.4.3.3 D-ethionine + H2O + O2 - Neurospora crassa 4-ethylsulfanyl-2-oxobutyric acid + NH3 + H2O2 - ? 259059 1.4.3.3 D-ethionine + H2O + O2 - Trigonopsis variabilis 4-ethylsulfanyl-2-oxobutyric acid + NH3 + H2O2 - ? 259059 1.4.3.3 D-Gln + H2O + O2 - Sus scrofa 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 1% of the activity with D-Pro Sus scrofa 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 15% of the activity with D-Ala Fusarium oxysporum 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 5% of the activity with D-Ala Candida parapsilosis 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 51% of the activity with D-Met Acrostalagmus luteoalbus 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 53% of the activity with D-Met Rhodotorula toruloides 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 81% of the activity with D-Val Trigonopsis variabilis 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Gln + H2O + O2 1.0% activity compared to D-Val Rubrobacter xylanophilus 2-oxoglutaramate + NH3 + H2O2 - ? 372861 1.4.3.3 D-Glu + H2O + O2 - Sus scrofa alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 - Rhodotorula toruloides alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 10% of the activity with D-Met Acrostalagmus luteoalbus alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 4% of the activity with D-Met Rhodotorula toruloides alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 4% of the activity with D-Pro Sus scrofa alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 54% of the activity with D-Ala Candida parapsilosis alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 9% of the activity with D-Val Trigonopsis variabilis alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-Glu + H2O + O2 5.1% activity compared to D-Val Rubrobacter xylanophilus alpha-ketoglutarate + NH3 + H2O2 - ? 372862 1.4.3.3 D-glufosinate + H2O + O2 - Rhodotorula toruloides ? - ir 426216 1.4.3.3 D-glutamate + H2O + O2 - Rhodotorula toruloides 2-oxoglutarate + NH3 + H2O2 - ? 258959 1.4.3.3 D-glutamate + H2O + O2 - Homo sapiens 2-oxoglutarate + NH3 + H2O2 - ? 258959 1.4.3.3 D-glutamate + H2O + O2 - Rasamsonia emersonii 2-oxoglutarate + NH3 + H2O2 - ? 258959 1.4.3.3 D-glutamate + H2O + O2 - Rhodotorula toruloides alpha-ketoglutarate + NH3 + H2O2 - ? 396880 1.4.3.3 D-glutamate + H2O + O2 3% activity compared to D-alanine Rhodotorula toruloides alpha-ketoglutarate + NH3 + H2O2 - ? 396880 1.4.3.3 D-glutamate + H2O + O2 9% activity compared to D-alanine Trigonopsis variabilis alpha-ketoglutarate + NH3 + H2O2 - ? 396880 1.4.3.3 D-glutamic acid + H2O + O2 - Chlorella vulgaris alpha-ketoglutarate + NH3 + H2O2 - ? 259061 1.4.3.3 D-glutamine + H2O + O2 - Candida tropicalis 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-glutamine + H2O + O2 - Rhodotorula toruloides 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-glutamine + H2O + O2 - Chlorella vulgaris 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-glutamine + H2O + O2 - Rasamsonia emersonii 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-glutamine + H2O + O2 58% activity compared to D-alanine Rhodotorula toruloides 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-glutamine + H2O + O2 78% activity compared to D-alanine Trigonopsis variabilis 2-oxoglutaramate + NH3 + H2O2 - ? 259057 1.4.3.3 D-His + H2O + O2 - Sus scrofa 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 - Caenorhabditis elegans 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 - Todarodes pacificus 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 14% of the activity with D-Ala Fusarium oxysporum 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 3% of the activity with D-Pro Sus scrofa 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 4% of the activity with D-Ala Candida parapsilosis 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 58% of the activity with D-Met Rhodotorula toruloides 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 88% of the activity with D-Val Trigonopsis variabilis 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 12% activity compared to D-Met uncultured bacterium 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-His + H2O + O2 3.6% activity compared to D-Val Rubrobacter xylanophilus 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 372919 1.4.3.3 D-histidine + H2O + O2 - Sus scrofa 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 - Candida tropicalis 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 - Rhodotorula toruloides 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 - Chlorella vulgaris 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 - Trigonopsis variabilis 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 5.9% activity compared to D-methionine Glutamicibacter protophormiae 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 60% activity compared to D-alanine Rhodotorula toruloides 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 69% activity compared to D-alanine Trigonopsis variabilis 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2 - ? 259046 1.4.3.3 D-histidine + H2O + O2 - Rasamsonia emersonii 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 - ? 460953 1.4.3.3 D-homo-phenylalanine + H2O + O2 - Rhodotorula toruloides ? - ? 396886 1.4.3.3 D-Ile + H2O + O2 - Sus scrofa 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 - Cyprinus carpio 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 15% of the activity with D-Met Acrostalagmus luteoalbus 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 19% of the activity with D-Ala Fusarium oxysporum 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 35% of the activity with D-Pro Sus scrofa 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 56% of the activity with D-Met Rhodotorula toruloides 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 76% of the activity with D-Val Trigonopsis variabilis 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-Ile + H2O + O2 26.7% activity compared to D-Val Rubrobacter xylanophilus 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372925 1.4.3.3 D-isoleucine + H2O + O2 - Sus scrofa 3-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259047 1.4.3.3 D-isoleucine + H2O + O2 - Candida tropicalis 3-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259047 1.4.3.3 D-isoleucine + H2O + O2 - Rhodotorula toruloides 3-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259047 1.4.3.3 D-isoleucine + H2O + O2 - Chlorella vulgaris 3-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259047 1.4.3.3 D-isoleucine + H2O + O2 - Trigonopsis variabilis 3-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259047 1.4.3.3 D-isoleucine + H2O + O2 - Rhodotorula toruloides 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 396891 1.4.3.3 D-isoleucine + H2O + O2 - Rasamsonia emersonii 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 396891 1.4.3.3 D-isoleucine + H2O + O2 60% activity compared to D-alanine Rhodotorula toruloides 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 396891 1.4.3.3 D-isoleucine + H2O + O2 69% activity compared to D-alanine Trigonopsis variabilis 3-methyl-2-oxopentanoate + NH3 + H2O2 - ? 396891 1.4.3.3 D-kynurenine + H2O + O2 - Homo sapiens kynurenic acid + NH3 + H2O2 - ? 424758 1.4.3.3 D-kynurenine + H2O + O2 - Homo sapiens kynurenate + NH3 + H2O2 - ? 460956 1.4.3.3 D-kynurenine + NH3 + H2O2 - Mus musculus kynurenic acid + NH3 + H2O2 - ? 440206 1.4.3.3 D-Leu + H2O + O2 - Sus scrofa 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 - Cyprinus carpio 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 21% of the activity with D-Pro Sus scrofa 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 29% of the activity with D-Ala Fusarium oxysporum 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 32% of the activity with D-Val Trigonopsis variabilis 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 42% of the activity with D-Met Acrostalagmus luteoalbus 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 57% of the activity with D-Met Rhodotorula toruloides 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 7% of the activity with D-Ala [Candida] boidinii 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 92% of the activity with D-Ala Candida parapsilosis 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 26% activity compared to D-Met uncultured bacterium 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 27.2% activity compared to D-Val Rubrobacter xylanophilus 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 372934 1.4.3.3 D-Leu + H2O + O2 - Trigonopsis variabilis 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 426226 1.4.3.3 D-leucine + H2O + O2 - Sus scrofa 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Neurospora crassa 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - [Candida] boidinii 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Candida tropicalis 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Rhodotorula toruloides 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Chlorella vulgaris 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Trigonopsis variabilis 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 best substrate Chlorella vulgaris 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 12% activity compared to D-methionine Glutamicibacter protophormiae 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 37% activity compared to D-alanine Trigonopsis variabilis 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 86% activity compared to D-alanine Rhodotorula toruloides 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 2.3% activity in tadpoles compared to D-proline Xenopus laevis 4-methyl-2-oxopentanoic acid + NH3 + H2O2 - ? 259052 1.4.3.3 D-leucine + H2O + O2 - Rasamsonia emersonii 4-methyl-2-oxopentanoate + NH3 + H2O2 - ? 460959 1.4.3.3 D-Lys + H2O + O2 17% of the activity with D-Val Trigonopsis variabilis ? - ? 372937 1.4.3.3 D-Lys + H2O + O2 2% of the activity with D-Pro Sus scrofa ? - ? 372937 1.4.3.3 D-Lys + H2O + O2 25% of the activity with D-Ala Candida parapsilosis ? - ? 372937 1.4.3.3 D-Lys + H2O + O2 5% of the activity with D-Met Rhodotorula toruloides ? - ? 372937 1.4.3.3 D-Lys + H2O + O2 - Cyprinus carpio ? + NH3 + H2O2 - ? 372938 1.4.3.3 D-Lys + H2O + O2 - Sus scrofa 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 388458 1.4.3.3 D-Lys + H2O + O2 - Trigonopsis variabilis 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 388458 1.4.3.3 D-Lys + H2O + O2 2.4% activity compared to D-Val Rubrobacter xylanophilus 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 388458 1.4.3.3 D-Lys + H2O + O2 90% activity compared to D-Met uncultured bacterium 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 388458 1.4.3.3 D-lysine + H2O + O2 - Rhodotorula toruloides 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 396897 1.4.3.3 D-lysine + H2O + O2 poor substrate Trigonopsis variabilis 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 396897 1.4.3.3 D-lysine + H2O + O2 7% activity compared to D-alanine Trigonopsis variabilis 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 396897 1.4.3.3 D-lysine + H2O + O2 8% activity compared to D-alanine Rhodotorula toruloides 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 396897 1.4.3.3 D-lysine + H2O + O2 99% activity compared to D-methionine Glutamicibacter protophormiae 6-amino-2-oxohexanoic acid + NH3 + H2O2 - ? 396897 1.4.3.3 D-lysine + H2O + O2 - Rhodotorula toruloides 6-amino-2-oxohexanoate + NH3 + H2O2 - ? 460961 1.4.3.3 D-Met + H2O + O2 - Sus scrofa 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 - Trigonopsis variabilis 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 - Rhodotorula toruloides 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 best substrate Rhodotorula toruloides 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 best substrate Acrostalagmus luteoalbus 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 100% activity uncultured bacterium 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 14% of the activity with D-Ala [Candida] boidinii 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 28% of the activity with D-Ala Fusarium oxysporum 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 75% of the activity with D-Pro Sus scrofa 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 78% of the ativity with D-Val Trigonopsis variabilis 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 2.0% activity compared to D-Val Rubrobacter xylanophilus 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 372956 1.4.3.3 D-Met + H2O + O2 best substrate Trigonopsis variabilis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 426235 1.4.3.3 D-methionine + 2,6-dichloroindophenol - Trigonopsis variabilis 4-methylsulfanyl-2-oxobutanoate + reduced 2,6-dichloroindophenol - ? 414504 1.4.3.3 D-methionine + 2,6-dichloroindophenol - Trigonopsis variabilis ATCC 10679 4-methylsulfanyl-2-oxobutanoate + reduced 2,6-dichloroindophenol - ? 414504 1.4.3.3 D-methionine + 2,6-dichlorophenolindophenol - Trigonopsis variabilis ? - ? 388467 1.4.3.3 D-methionine + 2,6-dichlorophenolindophenol + H2O - Trigonopsis variabilis ? - ? 396915 1.4.3.3 D-methionine + H2O + 2,6-dichloroindophenol - Trigonopsis variabilis ? - ? 404880 1.4.3.3 D-methionine + H2O + O2 - Sus scrofa 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Neurospora crassa 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - [Candida] boidinii 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Rhodotorula toruloides 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Chlorella vulgaris 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Arion ater 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Achatina achatina 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 - Trigonopsis variabilis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 best substrate Trigonopsis variabilis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 best substrate [Candida] boidinii 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 100% activity Glutamicibacter protophormiae 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 113% activity compared to D-alanine Rhodotorula toruloides 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 77% activity compared to D-alanine Trigonopsis variabilis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 by far best substrate Trigonopsis variabilis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 7.6% activity in tadpoles compared to D-proline Xenopus laevis 4-methylthio-2-oxobutanoic acid + NH3 + H2O2 - ? 259043 1.4.3.3 D-methionine + H2O + O2 highly active Trigonopsis variabilis 4-methylthio-2-oxobutanoate + NH3 + H2O2 - ? 396918 1.4.3.3 D-methionine + H2O + O2 - Trigonopsis variabilis 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 - Rhodotorula toruloides 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 - Rasamsonia emersonii 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 with 6-dichloroindophenol as electron acceptor Trigonopsis variabilis 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 - Trigonopsis variabilis ATCC 10679 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 with 6-dichloroindophenol as electron acceptor Trigonopsis variabilis ATCC 10679 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 - ? 413346 1.4.3.3 D-methionine + H2O + O2 - Glutamicibacter protophormiae 2-oxo-4-methylthiobutyric acid + NH3 + H2O2 - ir 426237 1.4.3.3 D-naphthylalanine + H2O + O2 - Rhodotorula toruloides naphthylpyruvate + NH3 + H2O2 - ? 396920 1.4.3.3 D-norleucine + H2O + O2 - Sus scrofa 2-oxohexanoate + NH3 + H2O2 - ? 259041 1.4.3.3 D-norleucine + H2O + O2 - Neurospora crassa 2-oxohexanoate + NH3 + H2O2 - ? 259041 1.4.3.3 D-norleucine + H2O + O2 - Rhodotorula toruloides 2-oxohexanoate + NH3 + H2O2 - ? 259041 1.4.3.3 D-norvaline + H2O + O2 - Sus scrofa 2-oxopentanoate + NH3 + H2O2 - ? 259040 1.4.3.3 D-norvaline + H2O + O2 - Neurospora crassa 2-oxopentanoate + NH3 + H2O2 - ? 259040 1.4.3.3 D-norvaline + H2O + O2 - Rhodotorula toruloides 2-oxopentanoate + NH3 + H2O2 - ? 259040 1.4.3.3 D-Orn + H2O + O2 34% activity compared to D-Met uncultured bacterium 5-amino-2-oxopentanoate + NH3 + H2O2 - ? 441258 1.4.3.3 D-ornithine + H2O + O2 - Sus scrofa 5-amino-2-oxopentanoate + NH3 + H2O2 - ? 259045 1.4.3.3 D-ornithine + H2O + O2 15% activity compared to D-methionine Glutamicibacter protophormiae 5-amino-2-oxopentanoate + NH3 + H2O2 - ? 259045 1.4.3.3 D-Phe + H2O + O2 - Sus scrofa phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 - Caenorhabditis elegans phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 - Todarodes pacificus phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 - Trigonopsis variabilis phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 - Rhodotorula toruloides phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 - Cyprinus carpio phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 1.5% of the activity with D-Ala [Candida] boidinii phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 19% of the activity with D-Ala Candida parapsilosis phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 36% of the activity with D-Val Trigonopsis variabilis phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 41% of the activity with D-Ala Fusarium oxysporum phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 50% of the activity with D-Met Acrostalagmus luteoalbus phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 79% of the activity with D-Met Rhodotorula toruloides phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 84% of the activity with D-Pro Sus scrofa phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 2.1% activity compared to D-Val Rubrobacter xylanophilus phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-Phe + H2O + O2 51% activity compared to D-Met uncultured bacterium phenylpyruvate + NH3 + H2O2 - ? 372957 1.4.3.3 D-phenylalanine + H2O + O2 - Sus scrofa phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Neurospora crassa phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - [Candida] boidinii phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Rhodotorula toruloides phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Chlorella vulgaris phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Cyprinus carpio phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Oncorhynchus mykiss phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Arion ater phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Achatina achatina phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Trigonopsis variabilis phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 activity of the DAAO after incubation in water-insoluble ionic liquids is higher than in water-soluble ones Trigonopsis variabilis phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 activity of the DAAO after incubation in water-insoluble ionic liquids is higher than in water-soluble ones Trigonopsis variabilis CBS 4095 phenylpyruvic acid + NH3 + H2O2 - ? 259048 1.4.3.3 D-phenylalanine + H2O + O2 - Homo sapiens phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Rattus norvegicus phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Rhodotorula toruloides phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Trigonopsis variabilis phenylpyruvate + NH3 + H2O2 - r 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Trigonopsis variabilis phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Rasamsonia emersonii phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 second best substrate Xenopus laevis phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 44% activity compared to D-alanine Trigonopsis variabilis phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 54% activity compared to D-methionine Glutamicibacter protophormiae phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 80% activity compared to D-methionine Glutamicibacter protophormiae phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 94% activity compared to D-alanine Rhodotorula toruloides phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 conversion of D-phenylalanine to 99.0% phenylpyruvate within 100 min Komagataella pastoris phenylpyruvate + NH3 + H2O2 - ? 394824 1.4.3.3 D-phenylalanine + H2O + O2 - Rhodotorula toruloides ? - ? 396924 1.4.3.3 D-phenylglycine + H2O + O2 - Sus scrofa benzoylformic acid + NH3 + H2O2 - ? 396925 1.4.3.3 D-phenylglycine + H2O + O2 - Trigonopsis variabilis benzoylformic acid + NH3 + H2O2 - ? 396925 1.4.3.3 D-phenylglycine + H2O + O2 - Rhodotorula toruloides benzoylformic acid + NH3 + H2O2 - ? 396925 1.4.3.3 D-Pro + H2O + O2 - Homo sapiens 2-oxopentanoate + NH3 + H2O2 - ? 372961 1.4.3.3 D-Pro + H2O + O2 - Sus scrofa 2-oxopentanoate + NH3 + H2O2 - ? 372961 1.4.3.3 D-Pro + H2O + O2 - Rhodotorula toruloides 2-oxopentanoate + NH3 + H2O2 - ? 372961 1.4.3.3 D-Pro + H2O + O2 - Cyprinus carpio 2-oxopentanoate + NH3 + H2O2 - ? 372961 1.4.3.3 D-Pro + H2O + O2 - Sus scrofa 2-oxopentanoic acid + NH3 + H2O2 - ? 372962 1.4.3.3 D-Pro + H2O + O2 - Rhodotorula toruloides 2-oxopentanoic acid + NH3 + H2O2 - ? 372962 1.4.3.3 D-Pro + H2O + O2 - Mus musculus 2-oxopentanoic acid + NH3 + H2O2 - ? 372962 1.4.3.3 D-proline + H2O + O2 - Homo sapiens 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Rattus norvegicus 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Sus scrofa 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - [Candida] boidinii 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Candida tropicalis 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Rhodotorula toruloides 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Chlorella vulgaris 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Arion ater 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Achatina achatina 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Cyprinus carpio 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 best substrate Sus scrofa 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 best substrate Cyprinus carpio 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 best substrate Oncorhynchus mykiss 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 1.4% of the activity with D-Ala [Candida] boidinii 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 22% of the activity with D-Ala Fusarium oxysporum 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 25% of the activity with D-Val Trigonopsis variabilis 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 4% of the activity with D-Met Acrostalagmus luteoalbus 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 41% of the activity with D-Ala Candida parapsilosis 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 57% of the activity with D-Met Rhodotorula toruloides 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 0.25% activity compared to D-methionine Glutamicibacter protophormiae 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 21% activity compared to D-alanine Trigonopsis variabilis 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 46% activity compared to D-alanine Rhodotorula toruloides 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 1.1% activity in tadpoles compared to D-proline Xenopus laevis 2-oxopentanoic acid + NH3 + H2O2 - ? 258961 1.4.3.3 D-proline + H2O + O2 - Trigonopsis variabilis 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-proline + H2O + O2 - Homo sapiens 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-proline + H2O + O2 best substrate Todarodes pacificus 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-proline + H2O + O2 best substrate Sus scrofa 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-proline + H2O + O2 best substrate Homo sapiens 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-proline + H2O + O2 best substrate, 100% activity in tadpoles and adults Xenopus laevis 2-oxopentanoate + NH3 + H2O2 - ? 372964 1.4.3.3 D-Ser + H2O + O2 - Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 - Sus scrofa 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 - Caenorhabditis elegans 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 - Rhodotorula toruloides 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 - Cyprinus carpio 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 100% activity Sus scrofa 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 100% activity Rhodotorula toruloides 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 18% of the activity with D-Ala Fusarium oxysporum 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 18% of the activity with D-Pro Sus scrofa 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 22% of the activity with D-Val Trigonopsis variabilis 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 32% of the activity with D-Ala [Candida] boidinii 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 41% of the activity with D-Met Rhodotorula toruloides 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 6% of the activity with D-Ala Candida parapsilosis 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 9% of the activity with D-Met Acrostalagmus luteoalbus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 1.3% activity compared to D-Val Rubrobacter xylanophilus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 372973 1.4.3.3 D-Ser + H2O + O2 - Trigonopsis variabilis 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 426247 1.4.3.3 D-serine + H2O + O2 - Gallus gallus 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Mus musculus 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Homo sapiens 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Rattus norvegicus 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Sus scrofa 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - [Candida] boidinii 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Candida tropicalis 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Rhodotorula toruloides 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Chlorella vulgaris 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Trigonopsis variabilis 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 astroglial enzyme plays an important role in metabolizing a neuromodulator, D-serine Mus musculus 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 23% activity compared to D-alanine Trigonopsis variabilis 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 49% activity compared to D-alanine Rhodotorula toruloides 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 7.6% activity in tadpoles compared to D-proline Xenopus laevis 2-oxo-3-hydroxypropionic acid + NH3 + H2O2 - ? 259054 1.4.3.3 D-serine + H2O + O2 - Mus musculus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Rattus norvegicus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Trigonopsis variabilis 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Sus scrofa 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Rasamsonia emersonii 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 poor substrate Trigonopsis variabilis 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 D-serine, an endogenous agonist of the N-methyl-D-aspartate, NMDA, receptors, is effective in the treatment of schizophrenia. However, orally administered D-serine is metabolized substantially by D-amino acid oxidase diminishing its oral bioavailability Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 high doses of D-serine attenuate both amphetamine-induced psychomotor activity and dopamine release and also improve performance in novel object recognition Rattus norvegicus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 metabolizaation of the N-methyl D-aspartate receptor co-agonist Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 physiological effects of D-serine, overview Mus musculus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 the apoprotein form of hDAAO binds the substrate D-serine, which increases FAD binding thus increasing the amount of active holoenzyme in solution Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 low catalytic efficiency and substrate affinity on the physiological substrate D-serine Homo sapiens 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Mus musculus C57/BL6J 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 physiological effects of D-serine, overview Mus musculus C57/BL6J 2-oxo-3-hydroxypropionate + NH3 + H2O2 - ? 396931 1.4.3.3 D-serine + H2O + O2 - Rattus norvegicus 3-hydroxypyruvate + NH3 + H2O2 - ? 396932 1.4.3.3 D-serine + H2O + O2 - Sus scrofa 3-hydroxypyruvate + NH3 + H2O2 - r 396932 1.4.3.3 D-serine + H2O + O2 - Trigonopsis variabilis 3-hydroxypyruvate + NH3 + H2O2 - r 396932 1.4.3.3 D-serine + H2O + O2 - Homo sapiens 3-hydroxypyruvate + NH3 + H2O2 - ? 396932 1.4.3.3 D-serine + H2O + O2 - Mus musculus ? + NH3 + H2O2 - ? 402586 1.4.3.3 D-serine + H2O + O2 - Homo sapiens ? - ? 404906 1.4.3.3 D-serine + H2O + O2 - Homo sapiens 2-oxo-3-hydroxypropanoate + NH3 + H2O2 - ? 460975 1.4.3.3 D-serine + H2O + O2 - Homo sapiens oxo-3-hydroxypropionate + NH3 + H2O2 - ? 460976 1.4.3.3 D-Thr + H2O + O2 - Sus scrofa 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 426253 1.4.3.3 D-Thr + H2O + O2 - Trigonopsis variabilis 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 426253 1.4.3.3 D-Thr + H2O + O2 11.5% activity compared to D-Val Rubrobacter xylanophilus 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 426253 1.4.3.3 D-threonine + H2O + O2 - [Candida] boidinii 2-oxo-3-hydroxybutyric acid + NH3 + H2O2 - ? 259062 1.4.3.3 D-threonine + H2O + O2 - Rhodotorula toruloides 2-oxo-3-hydroxybutyric acid + NH3 + H2O2 - ? 259062 1.4.3.3 D-threonine + H2O + O2 - Chlorella vulgaris 2-oxo-3-hydroxybutyric acid + NH3 + H2O2 - ? 259062 1.4.3.3 D-threonine + H2O + O2 18% activity compared to D-alanine Rhodotorula toruloides 2-oxo-3-hydroxybutyric acid + NH3 + H2O2 - ? 259062 1.4.3.3 D-threonine + H2O + O2 2% activity compared to D-alanine Trigonopsis variabilis 2-oxo-3-hydroxybutyric acid + NH3 + H2O2 - ? 259062 1.4.3.3 D-threonine + H2O + O2 poor substrate Trigonopsis variabilis 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-threonine + H2O + O2 1.2% of the activity with D-Ala [Candida] boidinii 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-threonine + H2O + O2 10% of the activity with D-Met Rhodotorula toruloides 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-threonine + H2O + O2 2% of the activity with D-Ala Fusarium oxysporum 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-threonine + H2O + O2 2% of the activity with D-Pro Sus scrofa 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-threonine + H2O + O2 4% of the activity with D-Val Trigonopsis variabilis 2-oxo-3-hydroxybutyrate + NH3 + H2O2 - ? 372979 1.4.3.3 D-Trp + H2O + O2 - Sus scrofa indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 - Trigonopsis variabilis indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 - Rhodotorula toruloides indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 14% of the activity with D-Ala Fusarium oxysporum indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 2% of the activity with D-Pro Sus scrofa indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 38% of the activity with D-val Trigonopsis variabilis indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 56% of the activity with D-Met Rhodotorula toruloides indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 9% of the activity with D-Ala Candida parapsilosis indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 1.5% activity compared to D-Val Rubrobacter xylanophilus indol-3-pyruvate + NH3 + H2O2 - ? 372981 1.4.3.3 D-Trp + H2O + O2 - Mus musculus indole-3-pyruvate + NH3 + H2O2 - ? 440207 1.4.3.3 D-tryptophan + H2O + O2 - Homo sapiens indol-3-pyruvic acid + NH3 + H2O2 - ? 259053 1.4.3.3 D-tryptophan + H2O + O2 - Sus scrofa indol-3-pyruvic acid + NH3 + H2O2 - ? 259053 1.4.3.3 D-tryptophan + H2O + O2 - Rhodotorula toruloides indol-3-pyruvic acid + NH3 + H2O2 - ? 259053 1.4.3.3 D-tryptophan + H2O + O2 - Trigonopsis variabilis indol-3-pyruvic acid + NH3 + H2O2 - ? 259053 1.4.3.3 D-tryptophan + H2O + O2 - Rattus norvegicus indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 - Rhodotorula toruloides indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 - Sus scrofa indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 - Homo sapiens indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 129% activity compared to D-alanine Trigonopsis variabilis indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 92% activity compared to D-alanine Rhodotorula toruloides indol-3-pyruvate + NH3 + H2O2 - ? 396941 1.4.3.3 D-tryptophan + H2O + O2 - Homo sapiens indole-3-pyruvic acid + NH3 + H2O2 - ? 402589 1.4.3.3 D-tryptophan + H2O + O2 - Sus scrofa indole-3-pyruvic acid + NH3 + H2O2 - ? 402589 1.4.3.3 D-tryptophan + H2O + O2 DAAO catalyzes the production of aryl hydrocarbon receptor, AHR, agonists through the enzymatic conversion of D-tryptophan to indole-3-pyruvic acid Homo sapiens indole-3-pyruvic acid + NH3 + H2O2 - ? 402589 1.4.3.3 D-tryptophan + H2O + O2 DAAO catalyzes the production of aryl hydrocarbon receptor, AHR, agonists through the enzymatic conversion of D-tryptophan to indole-3-pyruvic acid Sus scrofa indole-3-pyruvic acid + NH3 + H2O2 - ? 402589 1.4.3.3 D-Tyr + H2O + O2 - Sus scrofa 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 372982 1.4.3.3 D-Tyr + H2O + O2 - Todarodes pacificus 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 372982 1.4.3.3 D-Tyr + H2O + O2 - Cyprinus carpio 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 372982 1.4.3.3 D-Tyr + H2O + O2 11.6% activity compared to D-Met uncultured bacterium 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 372982 1.4.3.3 D-Tyr + H2O + O2 17.6% activity compared to D-Val Rubrobacter xylanophilus 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 372982 1.4.3.3 D-Tyr + H2O + O2 - Trigonopsis variabilis 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-Tyr + H2O + O2 17% of the activity with D-Val Trigonopsis variabilis 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-Tyr + H2O + O2 26% of the activity with D-Met Rhodotorula toruloides 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-Tyr + H2O + O2 4% of the activity with D-Pro Sus scrofa 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-Tyr + H2O + O2 6% of the activity with D-Ala Candida parapsilosis 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-Tyr + H2O + O2 8% of the activity with D-Ala Fusarium oxysporum 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 372983 1.4.3.3 D-tyrosine + H2O + O2 - Homo sapiens 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 - Sus scrofa 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 - Rhodotorula toruloides 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 - Chlorella vulgaris 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 - Trigonopsis variabilis 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 18% activity compared to D-alanine Rhodotorula toruloides 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 19% activity compared to D-alanine Trigonopsis variabilis 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 4.7% activity compared to D-methionine Glutamicibacter protophormiae 4-hydroxyphenylpyruvic acid + NH3 + H2O2 - ? 259049 1.4.3.3 D-tyrosine + H2O + O2 - Sus scrofa 3-(4-hydroxyphenyl)pyruvate + NH3 + H2O2 - r 451603 1.4.3.3 D-tyrosine + H2O + O2 - Homo sapiens 3-(4-hydroxyphenyl)pyruvate + NH3 + H2O2 - ? 451603 1.4.3.3 D-tyrosine + H2O + O2 - Rasamsonia emersonii 4-hydroxyphenylpyruvate + NH3 + H2O2 - ? 460983 1.4.3.3 D-Val + H2O + O2 - Sus scrofa alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 - Rhodotorula toruloides alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 - Cyprinus carpio alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 best substrate Trigonopsis variabilis alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 15% of the activity with D-Ala Candida parapsilosis alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 28% of the activity with D-Pro Sus scrofa alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 41% of the activity with D-Met Acrostalagmus luteoalbus alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 62% of the activity with D-Ala Fusarium oxysporum alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 8% of the activity with D-Ala [Candida] boidinii alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 95% of the activity with D-Met Rhodotorula toruloides alpha-ketoisovalerate + NH3 + H2O2 - ? 372985 1.4.3.3 D-Val + H2O + O2 - Sus scrofa 2-oxoisovalerate + NH3 + H2O2 - ? 426259 1.4.3.3 D-Val + H2O + O2 - Trigonopsis variabilis 2-oxoisovalerate + NH3 + H2O2 - ? 426259 1.4.3.3 D-Val + H2O + O2 100% activity Rubrobacter xylanophilus 2-oxoisovalerate + NH3 + H2O2 - ? 426259 1.4.3.3 D-valine + H2O + O2 - Sus scrofa alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - Neurospora crassa alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - [Candida] boidinii alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - Rhodotorula toruloides alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - Chlorella vulgaris alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - Trigonopsis variabilis alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 - Cyprinus carpio alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 best substrate Rhodotorula toruloides alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 0.35% activity compared to D-methionine Glutamicibacter protophormiae alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 60% activity compared to D-alanine Rhodotorula toruloides alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 63% activity compared to D-alanine Trigonopsis variabilis alpha-ketoisovaleric acid + NH3 + H2O2 - ? 259042 1.4.3.3 D-valine + H2O + O2 highly active Trigonopsis variabilis alpha-ketoisovalerate + NH3 + H2O2 - ? 396949 1.4.3.3 D-valine + H2O + O2 - Rasamsonia emersonii 2-oxoisovalerate + NH3 + H2O2 - ? 460985 1.4.3.3 DL-2-naphthyl-alanine + H2O + O2 - Rhodotorula toruloides L-2-naphthyl-alanine + 2-naphthylpyruvic acid + NH3 + H2O2 - ir 426338 1.4.3.3 DL-homophenylalanine + H2O + O2 31% activity compared to D-methionine Glutamicibacter protophormiae homophenylpyruvate + NH3 + H2O2 - ? 397081 1.4.3.3 DL-tert-leucine + H2O + O2 0.12% activity compared to D-methionine Glutamicibacter protophormiae ? - ? 397084 1.4.3.3 epsilon-N-benzoyl-D-lysine + H2O + O2 - Sus scrofa 6-benzylamino-2-oxohexanoate + NH3 + H2O2 - ? 259051 1.4.3.3 Gly + H2O + O2 - Homo sapiens acetate + NH3 + H2O2 - ? 373309 1.4.3.3 Gly + H2O + O2 - Sus scrofa acetate + NH3 + H2O2 - ? 373309 1.4.3.3 Gly + H2O + O2 15% of the activity with D-Ala Candida parapsilosis acetate + NH3 + H2O2 - ? 373309 1.4.3.3 Gly + H2O + O2 2% of the activity with D-Met Acrostalagmus luteoalbus acetate + NH3 + H2O2 - ? 373309 1.4.3.3 Gly + H2O + O2 3% of the activity with D-Met Rhodotorula toruloides acetate + NH3 + H2O2 - ? 373309 1.4.3.3 Gly + H2O + O2 1.1% activity compared to D-Val Rubrobacter xylanophilus acetate + NH3 + H2O2 - ? 373309 1.4.3.3 glycine + 2 H2O + O2 - Sus scrofa 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + 2 H2O + O2 - Rhodotorula toruloides 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + 2 H2O + O2 - Chlorella vulgaris 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + 2 H2O + O2 poor substrate Trigonopsis variabilis 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + 2 H2O + O2 2% activity compared to D-alanine Trigonopsis variabilis 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + 2 H2O + O2 3% activity compared to D-alanine Rhodotorula toruloides 2 formic acid + NH3 + H2O2 - ? 259058 1.4.3.3 glycine + H2O + O2 - Homo sapiens glyoxylate + NH3 + H2O2 - ? 259018 1.4.3.3 glyphosate + H2O + O2 - Bradyrhizobium japonicum ? - ? 440259 1.4.3.3 L-Ala + H2O + O2 low activity Sus scrofa pyruvate + NH3 + H2O2 - ? 441497 1.4.3.3 L-Asp + H2O + O2 low activity Sus scrofa oxaloacetate + NH3 + H2O2 - ? 405573 1.4.3.3 L-DOPA + H2O + O2 - Homo sapiens 3,4-dihydroxyphenylpyruvate + NH3 + H2O2 - ? 397577 1.4.3.3 L-Pro + H2O + O2 low activity Sus scrofa 2-oxopentanoic acid + NH3 + H2O2 - ? 441542 1.4.3.3 additional information first enzyme involved in the catabolism of D-amino acids. The inducer D-Ala acts by increasing the rate of DAAO mRNA transcription. Ammonium sulfate appears to have a negative effect on DAAO mRNA translation and on the expression of DAAO activity. The best expression of DAAO activity is obtained by growing the cells for 12 h at 30°C in the presence of glucose and D-alanine using cell pre-cultured for 10 h on glucose and L-Ala Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information no activity with D-Trp, D-Tyr, D-Cys, D-Gln, D-Lys, D-Arg, D-His and D-Asp [Candida] boidinii ? - ? 89 1.4.3.3 additional information the amount of the neutral D-amino acids are regulated, each D-amino acid is regulated in a different way Mus musculus ? - ? 89 1.4.3.3 additional information activity with D-Asp is not detectable Sus scrofa ? - ? 89 1.4.3.3 additional information best substrate is by far D-methionine followed by D-phenylalanine, D-tryptophan, D-valin, and D-alanine Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information best substrate is D-valine followed by D-tryptophan, D-phenylalanine, D-alanine, and D-cysteine Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information D-aspartate and D-glutamate are no substrates Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information D-aspartate and D-glutamate are no substrates Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information D-aspartate and D-glutamate are no substrates Sus scrofa ? - ? 89 1.4.3.3 additional information D-aspartate and D-glutamate are no substrates Homo sapiens ? - ? 89 1.4.3.3 additional information D-proline is the best substrate followed by D-methionine, D-alanine, D-norleucine, D-isoleucine, and D-phenylalanine Sus scrofa ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates [Candida] boidinii ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Rubrobacter xylanophilus ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Mycobacterium leprae ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Glutamicibacter protophormiae ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Fusarium solani ? - ? 89 1.4.3.3 additional information DAAOs can be divided into two groups regarding their substrate specificity, the first group prefers amino acids with small apolar side chains (D-Ala is the best substrate), the second group prefers D-amino acids possessing large hydrophobic side chains such as D-Trp, D-Met, D-Val, and D-Phe, usually the small amino acid Gly and the charged (acidic or basic) amino acids are poor DAAO substrates Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information nearly inactive toward D-aspartic and D-glutamic acids Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information no activity with glycine, D-serine, D-asparagine, D-aspartate, D-glutamate, D-threonine, D-tryptophan, and cephalosporin C Glutamicibacter protophormiae ? - ? 89 1.4.3.3 additional information the enzyme exhibits very low activity towards basic amino acids, and it does not oxidize those with an acidic side chain Sus scrofa ? - ? 89 1.4.3.3 additional information the wild-type DAAO is mainly active on neutral D-amino acids, while basic D-amino acids are poor substrates and the acidic ones are virtually not oxidized Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information D-amino acid oxidase is an enzyme catalyzing the strict stereospecificity the oxidative deamination of neutral and polar D-amino acids to alpha-keto acids, NH3 and hydrogen peroxide Rattus norvegicus ? - ? 89 1.4.3.3 additional information DAAO is a catabolic flavoenzyme that catalyzes the oxidative deamination of D-amino acids to the corresponding a-keto acids, hydrogen peroxide, and ammonia. DAAO is strictly specific for D-isomers of amino acids Homo sapiens ? - ? 89 1.4.3.3 additional information DAO catalyzes the oxidative degradation of most of the D-amino acids in mammals Mus musculus ? - ? 89 1.4.3.3 additional information the enzyme is involved in the conversion of cephalosporin C Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information the mechanism of the enzyme regulation is complex and multi-parametric because the same enzyme simultaneously influences the level of different D-amino acids, which can result in opposing effects, overview Homo sapiens ? - ? 89 1.4.3.3 additional information the mechanism of the enzyme regulation is complex and multi-parametric because the same enzyme simultaneously influences the level of different D-amino acids, which can result in opposing effects, overview Sus scrofa ? - ? 89 1.4.3.3 additional information the mechanism of the enzyme regulation is complex and multi-parametric because the same enzyme simultaneously influences the level of different D-amino acids, which can result in opposing effects, overview Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information the mechanism of the enzyme regulation is complex and multi-parametric because the same enzyme simultaneously influences the level of different D-amino acids, which can result in opposing effects, overview Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information D-amino acid oxidase is a flavoenzyme that catalyzes the oxidation of D-amino acids to the corresponding imino acids and hydrogen peroxide Homo sapiens ? - ? 89 1.4.3.3 additional information D-amino acid oxidase is a flavoenzyme that catalyzes the oxidation of D-amino acids to the corresponding imino acids and hydrogen peroxide Rattus norvegicus ? - ? 89 1.4.3.3 additional information DAAO is a flavoprotein that catalyzes the dehydrogenation of different D-amino acids to their imino counterparts via a reduced flavin product complex. The reduced flavin is then reoxidized by O2 to yield H2O2, whereas the imino acid spontaneously hydrolyzes to the corresponding keto acid and NH4+. DAAO is strictly stereospecific and oxidizes a variety of D-amino acids, with a preference for those having small hydrophobic side chains, followed by those bearing polar, aromatic, and basic groups Sus scrofa ? - ? 89 1.4.3.3 additional information hDAAO exhibits optimal activity toward neutral D-amino acids and marginal activity toward basic ones, while acidic D-amino acids are not oxidized, structure-function relationship analysis, overview Homo sapiens ? - ? 89 1.4.3.3 additional information recombinant maltose-binding protein-fusion DAAO can oxidize D-alanine and D-aspartate, but not D-leucine, D-isoleucine, and D-serine Zea mays ? - ? 89 1.4.3.3 additional information the enzyme catalyzes oxidative deamination of D-amino acids yielding hydrogen peroxide and an imino acid. The latter is further non-enzymatically hydrolyzed to an alpha-keto acid and ammonium. DAAO is highly specific towards D-isomers of amino acids, it is almost inactive towards the corresponding L-isomer Homo sapiens ? - ? 89 1.4.3.3 additional information the enzyme catalyzes oxidative deamination of D-amino acids yielding hydrogen peroxide and an imino acid. The latter is further non-enzymatically hydrolyzed to an alpha-keto acid and ammonium. DAAO is highly specific towards D-isomers of amino acids, it is almost inactive towards the corresponding L-isomer Sus scrofa ? - ? 89 1.4.3.3 additional information the enzyme catalyzes oxidative deamination of D-amino acids yielding hydrogen peroxide and an imino acid. The latter is further non-enzymatically hydrolyzed to an alpha-keto acid and ammonium. DAAO is highly specific towards D-isomers of amino acids, it is almost inactive towards the corresponding L-isomer Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information the enzyme catalyzes oxidative deamination of D-amino acids yielding hydrogen peroxide and an imino acid. The latter is further non-enzymatically hydrolyzed to an alpha-keto acid and ammonium. DAAO is highly specific towards D-isomers of amino acids, it is almost inactive towards the corresponding L-isomer. The wild-type enzyme is inactive towards D-Asp, being however very active with D-Ala Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information DAAO interacts with its physiological partner pLG72, the interaction is not inhibited by benzoate and chlorpromazine Homo sapiens ? - ? 89 1.4.3.3 additional information the flavoenzyme catalyzes the oxidative deamination of neutral and basic D-amino acids to the corresponding 2-oxo acids and H2O2 with concomitant reduction of FAD Rattus norvegicus ? - ? 89 1.4.3.3 additional information comparison of the kinetics of trypsin cleavage of hDAAO in the presence of various ligands, overview Homo sapiens ? - ? 89 1.4.3.3 additional information conversion of cephalosporine C to 7-aminocephalosporanic acid and spontaneous decarboxylation of oxoadipyl-7-amino cephalosporanic acid is promoted by the H2O2 formed in the oxidase reaction of TvDAO Trigonopsis variabilis ? - ? 89 1.4.3.3 additional information DAO shows no activity with D-Asp, N-methyl-D-Asp, and D-Glu Caenorhabditis elegans ? - ? 89 1.4.3.3 additional information specific dynamic channel for the diffusion of O2 leads from solvent to the flavin Si-side. O2 affinity, catalytic center, and substrate binding of wild-type and mutant enzymes, molecular dynamics simulations built from the three-dimensional structure, PDB ID 1c0p, in which the ligand D-Ala is replaced by imino pyruvate, overview Rhodotorula toruloides ? - ? 89 1.4.3.3 additional information the enzyme interacts with the mammalian protein modulator pLG72 Rattus norvegicus ? - ? 89 1.4.3.3 additional information D-aspartate and glycine are no substrates Rattus norvegicus ? - ? 89 1.4.3.3 additional information D-allo-isoleucine, D-valine, O-methyl-DL-serine, D-alanine, and D-proline are no substrates uncultured bacterium ? - ? 89 1.4.3.3 additional information no activity with D-Pro, D-Cys, D-Asp, L-Val, L-Leu, and L-Ile Rubrobacter xylanophilus ? - ? 89 1.4.3.3 additional information DAAO is mainly active on neutral, hydrophobic and slightly polar D-amino acids and shows a preference for aromatic amino acids Homo sapiens ? - - 89 1.4.3.3 additional information no substrates: L-isoleucine, L-valine, L-methionine Rasamsonia emersonii ? - - 89 1.4.3.3 N-acetyl-D-alanine + H2O + O2 - Homo sapiens pyruvate + aminoacetate + H2O2 - ? 397851 1.4.3.3 N-methyl-D-aspartate + H2O + O2 - Homo sapiens oxaloacetate + methylamine + H2O2 - ? 260689 1.4.3.3 N-methyl-D-aspartate + H2O + O2 wild-type enzyme shows no activity, mutant enzyme M213R is active Rhodotorula toruloides ? - ? 373936 1.4.3.3 N-methyl-DL-Leu + H2O + O2 5.8% activity compared to D-Met uncultured bacterium 4-methyl-2-oxopentanoate + methylamine + H2O2 - ? 441678 1.4.3.3 N-methyl-DL-leucine + H2O + O2 2.1% activity compared to D-methionine Glutamicibacter protophormiae ? - ? 397898 1.4.3.3 O-methyl-DL-serine + H2O + O2 0.33% activity compared to D-methionine Glutamicibacter protophormiae ? - ? 397997 1.4.3.3 phenylglycine + H2O + O2 - Sus scrofa benzoylformic acid + NH3 + H2O2 - ? 259067 1.4.3.3 phenylglycine + H2O + O2 - Rhodotorula toruloides benzoylformic acid + NH3 + H2O2 - ? 259067 1.4.3.3 phenylglycine + H2O + O2 - Trigonopsis variabilis benzoylformic acid + NH3 + H2O2 - ? 259067 1.4.3.3 thiazolidine-2-carboxylic acid + H2O + O2 - Sus scrofa ? + NH3 + H2O2 - ? 259056 1.4.3.3 thiazolidine-2-carboxylic acid + H2O + O2 - Rhodotorula toruloides ? + NH3 + H2O2 - ? 259056 1.4.3.3 tryptophan + H2O + O2 - Homo sapiens indol-3-pyruvic acid + NH3 + H2O2 - ? 461384