1.2.1.80 a long-chain aldehyde + an [acyl-carrier protein] + NAD(P)+ - Synechococcus elongatus a long-chain acyl-[acyl-carrier protein] + NAD(P)H + H+ - ? 460125 1.2.1.80 fatty acyl-CoA + NAD(P)H + H+ CpFAS1-R can only utilize very long chain fatty acyl-CoAs as substrates, with activity on C26 > C24 > C22 > C20, but no activity on C18 and C16 or fewer carbons Cryptosporidium parvum fatty aldehyde + CoA + NAD(P)+ since aldehydes are toxic to cells it is very likely that the fatty aldehyde is immediately transformed into the corresponding alcohol by the enzyme complex ? 426397 1.2.1.80 fatty acyl-[acyl carrier protein] + NAD(P)H + H+ kinetically preferred and likely the in vivo substrate Synechococcus elongatus fatty aldehyde + acyl carrier protein + NAD(P)+ - ? 413382 1.2.1.80 fatty acyl-[acyl carrier protein] + NAD(P)H + H+ kinetically preferred and likely the in vivo substrate Synechococcus elongatus PCC 7942 fatty aldehyde + acyl carrier protein + NAD(P)+ - ? 413382 1.2.1.80 fatty acyl-[acyl-carrier protein] + NAD(P)H + H+ - Cryptosporidium parvum fatty aldehyde + acyl-carrier protein + NAD(P)+ - ? 424807 1.2.1.80 hexacosanoyl-CoA + NAD(P)H + H+ - Cryptosporidium parvum hexacosanal + CoA + NAD(P)+ - ? 426478 1.2.1.80 hexadecanoyl-[acyl-carrier protein] + NAD(P)H + H+ substrate selectivity Synechococcus sp. hexadecanal + acyl-carrier protein + NAD(P)+ - ? 417960 1.2.1.80 hexadecanoyl-[acyl-carrier protein] + NAD(P)H + H+ acyl-ACP is kinetically preferred and is likely the in vivo substrate Synechococcus sp. hexadecanal + acyl-carrier protein + NAD(P)+ - ? 417960 1.2.1.80 hexadecanoyl-[acyl-carrier protein] + NAD(P)H + H+ acyl-CoA and acyl-ACP can serve as substrates Arabidopsis thaliana hexadecanal + acyl-carrier protein + NAD(P)+ hexadecanal is a reaction intermediate that is further converted into hexadecanol ? 417960 1.2.1.80 hexadecanoyl-[acyl-carrier protein] + NAD(P)H + H+ substrate selectivity Synechococcus sp. PCC 7942 hexadecanal + acyl-carrier protein + NAD(P)+ - ? 417960 1.2.1.80 hexadecanoyl-[acyl-carrier protein] + NAD(P)H + H+ acyl-ACP is kinetically preferred and is likely the in vivo substrate Synechococcus sp. PCC 7942 hexadecanal + acyl-carrier protein + NAD(P)+ - ? 417960 1.2.1.80 additional information does not reduce acyl-CoA Synechococcus elongatus ? - ? 89 1.2.1.80 additional information because of technical difficulties in preparing the native substrates for CpFAS1-R, which are very long chain fatty acyl-ACPs, long chain and very long chain fatty acyl-CoAs are used as substrates to assay CpFAS1-R activity Cryptosporidium parvum ? - ? 89 1.2.1.80 additional information in Saccharomyces cerevisiae overexpressed truncated version of AtFAR6, which lacks the N-terminal extension, produces C16:0 primary fatty alcohol as well as C18:0 fatty alcohols much more efficiently than the full length protein Arabidopsis thaliana ? - ? 89 1.2.1.80 additional information does not reduce acyl-CoA Synechococcus elongatus PCC 7942 ? - ? 89 1.2.1.80 oleoyl-[acyl carrier protein] + NAD(P)H + H+ - Synechococcus elongatus oleic aldehyde + acyl carrier protein + NAD(P)+ - ? 415077 1.2.1.80 oleoyl-[acyl carrier protein] + NAD(P)H + H+ - Synechococcus elongatus PCC 7942 oleic aldehyde + acyl carrier protein + NAD(P)+ - ? 415077 1.2.1.80 oleoyl-[acyl carrier protein] + NADPH + H+ - Synechocystis sp. PCC 6803 oleic aldehyde + acyl carrier protein + NADP+ - ? 460225 1.2.1.80 palmitoyl-CoA + NADPH + H+ - Synechococcus elongatus hexadecanal + CoA + NADP+ - ? 426897 1.2.1.80 palmitoyl-CoA + NADPH + H+ - Synechococcus elongatus PCC 7942 hexadecanal + CoA + NADP+ - ? 426897 1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+ - Synechocystis sp. PCC 6803 hexadecanal + acyl carrier protein + NADP+ - ? 460227 1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+ specific substrate Oryza sativa hexadecanal + acyl carrier protein + NADP+ - ? 460227 1.2.1.80 stearoyl-CoA + NADPH + H+ - Synechococcus elongatus octadecanal + CoA + NADP+ - ? 427066 1.2.1.80 stearoyl-CoA + NADPH + H+ - Synechococcus elongatus PCC 7942 octadecanal + CoA + NADP+ - ? 427066 1.2.1.80 stearoyl-[acyl carrier protein] + NADPH + H+ - Synechocystis sp. PCC 6803 stearoylaldehyde + acyl carrier protein + NADP+ - ? 460244 1.2.1.80 stearoyl-[acyl-carrier protein] + NAD(P)H + H+ - Nostoc punctiforme stearylaldehyde + an [acyl-carrier protein] + NAD(P)+ the enzyme specifically transfers the pro-R hydride of NADPH to the Cys294-thioester intermediate to afford its aldehyde product ? 439913 1.2.1.80 stearoyl-[acyl-carrier protein] + NAD(P)H + H+ - Nostoc punctiforme ATCC 29133 stearylaldehyde + an [acyl-carrier protein] + NAD(P)+ the enzyme specifically transfers the pro-R hydride of NADPH to the Cys294-thioester intermediate to afford its aldehyde product ? 439913