1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Agrobacterium aurantiacum 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O 4-ketozeaxanthin is adonixanthin ? 416206 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - marine bacterium P99-3 adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Paracoccus sp. adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma VKPM Y2410 adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3'-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. SD212 adonixanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416207 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - marine bacterium P99-3 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Paracoccus sp. 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Agrobacterium aurantiacum 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O 4-ketozeaxanthin is adonixanthin ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma VKPM Y2410 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 3-hydroxyechinenone + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. SD212 4-ketozeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416233 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 - Alcaligenes sp. astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 - Pantoea ananatis astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 - Agrobacterium aurantiacum astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 adonirubin is also named phoenicoxanthin or (3S)-3-hydroxy-beta,beta-carotene-4,4'-dione marine bacterium P99-3 astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 adonirubin is also named phoenicoxanthin or (3S)-3-hydroxy-beta,beta-carotene-4,4'-dione Brevundimonas sp. astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 adonirubin is also named phoenicoxanthin or (3S)-3-hydroxy-beta,beta-carotene-4,4'-dione Paracoccus sp. astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 adonirubin is also named phoenicoxanthin or (3S)-3-hydroxy-beta,beta-carotene-4,4'-dione Pantoea ananatis astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 adonirubin + reduced acceptor + H+ + O2 adonirubin is also named phoenicoxanthin or (3S)-3-hydroxy-beta,beta-carotene-4,4'-dione Brevundimonas sp. SD212 astaxanthin + acceptor + H2O - ? 416509 1.14.15.24 alpha-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Arabidopsis thaliana zeinoxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416546 1.14.15.24 alpha-carotene + reduced acceptor + H+ + O2 - Arabidopsis thaliana zeinoxanthin + acceptor + H2O - ? 416548 1.14.15.24 alpha-carotene + reduced acceptor + H+ + O2 - Oryza sativa zeinoxanthin + acceptor + H2O - ? 416548 1.14.15.24 alpha-carotene + reduced acceptor + H+ + O2 - Arabidopsis thaliana lutein + acceptor + H2O - ? 427346 1.14.15.24 beta-carotene + 2 NADH + H+ + O2 overall reaction Adonis aestivalis zeaxanthin + 2 NAD+ + 2 H2O - ? 416700 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Arabidopsis thaliana beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea agglomerans beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Oryza sativa beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - marine bacterium P99-3 beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Adonis aestivalis beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Paracoccus sp. beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Ipomoea batatas beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O beta-cryptoxanthin is 3-hydroxy-beta,beta-carotene ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the BCH1 and BCH2 enzymes primarily catalyze the two beta-ring hydroxylations of beta-carotene Arabidopsis thaliana beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the hydroxylase activity is strictly dependent upon the presence of NADPH, ferredoxin, ferredoxin oxidoreductase, and catalase Capsicum annuum beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 upon in vitro reconstitution of CYP175A1 activity with purified recombinant flavodoxin and flavodoxin reductase from Escherichia coli, only very low beta-cryptoxanthin production is observed Thermus thermophilus beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma VKPM Y2410 beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O beta-cryptoxanthin is 3-hydroxy-beta,beta-carotene ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 upon in vitro reconstitution of CYP175A1 activity with purified recombinant flavodoxin and flavodoxin reductase from Escherichia coli, only very low beta-cryptoxanthin production is observed Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. SD212 beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416702 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Arabidopsis thaliana cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416703 1.14.15.24 beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the enzyme prefers alpha-carotene over beta-carotene as a substrate Oryza sativa zeinoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 427406 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Arabidopsis thaliana zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Pantoea agglomerans zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Haematococcus lacustris zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Gentiana lutea zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Agrobacterium aurantiacum zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Pantoea ananatis zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Phaffia rhodozyma zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O zeaxanthin is 3,3'-dihydroxy-beta,beta-carotene ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction marine bacterium P99-3 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Brevundimonas sp. zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Paracoccus sp. zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Pantoea ananatis zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Thermus thermophilus zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O zeaxanthin is beta,beta-carotene-3,3'-diol ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Arabidopsis thaliana zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O zeaxanthin is beta,beta-carotene-3,3'-diol ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 beta-carotene is only partly converted into zeaxanthin by Chx, though a major portion (75-80%) is left Pantoea ananatis zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzyme catalyzes the hydroxylation of beta-carotene at 3- and 3'-positions Thermus thermophilus zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzymes possess greater ability to convert beta-carotene to zeaxanthin than canthaxanthin to astaxanthin Pantoea ananatis zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzymes possess smaller ability to convert beta-carotene to zeaxanthin than canthaxanthin to astaxanthin Agrobacterium aurantiacum zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 the hydroxylase activity is strictly dependent upon the presence of NADPH, ferredoxin, ferredoxin oxidoreductase, and catalase Capsicum annuum zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 the enzyme from the yeast Xanthophyllomyces dendrorhous is bifunctional and also catalyses the activity of beta-carotene 4-ketolase Phaffia rhodozyma zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 the enzyme plays an important role in astaxanthin production Pantoea ananatis zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Phaffia rhodozyma VKPM Y2410 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O zeaxanthin is 3,3'-dihydroxy-beta,beta-carotene ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O zeaxanthin is beta,beta-carotene-3,3'-diol ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzyme catalyzes the hydroxylation of beta-carotene at 3- and 3'-positions Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 the enzyme from the yeast Xanthophyllomyces dendrorhous is bifunctional and also catalyses the activity of beta-carotene 4-ketolase Phaffia rhodozyma ATCC 96815 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction Brevundimonas sp. SD212 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Haematococcus lacustris Flotow NIES-144 zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 415605 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Oryza sativa zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 427405 1.14.15.24 beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 LUT1/CYP97C1 protein reveals a major beta-carotene hydroxylase activity in vivo when depleted in its preferred substrate alpha-carotene Arabidopsis thaliana zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 427405 1.14.15.24 beta-carotene + NADPH + H+ + O2 overall reaction, the enzymes possess smaller ability to convert beta-carotene to zeaxanthin than canthaxanthin to astaxanthin Alcaligenes sp. zeaxanthin + NADP+ + H2O - ? 416705 1.14.15.24 beta-carotene + reduced acceptor + o2 - Phaffia rhodozyma astaxanthin + acceptor + H2O - ? 450898 1.14.15.24 beta-carotene + reduced acceptor + o2 - Phaffia rhodozyma ATCC 96594 astaxanthin + acceptor + H2O - ? 450898 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the enzyme can convert not only the (un-substituted) beta ring but also the 4-ketolated beta-ring into the respective 3-hydroxylated groups Paracoccus sp. ? - ? 427404 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the enzyme can convert not only the (un-substituted) beta ring but also the 4-ketolated beta-ring into the respective 3-hydroxylated groups Brevundimonas sp. ? - ? 427404 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the enzyme can convert not only the (un-substituted) beta ring but also the 4-ketolated beta-ring into the respective 3-hydroxylated groups Brevundimonas sp. SD212 ? - ? 427404 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Alcaligenes sp. beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Fulvimarina pelagi beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Agrobacterium aurantiacum beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Capsicum annuum beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Lycium barbarum beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Alcaligenes sp. PC-1 beta-cryptoxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442333 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Chlamydomonas reinhardtii zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Zea mays zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Arabidopsis thaliana zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Haematococcus lacustris zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Ipomoea batatas zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Lycium barbarum zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Chromochloris zofingiensis zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 overall reaction Zea mays zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 overall reaction Fulvimarina pelagi zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 overall reaction Capsicum annuum zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 overall reaction Lycium barbarum zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 overall reaction Alcaligenes sp. PC-1 zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442334 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Arabidopsis thaliana zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Alcaligenes sp. zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Phaffia rhodozyma zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Oryza sativa zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Agrobacterium aurantiacum zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - marine bacterium P99-3 zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Adonis aestivalis zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Paracoccus sp. zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Ipomoea batatas zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 the hydroxylase activity is strictly dependent upon the presence of NADPH, ferredoxin, ferredoxin oxidoreductase, and catalase Capsicum annuum zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416709 1.14.15.24 beta-cryptoxanthin + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Fulvimarina pelagi zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442335 1.14.15.24 beta-cryptoxanthin + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Capsicum annuum zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442335 1.14.15.24 beta-cryptoxanthin + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Lycium barbarum zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442335 1.14.15.24 beta-cryptoxanthin + reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Alcaligenes sp. PC-1 zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 442335 1.14.15.24 beta-zeacarotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 beta-zeacarotene is 7',8'-dihydro-beta,psi-carotene Arabidopsis thaliana hydroxy-beta-zeacarotene + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O hydroxy-beta-zeacarotene is 7',8'-dihydro-beta,psi-carotene-3-ol ? 416725 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Alcaligenes sp. adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Pantoea ananatis adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Agrobacterium aurantiacum adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - marine bacterium P99-3 adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Brevundimonas sp. adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Paracoccus sp. adonirubin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416742 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Haematococcus lacustris phoenicoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416744 1.14.15.24 canthaxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 canthaxanthin is beta,beta-carotene-4-4'-dione Phaffia rhodozyma phoenicoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416744 1.14.15.24 canthaxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Haematococcus lacustris astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O astaxanthin is also named adonirubin ? 416743 1.14.15.24 canthaxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzymes possess greater ability to convert canthaxanthin to astaxanthin than beta-carotene to zeaxanthin Alcaligenes sp. astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416743 1.14.15.24 canthaxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzymes possess greater ability to convert canthaxanthin to astaxanthin than beta-carotene to zeaxanthin Agrobacterium aurantiacum astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416743 1.14.15.24 canthaxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 overall reaction, the enzymes possess smaller ability to convert canthaxanthin to astaxanthin than beta-carotene to zeaxanthin Pantoea ananatis astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416743 1.14.15.24 canthaxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Haematococcus lacustris Flotow NIES-144 astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O astaxanthin is also named adonirubin ? 416743 1.14.15.24 cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Arabidopsis thaliana zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416799 1.14.15.24 echinenone + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus 3'-hydroxyechinenone + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416968 1.14.15.24 echinenone + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 3'-hydroxyechinenone + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416968 1.14.15.24 echinenone + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 echinenone is beta,beta-carotene-4-one Phaffia rhodozyma 3-hydroxyechinenone + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 416969 1.14.15.24 echinenone + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - marine bacterium P99-3 3'-hydroxyechinenone + 3-hydroxyechinenone + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416967 1.14.15.24 echinenone + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Brevundimonas sp. 3'-hydroxyechinenone + 3-hydroxyechinenone + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416967 1.14.15.24 echinenone + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Paracoccus sp. 3'-hydroxyechinenone + 3-hydroxyechinenone + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416967 1.14.15.24 echinenone + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Pantoea ananatis 3'-hydroxyechinenone + 3-hydroxyechinenone + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416967 1.14.15.24 echinenone + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 conversion occurs via 3- and 3'-hydroxyechinenone Agrobacterium aurantiacum 4-ketozeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 416970 1.14.15.24 additional information although beta-hydroxylase 1 is active toward beta-rings, it can also add a hydroxyl group to epsilon-rings in vitro, although at much lower efficiency Arabidopsis thaliana ? - ? 89 1.14.15.24 additional information although beta-hydroxylase 2 is most active toward beta-rings, it can also add a hydroxyl group to epsilon-rings in vitro, although at much lower efficiency Arabidopsis thaliana ? - ? 89 1.14.15.24 additional information the beta-hydroxylase is weakly (6%) active towards epsilon-rings in comparison to beta-rings Arabidopsis thaliana ? - ? 89 1.14.15.24 additional information the epsilon rings of delta-carotene (epsilon,psi-carotene) and alpha-zeacarotene(7',8'-dihydro-epsilon,psi-carotene) are poor substrates for the enzyme Arabidopsis thaliana ? - ? 89 1.14.15.24 phoenicoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 - Haematococcus lacustris astaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O - ? 444388 1.14.15.24 phoenicoxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 - Phaffia rhodozyma astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O astaxanthin is 3,3'-dihydroxy-beta,beta-carotene-4-4'-dione ? 417476 1.14.15.24 phoenicoxanthin + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 phoenicoxanthin is adonirubin Agrobacterium aurantiacum astaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O - ? 417476