1.13.11.68 (7E,7'E,9Z,9'E)-7',8'-dihydro-psi,psi-carotene + O2 - Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone - ? 442996 1.13.11.68 (7E,7'E,9Z,9'E)-lycopene + O2 - Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone - ? 442995 1.13.11.68 9'-cis-cryptoxanthin + O2 - Arabidopsis thaliana ? - ? 442993 1.13.11.68 9'-cis-neurosporene + O2 low activity Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone - ? 442994 1.13.11.68 9'-cis-neurosporene + O2 - Arabidopsis thaliana 9'-cis-apo-10'-neurosporenal + ? - ? 462181 1.13.11.68 9-cis-beta-carotene + 02 - Pisum sativum 9-cis-beta-apo-10'-carotenal + beta-ionone - ? 428122 1.13.11.68 9-cis-beta-carotene + 02 - Arabidopsis thaliana 9-cis-beta-apo-10'-carotenal + beta-ionone - ? 428122 1.13.11.68 9-cis-beta-carotene + 02 - Oryza sativa 9-cis-beta-apo-10'-carotenal + beta-ionone - ? 428122 1.13.11.68 9-cis-beta-carotene + O2 - Pisum sativum 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Arabidopsis thaliana 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Cicer arietinum 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Oryza sativa 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Petunia x hybrida 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Chimonanthus praecox 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 - Crocus sativus 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-beta-carotene + O2 AtCCD7 preferentially cleaves 9-cis-beta-carotene Arabidopsis thaliana 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 442234 1.13.11.68 9-cis-cryptoxanthin + O2 - Arabidopsis thaliana ? - ? 442998 1.13.11.68 9-cis-lutein + O2 - Pisum sativum 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + 3-hydroxy-beta-ionone - ? 442999 1.13.11.68 9-cis-lutein + O2 - Arabidopsis thaliana 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + 3-hydroxy-beta-ionone - ? 442999 1.13.11.68 9-cis-lutein + O2 - Pisum sativum 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + ? - ? 462184 1.13.11.68 9-cis-lutein + O2 - Arabidopsis thaliana 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + ? - ? 462184 1.13.11.68 9-cis-lutein + O2 - Oryza sativa 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + ? - ? 462184 1.13.11.68 9-cis-lutein + O2 - Petunia x hybrida 9-cis-3-hydroxy-epsilon-apo-10'-carotenal + ? - ? 462184 1.13.11.68 9-cis-lycopene + O2 - Arabidopsis thaliana 9-cis-apo-10'-lycopenal + ? - ? 462185 1.13.11.68 9-cis-zeaxanthin + O2 - Pisum sativum 9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone - ? 442235 1.13.11.68 9-cis-zeaxanthin + O2 - Arabidopsis thaliana 9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone - ? 442235 1.13.11.68 9-cis-zeaxanthin + O2 - Pisum sativum 9-cis-3-hydroxy-beta-apo-10'-carotenal + ? - ? 462186 1.13.11.68 9-cis-zeaxanthin + O2 - Arabidopsis thaliana 9-cis-3-hydroxy-beta-apo-10'-carotenal + ? - ? 462186 1.13.11.68 9-cis-zeaxanthin + O2 - Oryza sativa 9-cis-3-hydroxy-beta-apo-10'-carotenal + ? - ? 462186 1.13.11.68 9-cis-zeaxanthin + O2 - Petunia x hybrida 9-cis-3-hydroxy-beta-apo-10'-carotenal + ? - ? 462186 1.13.11.68 9-cis-zeta-carotene + O2 - Arabidopsis thaliana 9-cis-zeta-apo-10'-carotenal + beta-ionone - ? 443000 1.13.11.68 9-cis-zeta-carotene + O2 - Arabidopsis thaliana 9-cis-zeta-apo-10'-carotenal + ? - ? 462188 1.13.11.68 beta-carotene + O2 - Arabidopsis thaliana 10'-apo-beta-carotenal + beta-ionone - ? 420385 1.13.11.68 beta-carotene + O2 - Vitis vinifera 7-cis-8'-apo-beta-carotenal + beta-cyclocitral - ? 462300 1.13.11.68 beta-carotene + O2 isoform CCD1 prefers to cleave the 9, 10 position of beta-carotene Vitis vinifera 9-cis-10'-apo-beta-carotenal + beta-ionone - ? 462301 1.13.11.68 additional information no substrate: lycopene, lutein, zeaxanthin, violaxanthin, or neoxanthin Arabidopsis thaliana ? - ? 89 1.13.11.68 additional information recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin Zea mays ? - ? 89 1.13.11.68 additional information recombinant ZpCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin Zea mays subsp. parviglumis ? - ? 89 1.13.11.68 additional information substrate- and stereospecificity of Arabidopsis thaliana carotenoid cleavage dioxygenase 7, overview Arabidopsis thaliana ? - ? 89 1.13.11.68 additional information substrate- and stereospecificity of Pisum sativum carotenoid cleavage dioxygenase 7, overview Pisum sativum ? - ? 89 1.13.11.68 additional information AtCCD7 cleaves asymmetrically at the 9, 10, and 9', 10' bonds Arabidopsis thaliana ? - ? 89 1.13.11.68 additional information enzyme CCD7 cleaves different 9-cis-carotenoids, yielding hydroxylated 9-cis-apo-10'-carotenals that may lead to hydroxylated carlactones, but show highest affinity for 9-cis-beta-carotene. The enzyme has a higher affinity to 9-cis-beta-carotene than to 9-cis-zeaxanthin, but converts the latter with higher rate. No detectable conversion of 9-cis-violaxanthin, all-trans-lutein, -zeaxanthin or -cryptoxanthin Pisum sativum ? - ? 89 1.13.11.68 additional information enzyme CCD7 cleaves different 9-cis-carotenoids, yielding hydroxylated 9-cis-apo-10'-carotenals that may lead to hydroxylated carlactones, but show highest affinity for 9-cis-beta-carotene. The enzyme has a higher affinity to 9-cis-beta-carotene than to 9-cis-zeaxanthin, but converts the latter with higher rate. No detectable conversion of 9-cis-violaxanthin, all-trans-lutein, -zeaxanthin or -cryptoxanthin Arabidopsis thaliana ? - ? 89 1.13.11.68 additional information enzyme substrate specificity, dynamic modeling, overview. No activity with the tri-cis-configured PDS or ZDS intermediates and products, i.e. 9,15-di-cis-phytofluene, 9,15,9'-tri-cis-zeta-carotene, 7,9,9'-tri-cis-neurosporene, and 7,9,9',7-tetra-cis-lycopene, as well as with non-canonical isomers of phytofluene (9-cis, 15-cis, all-trans). 9-cis-Lycopene is a poor substrate, and all-trans-lycopene is no substrate. AtCCD7 shows specificity for cleavage of the trans-configured C9-C10 double bond Arabidopsis thaliana ? - ? 89 1.13.11.68 additional information the enzyme does not act on 9-cis-violaxanthin Arabidopsis thaliana ? - - 89 1.13.11.68 additional information recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin Zea mays B73 ? - ? 89