1.1.1.245 1,2-cycloheptanediol + NAD+ relative oxidation activity at 25% the rate of cyclohexanol oxidation Pseudomonas sp. cycloheptane-1,2-dione + NADH - ? 187923 1.1.1.245 1-butanol + NAD+ poor substrate Nocardia sp. butanal + NADH - ? 187940 1.1.1.245 1-butanol + NAD+ relative activity at 20% the rate of cyclohexanol oxidation Rhodococcus sp. butanal + NADH - ? 187940 1.1.1.245 1-decanol + NAD+ poor substrate Nocardia sp. dodecanal + NADH - ? 187947 1.1.1.245 1-dodecanol + NAD+ poor substrate Nocardia sp. dodecanal + NADH - ? 187942 1.1.1.245 1-heptanol + NAD+ poor substrate Nocardia sp. heptanal + NADH - ? 187925 1.1.1.245 1-heptanol + NAD+ relative oxidation activity at 32% the rate of cyclohexanol oxidation Pseudomonas sp. heptanal + NADH - ? 187925 1.1.1.245 1-hexanol + NAD+ relative oxidation activity at 21% the rate of cyclohexanol oxidation Rhodococcus sp. hexanal + NADH - ? 187924 1.1.1.245 1-hexanol + NAD+ relative oxidation activity at 7% the rate of cyclohexanol oxidation Pseudomonas sp. hexanal + NADH - ? 187924 1.1.1.245 1-octanol + NAD+ poor substrate Nocardia sp. octanal + NADH - ? 187939 1.1.1.245 1-pentanol + NAD+ relative activity at 23% the rate of cyclohexanol oxidation Rhodococcus sp. n-pentanal + NADH - ? 187954 1.1.1.245 1-propanol + NAD+ - Saccharolobus solfataricus propionaldehyde + NADH - ? 187952 1.1.1.245 1-propanol + NAD+ relative activity at 20% the rate of cyclohexanol oxidation Rhodococcus sp. propionaldehyde + NADH - ? 187952 1.1.1.245 2,3-butanediol + NAD+ relative activity at 4% the rate of cyclohexanol oxidation Nocardia sp. ? + NADH - ? 187941 1.1.1.245 2,3-dimethylcyclohexanol + NAD+ relative activity at 78% the rate of cyclohexanol oxidation Nocardia sp. 2,3-dimethylcyclohexanone + NADH - ? 187933 1.1.1.245 2,6-dimethylcyclohexanol + NAD+ relative activity at 14% the rate of cyclohexanol oxidation Nocardia sp. 2,6-dimethylcyclohexanone + NADH - ? 187934 1.1.1.245 2-butanol + NAD+ relative activity at 44% the rate of cyclohexanol oxidation Rhodococcus sp. 2-butanone + NADH - ? 187957 1.1.1.245 2-cyclohexanol + NAD+ relative oxidation activity at 142% the rate of cyclohexanol oxidation Pseudomonas sp. 2-cyclohexenone + NADH slow reduction r 187922 1.1.1.245 2-hydroxycyclohexanone + NADH relative activity at 50% the rate of cyclohexanone reduction Pseudomonas sp. ? + NAD+ - ? 187928 1.1.1.245 2-methyl-1-butanol + NAD+ relative activity at 26% the rate of cyclohexanol oxidation Rhodococcus sp. 2-methyl-1-butanal + NADH - ? 187956 1.1.1.245 2-methyl-1-pentanol + NAD+ poor substrate Nocardia sp. 2-methylpentanal + NADH - ? 187944 1.1.1.245 2-methyl-1-propanol + NAD+ relative activity at 17% the rate of cyclohexanol oxidation Rhodococcus sp. isobutyraldehyde + NADH - ? 187955 1.1.1.245 2-methyl-2-propanol + NAD+ relative activity at 16% the rate of cyclohexanol oxidation Rhodococcus sp. ? + NADH - ? 187958 1.1.1.245 2-methylcyclohexanol + NAD+ relative activity at 51% the rate of cyclohexanol oxidation Nocardia sp. 2-methylcyclohexanone + NADH - ? 187904 1.1.1.245 2-pentanol + NAD+ relative activity at 43% the rate of cyclohexanol oxidation Nocardia sp. 2-pentanone + NADH - ? 187936 1.1.1.245 2-propanol + NAD+ relative activity at 17% the rate of cyclohexanol oxidation Rhodococcus sp. acetone + NADH - ? 187935 1.1.1.245 2-propanol + NAD+ relative activity at 19% the rate of cyclohexanol oxidation Nocardia sp. acetone + NADH - ? 187935 1.1.1.245 3-cyclohexyl-1-propanol + NAD+ poor substrate Nocardia sp. 3-cyclohexyl-1-propanal + NADH - ? 187943 1.1.1.245 3-hexanol + NAD+ relative activity at 196% the rate of cyclohexanol oxidation Nocardia sp. 3-hexanone + NADH - ? 187937 1.1.1.245 3-methylcyclohexanol + NAD+ relative activity at 74% the rate of cyclohexanol oxidation Nocardia sp. 3-methylcyclohexanone + NADH - ? 186880 1.1.1.245 4-heptanol + NAD+ relative activity at 125% the rate of cyclohexanol oxidation Nocardia sp. 4-heptanone + NADH - ? 187938 1.1.1.245 4-methyl-1-pentanol + NAD+ poor substrate Nocardia sp. 4-methylpentanal + NADH - ? 187945 1.1.1.245 4-methylcyclohexanol + NAD+ relative activity at 66% the rate of cyclohexanol oxidation Nocardia sp. 4-methylcyclohexanone + NADH - ? 187906 1.1.1.245 benzyl alcohol + NAD+ poor substrate Nocardia sp. benzaldehyde + NADH - ? 186879 1.1.1.245 benzyl alcohol + NAD+ - Saccharolobus solfataricus benzylaldehyde + NADH - ? 384273 1.1.1.245 cis-cyclopentane-1,2-diol + NAD+ relative activity at 27% the rate of cyclohexanol oxidation Rhodococcus sp. ? + NADH - ? 187948 1.1.1.245 cycloheptanone + NADH relative activity at 10% the rate of cyclohexanone reduction Pseudomonas sp. cycloheptanol + NAD+ - ? 187927 1.1.1.245 cyclohexan-1,2-diol + NAD+ - Xanthobacter sp. cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity at 43% the rate of cyclohexanol oxidation Nocardia sp. cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity of cis-isomer at 28% the rate of cyclohexanol oxidation Rhodococcus sp. cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity of cis/trans mixture at 123% the rate of cyclohexanol oxidation Rhodococcus sp. cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity of trans-isomer at 146% the rate of cyclohexanol oxidation Rhodococcus sp. cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity at 15% the rate of cyclohexanol oxidation Pseudomonas sp. cyclohexane-1,2-dione + NADH slow reduction r 187919 1.1.1.245 cyclohexan-1,2-diol + NAD+ relative oxidation activity of cis-isomer at 28% the rate of cyclohexanol oxidation Rhodococcus sp. TK6 cyclohexane-1,2-dione + NADH - ? 187919 1.1.1.245 cyclohexane-1,3-diol + NAD+ - Xanthobacter sp. cyclohexane-1,3-dione + NADH - ? 187920 1.1.1.245 cyclohexane-1,3-diol + NAD+ relative oxidation activity at 96% the rate of cyclohexanol oxidation Nocardia sp. cyclohexane-1,3-dione + NADH - ? 187920 1.1.1.245 cyclohexane-1,3-diol + NAD+ relative oxidation activity at 28% the rate of cyclohexanol oxidation Rhodococcus sp. cyclohexane-1,3-dione + NADH - ? 187920 1.1.1.245 cyclohexane-1,3-diol + NAD+ relative oxidation activity at 14% the rate of cyclohexanol oxidation Pseudomonas sp. cyclohexane-1,3-dione + NADH slow reduction r 187920 1.1.1.245 cyclohexane-1,4-diol + NAD+ - Xanthobacter sp. cyclohexane-1,4-dione + NADH - ? 187921 1.1.1.245 cyclohexane-1,4-diol + NAD+ relative oxidation activity at 36% the rate of cyclohexanol oxidation Pseudomonas sp. cyclohexane-1,4-dione + NADH relative reduction activity at 240% the rate of cyclohexanone reduction r 187921 1.1.1.245 cyclohexane-1,4-diol + NAD+ relative oxidation activity at 91% the rate of cyclohexanol oxidation Nocardia sp. cyclohexane-1,4-dione + NADH - ? 187921 1.1.1.245 cyclohexane-1,4-diol + NAD+ relative oxidation activity at 22% the rate of cyclohexanol oxidation Rhodococcus sp. cyclohexane-1,4-dione + NADH - ? 187921 1.1.1.245 cyclohexanol + NAD+ - Pseudomonas sp. cyclohexanone + NADH - r 186885 1.1.1.245 cyclohexanol + NAD+ - Rhodococcus sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ - Acinetobacter sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ - Nocardia sp. cyclohexanone + NADH reverse reaction at pH 7 ? 186885 1.1.1.245 cyclohexanol + NAD+ preferred substrate Xanthobacter sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ inducible Pseudomonas sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ inducible Acinetobacter sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ metabolism of cyclohexane Pseudomonas sp. cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ metabolism of cyclohexane Xanthobacter sp. cyclohexanone + NADH - r 186885 1.1.1.245 cyclohexanol + NAD+ - Rhodococcus sp. TK6 cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ - Acinetobacter sp. NCIB 9871 cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ inducible Acinetobacter sp. NCIB 9871 cyclohexanone + NADH - ? 186885 1.1.1.245 cyclohexanol + NAD+ - Saccharolobus solfataricus cyclohexanone + NADH + H+ - ? 384491 1.1.1.245 cyclohexanol + NAD+ temperature-induced conformational change is associated with the flexible loops directly involved in the substrate and coenzyme binding Saccharolobus solfataricus cyclohexanone + NADH + H+ - ? 384491 1.1.1.245 cyclooctanol + NAD+ relative activity at 500% the rate of cyclohexanol oxidation Nocardia sp. cyclooctanone + NADH - ? 187929 1.1.1.245 cyclopentanol + NAD+ - Pseudomonas sp. cyclopentanone + NADH relative reduction activity at 4% the rate of cyclohexanone reduction r 187386 1.1.1.245 cyclopentanol + NAD+ relative oxidation activity at 77% the rate of cyclohexanol oxidation Rhodococcus sp. cyclopentanone + NADH - ? 187386 1.1.1.245 cyclopentanol + NAD+ relative oxidation activity at 232% the rate of cyclohexanol oxidation Nocardia sp. cyclopentanone + NADH - ? 187386 1.1.1.245 cyclopentanol + NAD+ relative oxidation activity at 77% the rate of cyclohexanol oxidation Rhodococcus sp. TK6 cyclopentanone + NADH - ? 187386 1.1.1.245 ethane-1,2-diol + NAD+ relative activity at 5% the rate of cyclohexanol oxidation Rhodococcus sp. glyoxal + NADH - ? 187959 1.1.1.245 ethanol + NAD+ relative activity at 20% the rate of cyclohexanol oxidation Rhodococcus sp. acetaldehyde + NADH - ? 186836 1.1.1.245 ethanol + NAD+ relative activity at 20% the rate of cyclohexanol oxidation Rhodococcus sp. TK6 acetaldehyde + NADH - ? 186836 1.1.1.245 hexane-1,2-diol + NAD+ relative activity at 84% the rate of cyclohexanol oxidation Rhodococcus sp. 2-oxohexanal + NADH - ? 187962 1.1.1.245 hexane-1,6-diol + NAD+ relative activity at 21% the rate of cyclohexanol oxidation Rhodococcus sp. hexanedial + NADH - ? 187963 1.1.1.245 methanol + NAD+ relative activity at 2% the rate of cyclohexanol oxidation Rhodococcus sp. formaldehyde + NADH + H+ - ? 186834 1.1.1.245 methanol + NAD+ relative activity at 2% the rate of cyclohexanol oxidation Rhodococcus sp. TK6 formaldehyde + NADH + H+ - ? 186834 1.1.1.245 additional information 2-hydroxycyclohexanone, 1,3,5-trihydroxycyclohexane, menthol, ethanol, 1-propanol, 1-butanol and 1-pentanol are not oxidized with NAD+ Pseudomonas sp. additional information 2-cyclopentenone, 1,3-cyclohexanedione, 1,3-cyclopentanedione and 5-oxocapronate are not reduced with NADH ? 1440 1.1.1.245 additional information cyclohexane-1,2-dione is not oxidized with NAD+ Xanthobacter sp. additional information - ? 1440 1.1.1.245 propane-1,2-diol + NAD+ relative activity at 30% the rate of cyclohexanol oxidation Rhodococcus sp. methylglyoxal + NADH - ? 187960 1.1.1.245 propane-1,3-diol + NAD+ relative activity at 7% the rate of cyclohexanol oxidation Rhodococcus sp. ? + NADH - ? 187961 1.1.1.245 trans-cyclohexane-1,2-diol + NAD+ - Rhodococcus sp. cyclohexane-1,2-dione + NADH + H+ - ? 451018 1.1.1.245 trans-cyclopentane-1,2-diol + NAD+ relative activity at 114% the rate of cyclohexanol oxidation Rhodococcus sp. ? + NADH - ? 187949