1.1.1.215	2,5-diketo-D-gluconate + NADPH	-	5-keto-D-gluconate + NADP+	-	?	187809	
1.1.1.215	2,5-diketo-D-gluconate + NADPH	-	5-keto-D-gluconate + NADP+	-	ir	187809	
1.1.1.215	2-dehydro-D-gluconate + NADPH	-	D-gluconate + NADP+	-	?	187797	
1.1.1.215	2-dehydro-D-gluconate + NADPH	-	D-gluconate + NADP+	-	r	187797	
1.1.1.215	2-keto-L-gluconic acid + NADH + H+	-	L-idonate + NAD+	-	?	440664	
1.1.1.215	2-keto-L-gluconic acid + NADPH + H+	-	L-idonate + NADP+	-	?	440092	
1.1.1.215	2-keto-L-gulonate + NADPH	-	L-idonate + NADP+	-	?	187801	
1.1.1.215	2-keto-L-gulonate + NADPH	-	L-idonate + NADP+	-	r	187801	
1.1.1.215	2-oxo-D-gluconate + NADPH + H+	-	D-gluconate + NADP+	-	?	424494	
1.1.1.215	2-oxo-L-gulonate + NADH + H+	-	L-idonate + NAD+	-	r	438741	
1.1.1.215	2-oxo-L-gulonate + NADPH + H+	-	L-idonate + NADP+	-	?	424495	
1.1.1.215	2-oxo-L-gulonate + NADPH + H+	-	L-idonate + NADP+	-	r	424495	
1.1.1.215	5-keto-D-gluconate + NADPH	-	D-gluconate + NADP+	-	?	187800	
1.1.1.215	D-galactonate + NADP+	-	2-dehydro-D-galactonate + NADPH	-	r	187799	
1.1.1.215	D-gluconate + NADP+	-	2-dehydro-D-gluconate + NADPH	-	?	394817	
1.1.1.215	D-gluconate + NADP+	-	2-dehydro-D-gluconate + NADPH + H+	-	?	404816	
1.1.1.215	D-xylonate + NADPH	-	2-keto-D-xylonate + NADP+	-	?	187802	
1.1.1.215	L-idonate + NAD+	-	2-oxo-L-gulonate + NADH + H+	-	?	439667	
1.1.1.215	L-idonate + NADP+	-	2-keto-L-idonate + NADPH	-	?	187798	
1.1.1.215	L-idonate + NADP+	-	2-oxo-L-gulonate + NADPH + H+	-	r	459773	
1.1.1.215	2-keto-L-gulonate + NADPH	10.8% of activity with 2,5-diketo-D-gluconate	L-idonate + NADP+	-	?	187801	
1.1.1.215	2-dehydro-D-gluconate + NADPH	11.8% of activity with 2,5-diketo-D-gluconate	D-gluconate + NADP+	-	?	187797	
1.1.1.215	2-dehydro-D-gluconate + NADPH	2-keto-D-gluconate, part of non-phosphorylative pathway of carbohydrates predominantly in acetic acid bacteria	D-gluconate + NADP+	-	?	187797	
1.1.1.215	L-idonate + NADP+	best substrate	2-keto-L-idonate + NADPH	-	?	187798	
1.1.1.215	2-keto-L-gulonate + NADPH	betst substrate	L-idonate + NADP+	-	r	187801	
1.1.1.215	additional information	D-xylonate, D-glucose, D-fructose, L-sorbose, 5-keto-D-fructose, D-sorbitol, glycerol	?	-	?	89	
1.1.1.215	2-oxo-D-gluconate + NADH + H+	enzyme shows dual cofactor specificity, being able to use both NADPH and NADH	D-gluconate + NAD+	-	?	425470	
1.1.1.215	2-oxo-D-gluconate + NADPH + H+	enzyme shows dual cofactor specificity, being able to use both NADPH and NADH	D-gluconate + NADP+	-	?	424494	
1.1.1.215	2-dehydro-D-gluconate + NADPH	equal reaction rate of reduction of 2-ketogluconate and oxidation of gluconate with Gluconobacter enzyme	D-gluconate + NADP+	-	r	187797	
1.1.1.215	additional information	for large-scale production of 2-dehydro-D-gluconate, the cells require for formation of 2-dehydro-D-gluconate from D-gluconate oxygen as the final acceptor of electrons formed during the oxidation ofD -gluconate	?	-	?	89	
1.1.1.215	2-dehydro-D-gluconate + NADPH	i.e. 2-keto-D-gluconate, best substrate for Acetobacter ascendens and Gluconobacter	D-gluconate + NADP+	-	r	187797	
1.1.1.215	additional information	no activity on other sugars and sugar acids	?	-	-	89	
1.1.1.215	additional information	no substrates are: 6-phospho-D-gluconate, D-mannonate, D-arabonate	?	-	?	89	
1.1.1.215	5-keto-D-gluconate + NADPH	poor substrate	D-gluconate + NADP+	-	?	187800	
1.1.1.215	acetaldehyde + NADPH + H+	poor substrate	ethanol + NADP+	-	?	139551	
1.1.1.215	L-idonate + NADP+	poor substrate	2-keto-L-idonate + NADPH	-	?	187798	
1.1.1.215	glyoxal + NADPH	reduction at 33% the rate of 2-ketogluconate reduction	?	-	?	187731	
1.1.1.215	glyoxylate + NADPH	reduction at 350% the rate of 2-ketogluconate reduction	glycolate + NADP+	-	?	187805	
1.1.1.215	pyruvate + NADPH + H+	reduction at 7% the rate of 2-ketogluconate reduction	lactate + NADP+	-	?	187803	
1.1.1.215	hydroxypyruvate + NADPH	reduction at 733% the rate of 2-keto-gluconate reduction	2,3-dihydroxypropanoate + NADP+	-	?	187804	
1.1.1.215	2-dehydro-D-gluconate + NADPH	reverse reaction at the same rate by Gluconobacter enzyme	D-gluconate + NADP+	-	r	187797	
1.1.1.215	2-dehydro-D-gluconate + NADPH	strongly preferred reaction of Acetobacter enzyme	D-gluconate + NADP+	-	r	187797	
1.1.1.215	D-gluconate + NADP+	the ability of CHA0 to acidify its environment is largely determined by its ability to produce gluconic acid from glucose	2-dehydro-D-gluconate + NADPH + H+	-	?	404816	
1.1.1.215	D-gluconate + NADP+	the large subunit is the catalytically active enzyme part, high substrate and regiospecificity	2-dehydro-D-gluconate + NADPH	-	?	394817	
1.1.1.215	2-keto-L-gulonate + NADPH	third best substrate	L-idonate + NADP+	-	r	187801	
1.1.1.215	D-galactonate + NADP+	third best substrate	2-dehydro-D-galactonate + NADPH	-	r	187799	
1.1.1.215	D-gluconate + NADP+	wild-type exhibits gluconate-dependent respiration. Genes cj0414 and cj0415, orthologous to GADH, are co-transcribed. Campylobacter jejuni 81–176 does not use gluconate compounds as sole carbon sources. GADH plays a minor role in mouse colonization	2-dehydro-D-gluconate + NADPH + H+	-	?	404816