3.4.22.55 bladder - 664533 3.4.22.55 body wall - 753601 3.4.22.55 bone marrow-derived dendritic cell - 732704 3.4.22.55 bone marrow-derived macrophage - 731559 3.4.22.55 brain embryonic and adult 663875 3.4.22.55 brain embryonic and adult, highest expression in embryonic brain 663875 3.4.22.55 brain fetal 647750 3.4.22.55 BxPC-3 cell PS-341 (bortezomib) induces a dose-dependent apoptosis in association with reactive oxygen species generation and cleavage of caspase-2 to its 33- and 14-kDa fragments. PS-341-induced caspase-2 activation is attenuated by a selective pharmacological inhibitor of cathepsin B (R-3032). Caspase-2 regulates mitochondrial permeability 687504 3.4.22.55 cardiomyocyte - 664548 3.4.22.55 coelomocyte high expression level 753601