4.4.1.15	evolution	the enzyme structurally belongs to the fold type II pyridoxal 5'-phosphate-dependent enzyme family	730698	
4.4.1.15	metabolism	the two cysteine desulfhydrases, L-cysteine desulfhydrase and D-cysteine desulfhydrase, are mainly responsible for the degradation of cysteine in order to generate H2S, they show similar expression patterns in tissues	-, 729125	
4.4.1.15	additional information	active site structure analysis and comparisons, residue Tr287 is important for catalysis, while His80 and Tyr261 may not be directly involved in the degradation of D-Cys, overview	730698	
4.4.1.15	physiological function	D-cysteine desulfhydrase is one of two enzymes mainly responsible for the degradation of cysteine in order to generate H2S, the most important is L-cysteine desulfhydrase, EC 4.4.1.1. Gene expression regulation relationship to drought tolerance in Arabidopsis thaliana, protective effect of H2S against drought, and H2S induces stomatal closure, overview	-, 729125	
4.4.1.15	physiological function	overexpression in Arabidopsis thaliana. Compared with wild-type plants, seed germination, root growth, and stomatal closure of the overexpressing plants are more sensitive to abscisic acid, resulting from upregulation of ABA-responsive genes such as PYR1, ABI1, ABI2, HAB1, HAB2, SnRK2, ABF2, and ABF4. Ooverexpressing plants do not show higher drought resistance than wild-type	748473