3.5.4.33 malfunction disruption of TADA has profound effects on chloroplast translation efficiency, leading to reduced yields of chloroplast-encoded proteins and impaired photosynthetic function 713269 3.5.4.33 malfunction disruption of the wild-type chromosomal copy of tadA results in viable Escherichia coli only when an additional plasmid-borne tadA gene is also present. TadA is essential for viability of eubacterial organisms 719356 3.5.4.33 malfunction suppression of AtTadA gene expression in transgenic Arabidopsis plants by RNAi results in reduced adenosine to inosine editing in the chloroplast tRNA-Arg(ACG) 721023 3.5.4.33 physiological function the wobble inosine tRNA modification is essential for cell cycle progression in the G1/S and G2/M transitions in fission yeast 719843