3.4.22.53	malfunction	calpain 2 depletion impairs mitosis and induces apoptosis, low Capn2 levels induce chromosome alignment defects, the loss of histone H3 threonine 3 phosphorylation at centromeres, and premature sister chromatid separation	708140	
3.4.22.53	malfunction	calpain 2 knockdown in breast cancer cells correlates with reduced in vitro proliferation, migration, and in vivo tumorigenicity as well as reduced Akt activation, increased nuclear FoxO localization, and increased p27Kip1 expression	732050	
3.4.22.53	malfunction	calpain inhibition blocks the increased colonic epithelial cell invasion caused by NM IIA knockdown	707044	
3.4.22.53	malfunction	calpain inhibition favors differentiation of neuronal stem cells. Calpain 2 silencing elicits decreased levels of glial fibrillary acidic protein	732688	
3.4.22.53	malfunction	in vivo knockdown of calpain2 disrupts metastasis among apoptosis-resistant tumors	707980	
3.4.22.53	malfunction	inhibition of calpain activity limits cell migration and in vitro wound healing of IEC-6 cells	717669	
3.4.22.53	malfunction	inhibition of m-calpain induces expression of the adult alpha- and beta-globin genes	709031	
3.4.22.53	malfunction	knockdown of calpain 2 expression or chemical inhibition of calpain activity reduces glioblastoma cell invasion by 90%. Decreased expression of calpain 2 does not influence morphology or migration	718169	
3.4.22.53	malfunction	knockdown of calpain 2 inhibits T cell migration at both the level of single cell tracking and general cell speed	718262	
3.4.22.53	malfunction	knockdown of calpain 2 results in a 2.9fold decrease in the invasion of human glioblastoma cells in zebrafish brain. Calpain 2 knockdown cells demonstrate a 2.3fold lower area of dispersal compared with control cells	732365