3.4.19.1	evolution	acylaminoacyl peptidase is a member of the prolyl oligopeptidase protein family	-, 752387	
3.4.19.1	evolution	enzyme AAP belongs to alpha/beta-hydrolase enzyme superfamily	-, 754201	
3.4.19.1	evolution	the enzyme belongs to a class of serine-type protease belonging to the prolyl oligopeptidase (POP) family. The members of the POP family are involved in numerous metabolic processes	755379	
3.4.19.1	evolution	the enzyme belongs to a serine peptidase family	-, 752584	
3.4.19.1	evolution	the enzyme belongs to the prolyl oligopeptidase family of serine proteases	753902	
3.4.19.1	malfunction	overexpression of AARE/OPH exhibits no apparent effect on the level of oxidized proteins because wild types have inherently high AARE/OPH activity	732661	
3.4.19.1	malfunction	the AtAARE-suppressed plants using RNAi became susceptible to oxidative stress corresponding to enhanced accumulation of oxidized proteins	732661	
3.4.19.1	malfunction	transgenic overexpression of APH results in crystallin cleavage, impaired lens development, and cataract	732175	
3.4.19.1	metabolism	the existence of the acylamino acid-releasing enzyme in archaea suggests that the mechanisms of protein degradation or initiation of protein synthesis or both in archaea may be similar to those in eukaryotes	745261	
3.4.19.1	additional information	enzyme structure modeling and comparison with the enzyme structure from Aeropyrum pernix, overview. Both enzymes share a high structural homology	-, 752694