3.4.16.6	malfunction	absence of Kex1p diminishes HOCl-induced production of reactive oxygen species, apoptosis and protein modification	731598	
3.4.16.6	malfunction	kexA deletion strain shows slightly lower growth speed. Deletion strain exhibits scarcely branched hyphae, whereas an kexA-overexpressing strain exhibits a hyperbranching phenotype	731176	
3.4.16.6	malfunction	LNCap cells treated with CPD siRNA show a decreased NO production and cell viability, but increased apoptosis	732850	
3.4.16.6	malfunction	targeted reduction of CPD in Huh7 cells results in decreased growth and enhanced apoptosis of Huh 7 cells in vitro	731593	
3.4.16.6	physiological function	CpD is the only endogenous carboxypeptidase that cleaves antibody heavy chain C-terminal lysine in CHO cells. Knockdown of CpD by RNAi increases C-terminal lysine levels of antibodies, whereas there is no obvious change in C-terminal lysine levels when carboxypeptidase CpM, CpN, CpB, or CpE is knocked downIn a CpD knockout mutant, C-terminal lysine cleavage is completely abolished	753046	
3.4.16.6	physiological function	CPD-mediated production of nitrix oxide promotes the survival of LNCaP cells	732850	
3.4.16.6	physiological function	protease Kex1p mediates HOCl-induced lethality	731598