2.3.1.190 malfunction acoA, acoB are knocked out individually in Pseudomonas aeruginosa PAO1. The mutants lose the ability to grow in acetoin or 2,3-butanediol -, 756608 2.3.1.190 metabolism the aco operon is essential for utilization of acetoin 757616 2.3.1.190 metabolism the enzyme is involved in 2,3-butanediol catabolism -, 756608 2.3.1.190 metabolism the enzyme is involved in the degradation of the sulfonylurea herbicide nicosulfuron -, 757318 2.3.1.190 additional information disruption of the gene acoA encoding subunit E1alpha results in strains impaired in expression of dephosphate-dependent E1 activity, to remove acetoin from the medium and to grow with acetoin as sole carbon source 704260 2.3.1.190 physiological function the acetoin dehydrogenase enzyme system is responsible for R-acetoin dissimilation. Mutants lose the ability to grow on acetoin as the sole carbon source, and the acetoin accumulated cannot be dissimilated. In the presence of another carbon source, the acetoin accumulated in broth of acetoin dehydrogenase mutants is converted to 2,3-butanediol -, 736592