2.1.1.188 malfunction the inactivation of the enzyme confers telithromycin resistance -, 733110 2.1.1.188 metabolism the enzyme enhances binding of telithromycin to A752 in ribosomes -, 734806 2.1.1.188 physiological function methylation of 23S rRNA nucleotide G748 by RlmAII methyltransferase renders Streptococcus pneumoniae telithromycin susceptible -, 733110