4.4.1.15	evolution	the enzyme structurally belongs to the fold type II pyridoxal 5'-phosphate-dependent enzyme family	
4.4.1.15	metabolism	the two cysteine desulfhydrases, L-cysteine desulfhydrase and D-cysteine desulfhydrase, are mainly responsible for the degradation of cysteine in order to generate H2S, they show similar expression patterns in tissues	
4.4.1.15	additional information	active site structure analysis and comparisons, residue Tr287 is important for catalysis, while His80 and Tyr261 may not be directly involved in the degradation of D-Cys, overview	
4.4.1.15	physiological function	D-cysteine desulfhydrase is one of two enzymes mainly responsible for the degradation of cysteine in order to generate H2S, the most important is L-cysteine desulfhydrase, EC 4.4.1.1. Gene expression regulation relationship to drought tolerance in Arabidopsis thaliana, protective effect of H2S against drought, and H2S induces stomatal closure, overview	
4.4.1.15	physiological function	overexpression in Arabidopsis thaliana. Compared with wild-type plants, seed germination, root growth, and stomatal closure of the overexpressing plants are more sensitive to abscisic acid, resulting from upregulation of ABA-responsive genes such as PYR1, ABI1, ABI2, HAB1, HAB2, SnRK2, ABF2, and ABF4. Ooverexpressing plants do not show higher drought resistance than wild-type