1.1.5.4	drug target	the enzyme is a potential antimalarial drug target	
1.1.5.4	drug target	the enzyme is a potential antimalarial drug target against the apicomplexan parasite Plasmodium falciparum, because the enzyme is absent in humans. Ferulenol inhibits parasite growth and shows strong synergism in combination with atovaquone, an anti-malarial and bc1 complex inhibitor	
1.1.5.4	metabolism	the enzyme is involved in three pathways (mitochondrial electron transport chain, the tricarboxylic acid cycle and the fumarate cycle)	
1.1.5.4	additional information	because of the differences in the redox potentials of NAD+ and quinones, the MQO-catalyzed reaction progresses spontaneously compared to the MDH-catalyzed reaction, EC 1.1.1.37	
1.1.5.4	additional information	oxaloacetate reacts chemically inside the cyanide-insensitive cells to produce a cyanohydrin (2-hydroxynitrile), which is further converted to ammonium. The nitrile is transiently accumulated in cyanide-containing media	
1.1.5.4	physiological function	the enzyme is a component of the electron transfer chain in Pseudomonas pseudoalcaligenes CECT5344 cells, overview	
1.1.5.4	physiological function	the enzyme is involved in cyanide degradation in association with the cyanide-insensitive electron-transfer chain	
1.1.5.4	physiological function	the enzyme is essential for parasite survival, at least, in the intra-erythrocytic asexual stage	
1.1.5.4	physiological function	the enzyme is involved in the pathways of mitochondrial electron transport chain, tricarboxylic acid cycle, and fumarate cycle. The enzyme is essential for the survival of Plasmodium falciparum in asexual stage	
1.1.5.4	physiological function	the enzyme is required for development of experimental cerebral malaria of asexual-blood-stage Plasmodium parasites