3.4.22.43 down there is decreased expression of cathepsin V in lesional atopic dermatitis and psoriasis epidermis at the mRNA level as well as the protein level 3.4.22.43 down siRNA-cathepsin V inhibits the up-regulation of cathepsin V-induced by L-homocysteine 3.4.22.43 up CTSL2 transcript levels are strongly elevated in endometrial cancer, particularly in G3 tumors 3.4.22.43 up E2F1 activates cathepsin like 2 gene promoter activity 3.4.22.43 up tissue necrosis factor alpha increases cathepsin V expression and activity by 2fold. Tissue necrosis factor alpha and co-culturing with THP-1 monocytes stimulates a 460% increase in cathepsin V active enzyme 3.4.22.43 up L-homocysteine induces cathepsin V expression, L-homocysteine promoted cathepsin V expression in HUVECs. Methylation of the promoter region of cathepsin V is decreased following L-Hcy stimulation