2.7.1.199 down enzyme expression is repressed by the DeoR-type regulator SugR, RamB, and GlxR -, 736622 2.7.1.199 down expression of the major ptsG transcript is induced by repressed by the Mlc protein 736823 2.7.1.199 down in the absence of glucose, ptsG expression is repressed by the repressor Mlc, while in the presence of glucose Mlc is inactivated by binding to the dephosphorylated EIIBGlc domain of the EIICBGlc during glucose transport 736356 2.7.1.199 down phospho-ArcA represses ptsG P1 transcription by decreasing the cAMP receptor protein binding 736401 2.7.1.199 down transcription of ptsG is regulated by the repressor Mlc -, 736758 2.7.1.199 up protein YeeI is involved in the regulation of gene expression by inactivating repressor Ml. The enzyme synthesis is increased 6.2fold after addition of 0.2% (w/v) D-glucose 736353 2.7.1.199 up the enzyme expression is higher in D-glucose media than in glycerol. A mutation in the mlc gene greatly enhances enzyme expression in a glycerol-grown culture but has no effect on enzyme expression during growth on D-glucose 736823 2.7.1.199 up the presence of GlcT protein enables constitutive expression of the glcA gene 736757 2.7.1.199 up the transcriptional regulators GntR1 and GntR2 activate the enzyme expression -, 736622 2.7.1.199 up the umgC mutation (which allows a strain mutated in the mannose phosphotransferase system to grow on glucosamine) enhances enzyme mRNA levels -, 736758