1.14.13.148	additional information	no changes in relative FMO3 mRNA levels are observed with 50 nM trichostatin A	
1.14.13.148	additional information	the enzyme is absent during growth on methanol	
1.14.13.148	up	5-aza-2'-deoxycytidine at 0.001 mM and 0.0025 mM results in 6.6fold and 9.2fold increases in FMO3 mRNA levels, respectively. HNF4alpha transient expression results in a 3.1fold increase in FMO3 mRNA levels. Co-transfection of HepG2 cells with the CCAAT/enhancer-binding protein beta expression vector and the pRNH694 reporter construct results in a dose-dependent increase in FMO3 promoter activity with a maximal 2fold increase using 0.001 mg of expression	
1.14.13.148	up	the enzyme is highly expressed in N,N,N-trimethylamine-grown Methylocella silvestris