2.3.1.191 757609 Effects of lipid A acyltransferases on the pathogenesis of F. novicida Microb. Pathog. 109 313-318 2017 Francisella tularensis subsp. novicida http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28478203&form=6&db=m 2.3.1.191 755699 Structural and biological basis of small molecule inhibition of Escherichia coli LpxD acyltransferase essential for lipopolysaccharide biosynthesis ACS Infect. Dis. 6 1480-1489 2019 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31402665&form=6&db=m 2.3.1.191 737072 A complete pathway model for lipid A biosynthesis in Escherichia coli PLoS ONE 10 e0121216 2014 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25919634&form=6&db=m 2.3.1.191 718571 A continuous fluorescent enzyme assay for early steps of lipid A biosynthesis Anal. Biochem. 425 21-27 2012 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22381368&form=6&db=m 2.3.1.191 698587 Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis J. Bacteriol. 190 4549-4558 2008 Porphyromonas gingivalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18456814&form=6&db=m 2.3.1.191 698587 Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis J. Bacteriol. 190 4549-4558 2008 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18456814&form=6&db=m 2.3.1.191 736880 Chasing acyl carrier protein through a catalytic cycle of lipid A production Nature 505 422-426 2014 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24196711&form=6&db=m 2.3.1.191 696356 Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis Biochemistry 48 8672-8683 2009 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19655786&form=6&db=m 2.3.1.191 694027 Expression of Legionella pneumophila paralogous lipid A biosynthesis genes under different growth conditions Microbiology 153 3817-3829 2007 Legionella pneumophila http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17975091&form=6&db=m 2.3.1.191 735568 Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa Arch. Microbiol. 197 135-145 2015 Pseudomonas aeruginosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25173672&form=6&db=m 2.3.1.191 735568 Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa Arch. Microbiol. 197 135-145 2015 Pseudomonas aeruginosa UCBPP-PA14 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25173672&form=6&db=m 2.3.1.191 698088 Isolation and characterization of the Neisseria meningitidis lpxD-fabZ-lpxA gene cluster involved in lipid A biosynthesis Gene 190 263-270 1997 Neisseria meningitidis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9197543&form=6&db=m 2.3.1.191 736235 Leptospira interrogans lpxD homologue is required for thermal acclimatization and virulence Infect. Immun. 83 4314-4321 2015 Leptospira interrogans http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26283339&form=6&db=m 2.3.1.191 736235 Leptospira interrogans lpxD homologue is required for thermal acclimatization and virulence Infect. Immun. 83 4314-4321 2015 Leptospira interrogans L495 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26283339&form=6&db=m 2.3.1.191 720944 LPS remodeling is an evolved survival strategy for bacteria Proc. Natl. Acad. Sci. USA 109 8716-8721 2012 Francisella tularensis subsp. novicida http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22586119&form=6&db=m 2.3.1.191 720944 LPS remodeling is an evolved survival strategy for bacteria Proc. Natl. Acad. Sci. USA 109 8716-8721 2012 Francisella tularensis subsp. novicida U112 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22586119&form=6&db=m 2.3.1.191 695627 Outer membrane permeability barrier in Escherichia coli mutants that are defective in the late acyltransferases of lipid A biosynthesis Antimicrob. Agents Chemother. 43 1459-1462 1999 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10348770&form=6&db=m 2.3.1.191 720913 Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli Proc. Natl. Acad. Sci. USA 108 11387-11392 2011 Arabidopsis thaliana http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21709257&form=6&db=m 2.3.1.191 720913 Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli Proc. Natl. Acad. Sci. USA 108 11387-11392 2011 Arabidopsis thaliana Col-0 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21709257&form=6&db=m 2.3.1.191 736185 Pleiotropic effects of acyltransferases on various virulence-related phenotypes of Pseudomonas aeruginosa Genes Cells 18 682-693 2013 Pseudomonas aeruginosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23848169&form=6&db=m 2.3.1.191 698693 Raetz, C.R.; Anderson, M.S.: The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis J. Biol. Chem. 268 19866-19874 1993 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8366125&form=6&db=m 2.3.1.191 696264 Steady-state kinetics and mechanism of LpxD, the N-acyltransferase of lipid A biosynthesis Biochemistry 47 5290-5302 2008 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18422345&form=6&db=m 2.3.1.191 736449 Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis J. Biol. Chem. 289 15527-15535 2014 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24742680&form=6&db=m 2.3.1.191 700935 Structure and reactivity of LpxD, the N-acyltransferase of lipid A biosynthesis Proc. Natl. Acad. Sci. USA 104 4321-4326 2007 Chlamydia trachomatis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17360522&form=6&db=m 2.3.1.191 735384 Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii Acta Crystallogr. Sect. F 69 6-9 2013 Acinetobacter baumannii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23295477&form=6&db=m 2.3.1.191 735384 Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii Acta Crystallogr. Sect. F 69 6-9 2013 Acinetobacter baumannii SDF http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23295477&form=6&db=m 2.3.1.191 697921 The novel hexapeptide motif found in the acyltransferases LpxA and LpxD of lipid A biosynthesis is conserved in various bacteria FEBS Lett. 337 289-292 1994 Yersinia enterocolitica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8293817&form=6&db=m 2.3.1.191 718513 The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution Acta Crystallogr. Sect. F 67 749-752 2011 Pseudomonas aeruginosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21795786&form=6&db=m