6.2.1.45	A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes	Arabidopsis thaliana	
6.2.1.45	A viable ubiquitin-activating enzyme mutant for evaluating ubiquitin system function in Saccharomyces cerevisiae	Saccharomyces cerevisiae	
6.2.1.45	Changes in expression of interferon-stimulated genes and ubiquitin activating enzyme E1-like in ovine thymus during early pregnancy	Ovis aries	
6.2.1.45	Comparative proteomic analysis of wild-type and SAP domain-mutant Foot-and-mouth disease virus (FMDV)-infected porcine cells identifies the ubiquitin-activating enzyme UBE1 required for virus replication	Sus scrofa	
6.2.1.45	Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation	Homo sapiens	
6.2.1.45	Construction of a mouse Aos1-Uba2 chimeric SUMO-E1 enzyme, mAU, and its expression in baculovirus-insect cells	Mus musculus	
6.2.1.45	Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme	Homo sapiens	
6.2.1.45	Crystal structure of UBA2ufd-Ubc9: Insights into E1-E2 interactions in Sumo pathways	Saccharomyces cerevisiae	
6.2.1.45	Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6	Homo sapiens	
6.2.1.45	Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes	Schizosaccharomyces pombe	
6.2.1.45	Direct catalysis of lysine 48-linked polyubiquitin chains by the ubiquitin-activating enzyme	Escherichia coli	
6.2.1.45	Expression, purification and characterization of human ubiquitin-activating enzyme, UBE1	Homo sapiens	
6.2.1.45	Expression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)	Homo sapiens	
6.2.1.45	High-yield expression in Escherichia coli and purification ofmouse ubiquitin-activating enzyme E1	Mus musculus	
6.2.1.45	Homology modelling of human E1 ubiquitin activating enzyme	Homo sapiens	
6.2.1.45	Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme	Homo sapiens	
6.2.1.45	Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics	Mus musculus	
6.2.1.45	Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics	Homo sapiens	
6.2.1.45	Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (E1)	Homo sapiens	
6.2.1.45	Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (E1)	Schizosaccharomyces pombe	
6.2.1.45	LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6	Homo sapiens	
6.2.1.45	Molecular characterization and expression analysis of ubiquitin-activating enzyme E1 gene in Citrus reticulata	Citrus reticulata	
6.2.1.45	Molecular characterization of the thermosensitive E1 ubiquitin-activating enzyme cell mutant A31N-ts20. Requirements upon different levels of E1 for the ubiquitination/degradation of the various protein substrates in vivo	Mus musculus	
6.2.1.45	Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1	Homo sapiens	
6.2.1.45	Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment	Drosophila melanogaster	
6.2.1.45	Mutation of the gene encoding the ubiquitin activating enzyme Uba1 causes tissue overgrowth in Drosophila	Drosophila melanogaster	
6.2.1.45	NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme	Mus musculus	
6.2.1.45	Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes	Homo sapiens	
6.2.1.45	Pleiotropic effects of ATP*Mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme	Homo sapiens	
6.2.1.45	Steady-state kinetic analysis of human ubiquitin-activating enzyme (E1) using a fluorescently labeled ubiquitin substrate	Homo sapiens	
6.2.1.45	Structural and functional characterisation of the domains of ubiquitin-activating enzyme (E1) of Saccharomyces cerevisiae	Saccharomyces cerevisiae	
6.2.1.45	Structural and functional characterisation of the domains of ubiquitin-activating enzyme (E1) of Saccharomyces cerevisiae	Saccharomyces cerevisiae ATCC 204508	
6.2.1.45	Substrate properties of site-specific mutant ubiquitin protein (G76A) reveal unexpected mechanistic features of ubiquitin-activating enzyme (E1)	Bos taurus	
6.2.1.45	Targeting the E1 ubiquitin-activating enzyme (UBA1) improves elexacaftor/tezacaftor/ivacaftor efficacy towards F508del and rare misfolded CFTR mutants	Homo sapiens	
6.2.1.45	The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells	Homo sapiens	
6.2.1.45	The pivotal role of ubiquitin-activating enzyme E1 (UBA1) in neuronal health and neurodegeneration	Homo sapiens	
6.2.1.45	The role of ginsenosides in inhibiting ubiquitin activating enzyme (E1) activity	Homo sapiens	
6.2.1.45	The ubiquitin-activating enzyme (E1) gene family in Arabidopsis thaliana	Arabidopsis thaliana	
6.2.1.45	The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation	Giardia duodenalis	
6.2.1.45	The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation	Giardia duodenalis ATCC 50803	
6.2.1.45	The ubiquitin-activating enzyme E1 as a novel therapeutic target for the treatment of restenosis	Homo sapiens	
6.2.1.45	The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma	Homo sapiens	
6.2.1.45	The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma	Mus musculus	
6.2.1.45	Trans-binding mechanism of ubiquitin-like protein activation revealed by a UBA5-UFM1 complex	Homo sapiens	
6.2.1.45	Two mutations impair the stability and function of ubiquitin-activating enzyme (E1)	Mus musculus	
6.2.1.45	UBE1DC1, an ubiquitin-activating enzyme, activates two different ubiquitin-like proteins	Homo sapiens	
6.2.1.45	UBE1L2, a novel E1 enzyme specific for ubiquitin	Homo sapiens	
6.2.1.45	UBE1L2, a novel E1 enzyme specific for ubiquitin	Mus musculus