4.2.1.22 L-serine + L-homocysteine = L-cystathionine + H2O carbanion and aminacrylate intermediates in the CBS-catalyzed reaction, arrangement of the protein residues and pyridoxal 5'-phosphate cofactor in the active site pocket, and reaction mechanism, overview 716763 4.2.1.22 L-serine + L-homocysteine = L-cystathionine + H2O mechanism 650019, 650128, 650408, 652127, 652270 4.2.1.22 L-serine + L-homocysteine = L-cystathionine + H2O ping-pong mechanism 650238, 652551 4.2.1.22 L-serine + L-homocysteine = L-cystathionine + H2O sequential bisubstrate mechanism in which no product release occurs until both substrates are bound to the enzyme to form a ternary complex 5597