3.7.1.3	L-kynurenine + H2O = anthranilate + L-alanine	A pyridoxal-phosphate protein.	-	
3.7.1.3	L-kynurenine + H2O = anthranilate + L-alanine	a pyridoxal-phosphate protein. Also acts on 3'-hydroxykynurenine and some other (3-acrylcarbonyl)-alanines, hydrolytic beta,gamma-cleavage of aryl-substituted gamma-keto-alpha-amino acids	-	
3.7.1.3	L-kynurenine + H2O = anthranilate + L-alanine	aldol and retro-aldol reactions	-	
3.7.1.3	L-kynurenine + H2O = anthranilate + L-alanine	catalytic reaction mechanism via several intermediates, e.g. external aldimine, quinonoid, ketimine, Gem-diolate, and enamine	733495	
3.7.1.3	L-kynurenine + H2O = anthranilate + L-alanine	the proposed mechanism of the retro-Claisen reaction requires extensive acid/base catalysis, the phosphate of pyridoxal 5'-phosphate is an acid/base catalyst in the mechanism of Pseudomonas fluorescens kynureninase, Tyr226 hydrogen bonds to the phosphate of the pyridoxal 5'-phosphate cofactor. Tyr226 mediates proton transfer between the substrate and the phosphate, which accelerates formation of external aldimine and gem-diol intermediates, catalytic reaction mechanism via several intermediates, e.g. external aldimine, quinonoid, ketimine, Gem-diolate, and enamine, overview	733832