3.4.22.43 glycoprotein - 717159 3.4.22.43 glycoprotein N-glycosylation of extracellular proenzyme and mature enzyme 668763 3.4.22.43 glycoprotein recombinant enzyme is partially and heterogenously glycosylated 137269 3.4.22.43 glycoprotein three potential N-lycosylation sites 137271 3.4.22.43 proteolytic modification autoactivation of the inactive extracellular zymogen at pH 4.0 and 37°C to the active mature protein 668763 3.4.22.43 proteolytic modification the recombinant enzyme is activated by pepsin treatment and further purified by gel filtration 669257