2.7.1.151 additional information the enzyme can be phosphorylated by protein kinase C in vitro 2.7.1.151 phosphoprotein - 2.7.1.151 phosphoprotein glucose activates phosphorylation of IPMK at residue Tyr174 enabling the enzyme to bind to AMP-activated kinase and regulate its activation 2.7.1.151 phosphoprotein inhibition of p110 phosphatidylinositol 3-kinases by wortmannin prevents IPMK phosphorylation and activation